Search Results (1,211)

Increasing environmental and economic pressures have led to numerous innovations in the logistics sector, including integrated people and freight transport (IPFT). Despite growing attention from practitioners and researchers, IPFT lacks extensive research coverage. This study aims to bridge this gap by presenting a general framework and making several key contributions. It identifies, researches, and explains relevant terminologies, such as cargo hitching, freight on transit (FoT), urban co-modality, crowd-shipping (CS), occasional drivers (OD), crowdsourced delivery among friends, and share-a-ride, illustrating the interaction of IPFT with different systems like the sharing economy and co-modality. Furthermore, it classifies IPFT-related studies at strategic, tactical, and operational decision levels, detailing those that address uncertainty. The study also analyzes the opportunities and challenges associated with IPFT, highlighting social, economic, and environmental benefits and examining challenges from a PESTEL (political, economic, social, technological, environmental, and legal) perspective. Additionally, it discusses practical applications of IPFT and offers recommendations for future research and development, aiming to guide practitioners and researchers in addressing existing challenges and leveraging opportunities. This comprehensive framework aims to significantly advance the understanding and implementation of IPFT in the logistics sector. Full article

The worldwide launch of neoliberalism ushered everyone into an atomized society. Neoliberalism transforms Homo sapiens into Homo economicus, a narcissistic self-entrepreneur that positions their body as a factory, skills as resources, and earnings as products while relying less on others. Such atomization of individuals undermines the community. Following the Cartesian moment, enlightenment, and postmodernism’s later wave, the world is disenchanted, deprived of unity in the form of community fragmentation. Foucault offered a Greco–Roman philosophical remedy for contemporary society, focusing on the formulation of ‘Spiritual-Corporality’ through the practice of care of the self. Foucault believed the one who takes good care of himself is often self-assured of his ability, expectations, and missions in relationships with others, he does not resort to tyranny in those relationships, giving him an ethical advantage in caring for his family and fellow citizens. If everyone strives to take care of themselves, the city-state will prosper. However, Foucault relied on Stoic philosophy over other ancient schools and failed to provide concrete practices on how to bind ourselves with others through care of the self. In partial agreement with Foucault, the present study chooses Hadot’s spiritual exercise as a more accurate terminology to justify Greco–Roman philosophies’ affordance to contemporary social unification. After reviewing the philosophies of Aristotle, the Stoics, and Epicurus, the present study selected the spiritual exercises of ‘hitting the mean as deliberation’, ‘reframing of self’, and ‘thinking outside the box’ as suitable practices for community flourishing. Full article

The Yogalehrbuch is said to have been established in Central Asia and to have a similar terminology to the Sarvāstivāda. However, the exact background of the relation is yet unknown. This paper discusses two points. First, I examine the structure of ānāpānasmṛti and how the meditative images relate to the descriptions of Abhidharmic texts. The results show that the Yogalehrbuch adopts the steps of the Sarvāstivāda but does not reflect a highly systematized doctrine. The second is a comparison of its unique meditative images (oil, abhiṣeka, the Buddhas of the past, and Maitreya) with two meditation manuals, the Secret Essentials and the Methods of Curing, and two early esoteric sūtras. The results show that the abhiṣeka in the Yogalehrbuch is close to the two meditation manuals, while it represents more the life of Śākyamuni, which is also found in esoteric Buddhism, rather than the healing of illness. However, the Methods of Curing refers to a dhāraṇī similar to those found in two esoteric sūtras. The two sūtras use abhiṣeka as the name of dhāraṇīs, not as meditative images. From the above, it is hypothesized that the Yogalehrbuch was established within a background in which elements of early esoteric Buddhism could be found but had not yet seen the development of dhāraṇīs. Full article

Background: Stereotactic body radiotherapy (SBRT) is an evolving treatment for the local management of pancreatic cancer (PC). The main purpose of this study is to report our initial experience in terms of local control (LC) and toxicity for PC patients treated with SBRT. Methods: We conducted a retrospective review of patients treated with SBRT using abdominal compression (AC) or an end-expiratory breath-holding (EEBH) technique. The median prescribed dose was 35 Gy, delivered in five fractions. Toxicities were recorded using Common Terminology Criteria for Adverse Events (CTCAE) v5.0, and survival was estimated using the Kaplan–Meier method. Results: From 2017 to 2023, 17 PC patients were offered SBRT. Their median age was 69 years. The median follow-up from the date of diagnosis was 22.37 months. The overall survival (OS) was 94% at 1 year and 60.9% at 2 years. The progression-free survival (PFS) was 63.1% at 6 months and 56.1% at 9 months. The median OS was 26.3 months, and the median PFS was 20.6 months. The 6-month and 1-year LC rates were 71% and 50.8%, respectively. Conclusion: We are successful in implementing the SBRT program at our centre. SBRT appears to be a promising treatment option for achieving LC with limited acute toxicities. Full article

This microreview, conducted by interdisciplinary teams, examines complex heritage material systems, such as medieval colors and modern and contemporary artworks. Our multi-analytical approach, a significant aspect of our research, is a means to this end. The conservation of works of art is our shared goal, as it ensures their accessibility and the transfer of cultural heritage to future generations. We seek to interpret the damage, usefulness, and innovation of the experimental design in this context. As Jan Wouters rightly points out, “The terminology used nowadays to describe the potential damage to objects caused by analysis should be refined beyond the destructiveness/non-invasiveness polarization. A terminology should include at least degree level intervention (low, medium, high), usefulness, and innovation”. Complementing micro- or sub-micro-sampling with the appropriate analytical methods is crucial, as exemplified in medieval, modern, and contemporary collections studies. Finally, a novel perspective for exploring the information contained in the multiscale heterogeneity of organic historical materials is envisaged, and it includes UV/Visible photoluminescence spectral imaging using a low-intensity ultraviolet synchrotron beam. Full article

From the late 17th to the early 18th century, Europe witnessed various intellectual debates, and it undeniably received help from places outside Europe such as China. When Chinese history, culture and thought, especially the Confucian classics translated into Latin, were introduced to Europe, they provided resources for comparison and reference for Europe’s ideological crisis. Confucius ou la Science des Princes, the Confucian classic translated by François Bernier, is a typical example. From the perspective of the cross-cultural history of ideas, after carefully analyzing the terminology used in Bernier’s translation and his understanding of Confucius’s thought, this paper will show that Bernier accepted, through the Jesuit translation, the non-religious dimension of politics and ethics in Confucianism, but unlike the Jesuits, he did not see Confucianism as needing Christianity; on the contrary, he believed that politics and ethics could be based on a purely secular philosophy. Based on his secular understanding of Confucius’s thought, Bernier reconstructed Confucius’s texts as a manual to teach European princes, regarding the prince’s virtue, reason and benevolence as the foundation of a country’s good government. Full article

Probiotics are thought to be effective in the treatment of radiation-induced enteropathy (RIE). However, little is known regarding their efficacy in preventing RIE. In this prospective, randomized, double-blinded, placebo-controlled, single-center study, the incidence of grade 2 acute RIE was compared and the safety of probiotics was evaluated. Patients receiving pelvic radiotherapy for a minimum of 40 Gy at the pelvic level were randomized into two groups: (i) a probiotic group receiving Bacillus licheniformis from two weeks before radiotherapy until the end and (ii) a control group receiving a placebo with the same schedule. The toxicities of 234 patients were graded according to the Common Terminology Criteria for Adverse Events v5.0. Grade 1 RIE was observed in 65 (56%) of the probiotics group compared with 75 (64%) of the placebo group. Grade 2 RIE occurred in 30 patients (26%) in the probiotics group compared with 26 (22%) in the placebo group, indicating that probiotics failed in their preventive role compared with placebo (p = 0.493). Medication adherence rates were good, and no difference was observed between the two arms. These findings suggest that B. licheniformis does not significantly prevent RIE. Full article

The objective was to review the existing literature reporting on spontaneous abortion (SA) and intrauterine fetal demise (IUFD) associated with cytomegalovirus (CMV) infection. A review using standardized terminology such as ‘intrauterine fetal death’, ‘congenital cytomegalovirus’ and ‘CMV’ was performed using PubMed and Embase (Medline) using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. Twenty-one studies met inclusion criteria. CMV was identified as a potential or likely factor in a median of 7.1% of SA or IUFD in study cohorts. Of the studies, 11 used fetal remains, 18 used placenta, 6 used serum, and 1 used post-mortem dried blood spot as specimens for testing for CMV. Features commonly observed were fetal thrombotic vasculopathy, hydrops fetalis and chronic villitis. CMV is frequently noted in studies evaluating viral etiologies of SA or IUFD. Large population-based studies are needed to estimate the incidence of CMV-associated SA or IUFD. CMV and congenital CMV should be included on the differential diagnosis in all cases of SA or IUFD of unknown etiology. Full article

Stress resistance is highly associated with longer and healthier lifespans in various model organisms, including nematodes, fruit flies, and mice. However, we lack a complete understanding of stress resistance in humans; therefore, we investigated how stress resistance and longevity are interlinked in humans. Using more than 180 databases, we identified 541 human genes associated with stress resistance. The curated gene set is highly enriched with genes involved in the cellular response to stress. The Reactome analysis identified 398 biological pathways, narrowed down to 172 pathways using a medium threshold (p-value < 1 × 10⁻⁴). We further summarized these pathways into 14 pathway categories, e.g., cellular response to stimuli/stress, DNA repair, gene expression, and immune system. There were overlapping categories between stress resistance and longevity, including gene expression, signal transduction, immune system, and cellular responses to stimuli/stress. The categories include the PIP3-AKT-FOXO and mTOR pathways, known to specify lifespans in the model systems. They also include the accelerated aging syndrome genes (WRN and HGPS/LMNA), while the genes were also involved in non-overlapped categories. Notably, nuclear pore proteins are enriched among the stress-resistance pathways and overlap with diverse metabolic pathways. This study fills the knowledge gap in humans, suggesting that stress resistance is closely linked to longevity pathways but not entirely identical. While most longevity categories intersect with stress-resistance categories, some do not, particularly those related to cell proliferation and beta-cell development. We also note inconsistencies in pathway terminologies with aging hallmarks reported previously, and propose them to be more unified and integral. Full article

Clinicians have a sincere desire to ensure that the decision-making processes of seriously ill patients are well informed throughout illness trajectories. A quagmire of variable terminology (e.g., advance care planning, serious illness conversations, goals-of-care discussions, etc.), however, currently predominates the field of serious illness communication. This creates uncertainty among clinicians as to the overall purpose, tasks, and specific outcomes of conversations that address serious illness. The Preparing or Deciding model is a unifying framework that provides conceptual clarity by helping clinicians understand their role in leading these important conversations. The Preparing or Deciding model simply posits that conversations with seriously ill patients are about either preparing or deciding. It considers these tasks to be mutually exclusive, which can help bypass many of the barriers to having these conversations. The Preparing or Deciding model compliments all existing resources and frameworks and is applicable to all healthcare practitioners in every care setting. To help move forward serious illness communication education and research, as well as process improvement efforts more effectively, here, we describe the Preparing or Deciding model. Full article

This article offers a fresh exegesis of Heidegger’s philosophy of art, focusing on his conceptualization of artwork as the reproduction of the thing’s general essence. Grounding the analysis in Heidegger’s revisit of Kant’s Transcendental Aesthetic, this study explores Heidegger’s interpretation of a thing as a “composed homogeneity” that reveals inherent determinations of temporality and spatiality in the self-presence of beings as a phenomenon grasped within finite human cognition. This is inextricably linked to the ecstatic temporality of Dasein, elucidating a cyclical human–thing dynamic integral to Heidegger’s ontology. Going deeper, I draw parallels between Kant’s “supersensible” realm and Heidegger’s “earth”, revealing a teleological (ethical) design manifested in art that captures the dual essence of Nature—using Kantian terminology, its purposiveness and contrapurposiveness—intersecting with Heidegger’s notion of the counter-essence of ἀλήθεια in relation to freedom. Finally, I show how the manifold aesthetic metamorphoses of this existential scheme within the existentiell ordinariness through nonradiant φαίνεσθαι, such as equipmentality, emerge as the everyday incarnation of this design. Full article

Explainable artificial intelligence (XAI) is crucial for enhancing transparency and trust in machine learning models, especially for tabular data used in finance, healthcare, and marketing. This paper surveys XAI techniques for tabular data, building on] previous work done, specifically a survey of explainable artificial intelligence for tabular data, and analyzes recent advancements. It categorizes and describes XAI methods relevant to tabular data, identifies domain-specific challenges and gaps, and examines potential applications and trends. Future research directions emphasize clarifying terminology, ensuring data security, creating user-centered explanations, improving interaction, developing robust evaluation metrics, and advancing adversarial example analysis. This contribution aims to bolster effective, trustworthy, and transparent decision making in the field of XAI. Full article

Innovative initiatives emerge in line with the recommendations of the United Nations Convention on the Rights of Persons with Disabilities. They are often place-based, context-dependent, and are not easily adapted for use in other contexts. It raises the question of their transferability. This concept has been studied in the field of public health. To explore the conditions surrounding the transfer of disability interventions, this study aims to determine the advances related to the transferability of complex interventions in public health. A review was conducted. Data were analyzed according to the concepts and terms used to describe the terminology related to transferability and the processes used to manage, assess, and report transferability. Fourteen papers fulfilled the inclusion criteria. The analysis shows that different terms and concepts are used. Numerous tools or frameworks have been developed to structure the identification of transferability factors or adaptations and usually require the involvement of stakeholders. Considering context is central. Finally, we identified a lack of reporting. This review provides a structured and operational framework for various concepts, including transferability as a form of knowledge generation, and implementation/adaptation as proactive actions. It emphasizes that a holistic approach to assessing transferability involves shifting the focus from transferability factors to understanding mechanisms of change and their interactions with the context. The review highlights the pivotal role of stakeholders in generating knowledge, capturing diverse contexts, and prioritizing information. Ultimately, this work will serve as a valuable foundation for guiding methodological developments on transferability in the field of disability. Full article

The electroencephalogram (EEG) is a cornerstone tool for the diagnosis, management, and prognosis of selected patient populations. EEGs offer significant advantages such as high temporal resolution, real-time cortical function assessment, and bedside usability. The quantitative EEG (qEEG) added the possibility of long recordings being processed in a compressive manner, making EEG revision more efficient for experienced users, and more friendly for new ones. Recent advancements in commercially available software, such as Persyst, have significantly expanded and facilitated the use of qEEGs, marking the beginning of a new era in its application. As a result, there has been a notable increase in the practical, real-world utilization of qEEGs in recent years. This paper aims to provide an overview of the current applications of qEEGs in daily neurological emergencies and ICU practice, and some elementary principles of qEEGs using Persyst software in clinical settings. This article illustrates basic qEEG patterns encountered in critical care and adopts the new terminology proposed for spectrogram reporting. Full article

Several terminologies exist for a vestigial muscle connecting the clavicle to the cervical vertebrae; however, “levator claviculae muscle” and “cleidocervical muscle” are commonly found in the contemporary literature. The term “levator claviculae” does not determine the location of the superior insertion point, but rather describes a single function of the muscle. However, similar to the sternocleidomastoid muscle, the bilateral presence of this muscle could result not only in increased strength for elevating the clavicle, but also in enhanced neck flexion and greater neck stability. To provide anatomical precision, the muscle could be more accurately termed the cleidocervical muscle. This literature review was performed using “PubMed” as the search engine. Mesh terms such as levator AND claviculae, cleidocervicalis, cleidocervical, cleidoatlanticus, and cleidotrachelian were used. Our proposal for a precise methodology in addressing the terminology would be as follows: [Position 1: cleidocervical muscle] [Position 2: vertebra levels]. In this opinion paper, we advocate for the anatomical community to discontinue the use of the term “levator claviculae” and instead adopt the more appropriate “cleidocervical muscle” in academic discourse. Full article