Search Results (60)

Prescribed burning is a cost-effective method for reducing hazardous fuels in pine- and oak-dominated forests, but smoke emissions contribute to atmospheric pollutant loads, and the potential exists for exceeding federal air quality standards designed to protect human health. Fire behavior during prescribed burns influences above-canopy sensible heat flux and turbulent kinetic energy (TKE) in buoyant plumes, affecting the lofting and dispersion of smoke. A more comprehensive understanding of how enhanced energy fluxes and turbulence are related during the passage of flame fronts could improve efforts to mitigate the impacts of smoke emissions. Pre- and post-fire fuel loading measurements taken during 48 operational prescribed burns were used to estimate the combustion completeness factors (CC) and emissions of fine particulates (PM_2.5), carbon dioxide (CO₂), and carbon monoxide (CO) in pine- and oak-dominated stands in the Pinelands National Reserve of southern New Jersey. During 11 of the prescribed burns, sensible heat flux and turbulence statistics were measured by tower networks above the forest canopy. Fire behavior when fire fronts passed the towers ranged from low-intensity backing fires to high-intensity head fires with some crown torching. Consumption of forest-floor and understory vegetation was a near-linear function of pre-burn loading, and combustion of fine litter on the forest floor was the predominant source of emissions, even during head fires with some crowning activity. Tower measurements indicated that above-canopy sensible heat flux and TKE calculated at 1 min intervals during the passage of fire fronts were strongly influenced by fire behavior. Low-intensity backing fires, regardless of forest type, had weaker enhancement of above-canopy air temperature, vertical and horizontal wind velocities, sensible heat fluxes, and TKE compared to higher-intensity head and flanking fires. Sensible heat flux and TKE in buoyant plumes were unrelated during low-intensity burns but more tightly coupled during higher-intensity burns. The weak coupling during low-intensity backing fires resulted in reduced rates of smoke transport and dispersion, and likely in more prolonged periods of elevated surface concentrations. This research facilitates more accurate estimates of PM_2.5, CO, and CO₂ emissions from prescribed burns in the Pinelands, and it provides a better understanding of the relationships among fire behavior, sensible heat fluxes and turbulence, and smoke dispersion in pine- and oak-dominated forests. Full article

The research and development of a new disc filter is a key link in intelligent irrigation systems, the core of efficient and water-saving irrigation development, and also an important joint effort to ensure a clean water source in micro-irrigation systems. In this paper, the independent research and development of the fractal flow passage disc filter was taken as the research object, and the disc filter numerical simulation cell (FLUENT) and artificial intelligence technology (Back Propagation Neural Network) were combined to optimize the filter flow channel parameters, including the tilt angle, the length and height of the bottom of the internal section triangle, the taper, the position and number of buffer slots, etc. A new type of disc filter with lower head loss, larger flow capacity, higher filtration efficiency, and longer running time is proposed. It has certain reference value and promotion significance for the future development and design of high-performance disc filters and their wide use. Full article

Chronic back pain in adults is often a cause of absenteeism from work, limitations in social interactions, and difficulties in performing daily activities. This study aimed to check whether the functioning of everyday activities in elderly patients after neurosurgery improved over time compared to their condition before the procedure and whether there is a connection between fitness, self-esteem, and pain intensity. This was a cross-sectional study carried out using an anonymous survey. This study included patients over 60 years of age from the neurosurgical ward. The following scales were used to assess cognitive functioning, depression, functional status: basic and instrumental activities of daily living (IADL), back pain disability (QBPDS), pain intensity, and self-esteem. The level of independence in terms of IADL and QBPDS increased, and the intensity of pain decreased. Surgery reduced pain intensity from 8 ± 0.8 to 6.1 ± 1.4 points. The level of self-esteem (RSES) remained at a low level. The passage of time after neurosurgical treatment has a beneficial effect on reducing pain intensity and increasing independence in life activities. Daily physical activity and rehabilitation are important factors supporting the return to independence. Full article

Additional interpretations of Genesis 3:16 have often translated God’s words to the woman as a punishment, even a curse, brought upon the woman as the result of her disobedience. Moreover, this so-called curse of the woman has been read by many interpreters as final and irreversible, given that God himself had decreed it. Interestingly, however, no curse is uttered at all in this passage. Moreover, Genesis 3:16 is itself preceded by a divine blessing, given in Genesis 1 to the human couple. As a blessing, it constitutes a divine decree that can neither be overturned nor challenged. The purpose of this essay will be to go back to this divine blessing in Genesis 1, knowing that such a decree will be irrevocable no matter what the future holds for the human couple. This will in turn shed a revealing light on how we are to read and interpret Genesis 3:16. Not only do the words of God to the woman in Genesis 3:16 not constitute a curse, but Genesis 3:16 must be read against the backdrop of the blessing given in Genesis 1. This of course radically alters how this passage has hereto been interpreted as well as profoundly nuances its teaching on gender relations. Full article

The ability to recognize the body sizes of sheep is significantly influenced by posture, especially without artificial fixation, leading to more noticeable changes. This study presents a recognition model using the Mask R-CNN convolutional neural network to identify the sides and backs of sheep. The proposed approach includes an algorithm for extracting key frames through mask calculation and specific algorithms for head-down, head-up, and jumping postures of Ujumqin sheep. The study reported an accuracy of 94.70% in posture classification. We measured the body size parameters of Ujumqin sheep of different sexes and in different walking states, including observations of head-down and head-up. The errors for the head-down position of rams, in terms of body slanting length, withers height, hip height, and chest depth, were recorded as 0.08 ± 0.06, 0.09 ± 0.07, 0.07 ± 0.05, and 0.12 ± 0.09, respectively. For rams in the head-up position, the corresponding errors were 0.06 ± 0.05, 0.06 ± 0.05, 0.07 ± 0.05, and 0.13 ± 0.07, respectively. The errors for the head-down position of ewes, in terms of body slanting length, withers height, hip height, and chest depth, were recorded as 0.06 ± 0.05, 0.09 ± 0.08, 0.07 ± 0.06, and 0.13 ± 0.10, respectively. For ewes in the head-up position, the corresponding errors were 0.06 ± 0.05, 0.08 ± 0.06, 0.06 ± 0.04, and 0.16 ± 0.12, respectively. The study observed that sheep walking through a passage exhibited a more curved knee posture compared to normal measurements, often with a lowered head. This research presents a cost-effective data collection scheme for studying multiple postures in animal husbandry. Full article

Biogenic polyamines are ubiquitous compounds. Dysregulation of their metabolism is associated with the development of various pathologies, including cancer, hyperproliferative diseases, and infections. The canonical pathway of polyamine catabolism includes acetylation of spermine and spermidine and subsequent acetylpolyamine oxidase (PAOX)-mediated oxidation of acetylpolyamines (back-conversion) or their direct efflux from the cell. PAOX is considered to catalyze a non-rate-limiting catabolic step. Here, we show that PAOX transcription levels are extremely low in various tumor- and non-tumor cell lines and, in most cases, do not change in response to altered polyamine metabolism. Its enzymatic activity is undetectable in the majority of cell lines except for neuroblastoma and low passage glioblastoma cell lines. Treatment of A549 cells with N¹,N¹¹-diethylnorspermine leads to PAOX induction, but its contribution to polyamine catabolism remains moderate. We also describe two alternative enzyme isoforms and show that isoform 4 has diminished oxidase activity and isoform 2 is inactive. PAOX overexpression correlates with the resistance of cancer cells to genotoxic antitumor drugs, indicating that PAOX may be a useful therapeutic target. Finally, PAOX is dispensable for the replication of various viruses. These data suggest that a decrease in polyamine levels is achieved predominantly by the secretion of acetylated spermine and spermidine rather than by back-conversion. Full article

The standard multi-dose nasal spray pump features an integrated actuator and nozzle, which inevitably causes a retraction of the nozzle tip during application. The retraction stroke is around 5.5 mm and drastically reduces the nozzle’s insertion depth, which further affects the initial nasal spray deposition and subsequent translocation, potentially increasing drug wastes and dosimetry variability. To address this issue, we designed a new spray pump that separated the nozzle from the actuator and connected them with a flexible tube, thereby eliminating nozzle retraction during application. The objective of this study is to test the new device’s performance in comparison to the conventional nasal pump in terms of spray generation, plume development, and dosimetry distribution. For both devices, the spray droplet size distribution was measured using a laser diffraction particle analyzer. Plume development was recorded with a high-definition camera. Nasal dosimetry was characterized in two transparent nasal cavity casts (normal and decongested) under two breathing conditions (breath-holding and constant inhalation). The nasal formulation was a 0.25% w/v methyl cellulose aqueous solution with a fluorescent dye. For each test case, the temporospatial spray translocation in the nasal cavity was recorded, and the final delivered doses were quantified in five nasal regions. The results indicate minor differences in droplet size distribution between the two devices. The nasal plume from the new device presents a narrower plume angle. The head orientation, the depth at which the nozzle is inserted into the nostril, and the administration angle play crucial roles in determining the initial deposition of nasal sprays as well as the subsequent translocation of the liquid film/droplets. Quantitative measurements of deposition distributions in the nasal models were augmented with visualization recordings to evaluate the delivery enhancements introduced by the new device. With an extension tube, the modified device produced a lower spray output and delivered lower doses in the front, middle, and back turbinate than the conventional nasal pump. However, sprays from the new device were observed to penetrate deeper into the nasal passages, predominantly through the middle-upper meatus. This resulted in consistently enhanced dosing in the middle-upper turbinate regions while at the cost of higher drug loss to the pharynx. Full article

This study explores the possibility of designing simple semitransparent antennas that allow for the passage of most visible light while maintaining good electromagnetic performance. We propose a substrateless metal mesh patch antenna manufactured using low-cost 3D printing and silver conductive paint. Our goal is to integrate numerous such radiators onto office building windows, preserving natural lighting with minimal visual impact, aiming to alleviate infrastructure congestion or improve antenna placement in sub-6 GHz frequency bands. In this paper, we conduct an analysis of the primary parameters influencing patches constructed with substrateless metal mesh wires, focusing on the grid topology and the width of the metallic wires, as well as their effects on antenna transparency and back radiation. Owing to the absence of a substrate, the antenna demonstrates minimal losses. Furthermore, in this study, we thoroughly investigate the effects of conductivity and roughness on surfaces printed with metallic paint. A prototype at 2.6 GHz is presented, achieving over 60% transparency, a 2.7% impedance-matching bandwidth, and a realized peak gain of 5.4 dBi. The antenna is easy to manufacture and cost-effective and considers sustainability. Its large-scale implementation can alleviate building infrastructure, enhancing radio connectivity in urban environments and offering new cost-effective and energy-efficient wireless solutions. Full article

Wine has a rich history dating back to 2200 BC, originally recognized for its medicinal properties. Today, with the aid of advanced technologies like metabolomics and sophisticated analytical techniques, we have gained remarkable insights into the molecular-level changes induced by wine consumption in the human organism. This review embarks on a comprehensive exploration of the alterations in human metabolome associated with wine consumption. A great number of 51 studies from the last 25 years were reviewed; these studies systematically investigated shifts in metabolic profiles within blood, urine, and feces samples, encompassing both short-term and long-term studies of the consumption of wine and wine derivatives. Significant metabolic alterations were observed in a wide variety of metabolites belonging to different compound classes, such as phenolic compounds, lipids, organic acids, and amino acids, among others. Within these classes, both endogenous metabolites as well as diet-related metabolites that exhibited up-regulation or down-regulation following wine consumption were included. The up-regulation of short-chain fatty acids and the down-regulation of sphingomyelins after wine intake, as well as the up-regulation of gut microbial fermentation metabolites like vanillic and syringic acid are some of the most important findings reported in the reviewed literature. Our results confirm the intact passage of certain wine compounds, such as tartaric acid and other wine acids, to the human organism. In an era where the health effects of wine consumption are of growing interest, this review offers a holistic perspective on the metabolic underpinnings of this centuries-old tradition. Full article

Background: This project originated from the study of an 18th century manuscript found in Valle Imagna (Bergamo, Italy) which contains 200 plant-based medicinal remedies. A first comparison with published books concerning 20th century folk medicine in the Valley led to the designing of an ethnobotanical investigation, aimed at making a thorough comparison between past and current phytotherapy knowledge in this territory. Methods: The field investigation was conducted through semi-structured interviews. All data collected was entered in a database and subsequently processed. A diachronic comparison between the field results, the manuscript, and a 20th century book was then performed. Results: A total of 109 interviews were conducted and the use of 103 medicinal plants, belonging to 46 families, was noted. A decrease in number of plant taxa and uses was observed over time, with only 42 taxa and 34 uses reported in the manuscript being currently known by the people of the valley. A thorough comparison with the remedies in the manuscript highlighted similar recipes for 12 species. Specifically, the use of agrimony in Valle Imagna for the treatment of deep wounds calls back to an ancient remedy against leg ulcers based on this species. Conclusions: The preliminary results of this study allow us to outline the partial passage through time fragments of ancient plant-based remedies once used in the investigated area. Full article

The determination of soil parameters in geotechnical engineering and their variations during the construction process have long been a focal point for engineering designers. While the artificial neural network (ANN) has been employed for back analysis of soil parameters, its application to caisson sinking processes remains limited. This study focuses on the Nanjing Longtan Yangtze River Bridge project, specifically the south anchoring of an ultra-large rectangular caisson. A comprehensive analysis of the sinking process was conducted using 400 finite element method (FEM) models to obtain the structural stress and earth pressure at key locations. Multiple combinations of soil parameters were considered, resulting in a diverse set of simulation results. These results were then utilized as training samples to develop a back-propagating artificial neural network (BP ANN), which utilized the structural stress and earth pressure as input sets and the soil parameters as output sets. The BP ANN was individually trained for each stage of the sinking process. Subsequently, the trained ANN was employed to predict the soil parameters under different working conditions based on actual monitoring data from engineering projects. The obtained soil parameter variations were further analyzed, leading to the following conclusions: (1) The soil parameters estimated by the ANN exhibited strong agreement with the original values from the geological survey report, validating their reliability; (2) The surrounding soil during the caisson sinking exhibited three distinct states: a stable state prior to the arrival of the cutting edges, a strengthened state upon the arrival of the cutting edges, and a disturbed state after the passage of the cutting edges; (3) In the stable state, the soil parameters closely resembled the original values, whereas in the strengthened state, the soil strength and stiffness significantly increased, while the Poisson’s ratio decreased. In the disturbed state, the soil strength and stiffness were slightly lower than the original values. This study represents a valuable exploration of back analysis for caisson engineering. The findings provide important insights for similar engineering design and construction projects. Full article

The Consolation of Philosophy by Boethius was not only widely read during the Middle Ages, but it was also frequently glossed, commented on, and discussed. The ninth poem of the third book, which offers a Platonic image of the creation of the cosmos and the governance over it, had a specific place in the reception of this Boethius’s work. Today we know of numerous debates about the possible interpretations of this poem and its Christian understanding, dating back at least to the 9th century. This paper deals with the commentary on this poem written by Adalbold of Utrecht († 1026). Attention is focused in particular on the role of dialectic in selected passages of this Adalbold’s text and on the inspirational sources of his dialectical knowledge. Specifically, the paper deals with the possibility of definition or description of God (Deus sine nomine), and arguments explaining the appropriateness or inappropriateness of conceptualizing God as the form of the highest good (forma summi boni). Full article

Recent field data suggest that migratory gulls disperse many rice field weeds by gut passage (endozoochory), most of which are dry fruited and widely assumed to have no long-distance dispersal mechanisms, except via human activity. We investigated this mechanism with a feeding experiment, in which seeds of five common rice field weeds (in order of increasing seed size: Juncus bufonius, Cyperus difformis, Polypogon monspeliensis, Amaranthus retroflexus, and the fleshy-fruited Solanum nigrum) were fed to seven individuals of lesser black-backed gulls Larus fuscus held in captivity. We quantified seed survival after collecting faeces at intervals for 33 h after ingestion, then extracting intact seeds and running germination tests, which were also conducted for control seeds. All five species showed high seed survival after gut passage, of >70%. Gut retention times averaged 2–4 h, but maxima exceeded 23 h for all species. Germinability after gut passage was 16–54%, and gut passage accelerated germination in J. bufonius and S. nigrum, but slowed it down in the other species. All species had lower germinability after gut passage compared to control seeds (likely due to stratification prior to the experiment), but the loss of germinability was higher in smaller seeds. There was no evidence that the different dispersal syndromes assigned to the five species (endozoochory, epizoochory or barochory) had any influence on our results. In contrast, mean gut retention time was strongly and positively related to seed size, likely because small seeds pass more quickly from the gizzard into the intestines. Non-classical endozoochory of dry-fruited seeds by waterbirds is a major but overlooked mechanism for potential long-distance dispersal, and more research into this process is likely essential for effective weed management. Full article

Various studies have shown that the transmission and passage of alien and native pathogens play a critical role in the establishment process of an invasive species and its further spread. Egyptian geese (Alopochen aegyptiaca) are neozotic birds on various continents. They live not only in the countryside near fresh water bodies but also in urban habitats in Central Europe with close contact to humans and their pets. Although their rapid distribution in Europe is widely debated, scientific studies on the anthropozoonotic risks of the population and studies on the present endoparasites in Egyptian geese are rare worldwide. In the present study, 114 shot Egyptian geese and 148 non-invasively collected faecal samples of wild Egyptian geese from 11 different Federal States in Germany were examined. A total of 13 metazoan endoparasite species in 12 different genera were identified. The main endoparasites found were Hystrichis tricolor, Polymorphus minutus, and, in lesser abundance, Cloacotaenia sp. and Echinuria uncinata. Adult stages of Echinostoma revolutum, an anthropozoonotic heteroxenic trematode, were found in 7.9% of the animals examined postmortem. This species was additionally identified by molecular analysis. Although Egyptian geese live in communities with native waterfowl, it appears that they have a lower parasitic load in general. The acquisition of generalistic parasites in an alien species and the associated increased risk of infection for native species is known as “spill-back” and raises the question of impacts on native waterfowl. Differences between animals from rural populations and urban populations were observed. The present study represents the first large-scale survey on gastrointestinal parasites of free-ranging Egyptian geese. Full article

Vimalamitra’s (ca. the 8th–9th cent.) *Āryaprajñāpāramitāhṛdayaṭīkā (hereafter the PHT) sparks interest not only because of its detailed verbal commentary on the Prajñāpāramitāhṛdaya or the Heart Sūtra but also because it developed various philosophical arguments. However, these arguments have not always been clear due to the difficulty surrounding Tibetan translation and the complexity of the discussion. For instance, in 2021, Mathes, who examined some passages of the PHT, suggested that Vimalamitra endorsed the Yogācāra idea that the perfect nature exists ultimately as the dharmakāya—an idea that can be traced back to 1996, Lopez. However, a close reading of the relevant passages of the PHT through consultation with the commentary on the Saptaśatikā Prajñāpāramitā by Vimalamitra himself, a sub-commentary on the PHT by rNgog blo ldan shes rab (1059–1109), and a reading of the Tibetan translation (the only translation preserved) conjecturing the underlying original Sanskrit reveals that the opposite is true: there is a fierce and complex debate between Madhyamaka and Yogācāra on the passage, with Vimalamitra sharply criticizing the latter’s views as a Mādhyamika. Thus, this paper will reveal for the first time the previously unknown details of the dispute between Yogācāra and Madhyamaka in the PHT. This will offer new evidence for the confrontation between the two around the eighth and ninth centuries. Full article