Search Results (18,216)

This study is concerned with the restoration of painted pottery images from the Yangshao period. The objective is to enhance the efficiency and accuracy of the restoration process for complex pottery patterns. Conventional restoration techniques encounter difficulties in accurately and efficiently reconstructing intricate designs. To address this issue, the study proposes an AI-assisted restoration workflow that combines Stable Diffusion models (SD) with Low-Rank Adaptation (LoRA) technology. By training a LoRA model on a dataset of typical Yangshao painted pottery patterns and integrating image inpainting techniques, the accuracy and efficiency of the restoration process are enhanced. The results demonstrate that this method provides an effective restoration tool while maintaining consistency with the original artistic style, supporting the digital preservation of cultural heritage. This approach also offers archaeologists flexible restoration options, promoting the broader application and preservation of cultural heritage. Full article

Valley path planning on 3D terrains holds significant importance in navigating and understanding complex landscapes. This specialized form of path planning focuses on finding optimal routes that adhere to the natural contours of valleys within three-dimensional terrains. The significance of valley path planning lies in its ability to address specific challenges presented by valleys, such as varying depths, steep slopes, and potential obstacles. By following the natural flow of valleys, path planning can enhance the efficiency of navigation and minimize the risk of encountering difficult terrain or hazards. In recent years, an increasing number of researchers have focused on the study of valley path planning on 3D terrains. This study presents a valley path planning method utilizing the NSGA-II (Non-dominated Sorting Genetic Algorithm II) approach. To ensure that the paths generated by the algorithm closely follow the valley lines, the algorithm establishes an optimization function that includes three optimization criteria: mean altitude, flight route length, and mean offset. To test the performance of this algorithm, we conducted experiments based on workspaces based on three datasets full of 3D terrains and compared it with three baseline algorithms. The evaluation indicates that the suggested algorithm successfully designs routes that closely follow the valley contours. Full article

Background: Obstructive sleep apnea is a sleep disorder that is linked to many health complications and can even be lethal in its severe form. Overnight polysomnography is the gold standard for diagnosing apnea, which is expensive, time-consuming, and requires manual analysis by a sleep expert. Artificial intelligence (AI)-embedded wearable device as a portable and less intrusive monitoring system is a highly desired alternative to polysomnography. However, AI models often require substantial storage capacity and computational power for edge inference which makes it a challenging task to implement the models in hardware with memory and power constraints. Methods: This study demonstrates the implementation of depth-wise separable convolution (DSC) as a resource-efficient alternative to spatial convolution (SC) for real-time detection of apneic activity. Single lead electrocardiogram (ECG) and oxygen saturation (SpO₂) signals were acquired from the PhysioNet databank. Using each type of convolution, three different models were developed using ECG, SpO₂, and model fusion. For both types of convolutions, the fusion models outperformed the models built on individual signals across all the performance metrics. Results: Although the SC-based fusion model performed the best, the DSC-based fusion model was 9.4, 1.85, and 11.3 times more energy efficient than SC-based ECG, SpO₂, and fusion models, respectively. Furthermore, the accuracy, precision, and specificity yielded by the DSC-based fusion model were comparable to those of the SC-based individual models (~95%, ~94%, and ~94%, respectively). Conclusions: DSC is commonly used in mobile vision tasks, but its potential in clinical applications for 1-D signals remains unexplored. While SC-based models outperform DSC in accuracy, the DSC-based model offers a more energy-efficient solution with acceptable performance, making it suitable for AI-embedded apnea detection systems. Full article

In the face of constantly changing cyber threats, a variety of actions, tools, and regulations must be considered to safeguard information assets and guarantee the confidentiality, reliability, and availability of digital resources. The purpose of this research is to create an artificial intelligence (AI)-driven system to enhance sustainability for cyber threat detection in Internet of Things (IoT) environments. This study proposes a modern technique named Artificial Fish Swarm-driven Weight-normalized Adaboost (AF-WAdaBoost) for optimizing accuracy and sustainability in identifying attacks, thus contributing to heightening security in IoT environments. CICIDS2017, NSL-KDD, and UNSW-NB15 were used in this study. Min-max normalization is employed to pre-process the obtained raw information. The proposed model AF-WAdaBoost dynamically adjusts classifiers, enhancing accuracy and resilience against evolving threats. Python is used for model implementation. The effectiveness of the suggested AF-WAdaBoost model in identifying different kinds of cyber-threats in IoT systems is examined through evaluation metrics like accuracy (98.69%), F-measure (94.86%), and precision (95.72%). The experimental results unequivocally demonstrate that the recommended model performed better than other traditional approaches, showing essential enhancements in accuracy and strength, particularly in a dynamic environment. Integrating AI-driven detection balances offers sustainability in cybersecurity, ensuring the confidentiality, reliability, and availability of information assets, and also helps in optimizing the accuracy of systems. Full article

The issue of sustainability has emerged as a focal point within the museum sector. This article aims to investigate the perceptions and attitudes of Chinese general visitors towards museums and sustainability. To achieve this, we employed a visitor evaluation approach, with inhabitants of the Chinese mainland serving as the target population. We conducted a survey using an online questionnaire, yielding a total of 1260 valid samples. The study finds that most museum visitors in mainland China see a strong link between museums and sustainable development, with factors like age, gender, education, familiarity with sustainable development, and museum interaction shaping these perceptions. The results indicate that large segments of the Chinese visitors hold a favourable perception of the significance of museums in terms of environmental, social, economic, and cultural sustainability. However, the visitor generally does not wish to sacrifice their own visiting experience to enhance museums’ sustainable development capacities. The article examines the relationship between museums and sustainability and offers recommendations for museum practice and policymaking in China and beyond. Full article

Background: As the demand for early and accurate diagnosis of autism spectrum disorder (ASD) increases, the integration of machine learning (ML) and explainable artificial intelligence (XAI) is emerging as a critical advancement that promises to revolutionize intervention strategies by improving both accuracy and transparency. Methods: This paper presents a method that combines XAI techniques with a rigorous data-preprocessing pipeline to improve the accuracy and interpretability of ML-based diagnostic tools. Our preprocessing pipeline included outlier removal, missing data handling, and selecting pertinent features based on clinical expert advice. Using R and the caret package (version 6.0.94), we developed and compared several ML algorithms, validated using 10-fold cross-validation and optimized by grid search hyperparameter tuning. XAI techniques were employed to improve model transparency, offering insights into how features contribute to predictions, thereby enhancing clinician trust. Results: Rigorous data-preprocessing improved the models’ generalizability and real-world applicability across diverse clinical datasets, ensuring a robust performance. Neural networks and extreme gradient boosting models achieved the best performance in terms of accuracy, precision, and recall. XAI techniques demonstrated that behavioral features significantly influenced model predictions, leading to greater interpretability. Conclusions: This study successfully developed highly precise and interpretable ML models for ASD diagnosis, connecting advanced ML methods with practical clinical application and supporting the adoption of AI-driven diagnostic tools by healthcare professionals. This study’s findings contribute to personalized intervention strategies and early diagnostic practices, ultimately improving outcomes and quality of life for individuals with ASD. Full article

The application of AI (Artificial Intelligence) in emergency medicine helps significantly improve the quality of diagnostics under limitations of resources and time constraints in emergency cases. We have designed a comprehensive AI-based diagnostic and treatment plan decision-support system for emergency medicine by integrating the available LLMs (Large Language Models), like ChatGPT, Gemini, Claude, and others, and tuning them up with additional training on actual emergency cases. There is a special focus on early detection of life-threatening and time-sensitive diseases like sepsis, stroke, and heart attack, which are the major causes of death in emergency medicine. Additional training was conducted on a total of 600 cases (300 sepsis; 300 non-sepsis). The collective capability of the integrated LLMs is much stronger than each individual engine. Emergency cases can be predicted based on information from multiple sensors and streaming sources combining traditional IT (Information Technology) infrastructure with Internet of Things (IoT) schemes. Medical personnel compare and validate the AI models used in this work. Full article

Fuzzy systems are powerful modeling systems for uncertainty applications. In contrast to traditional crisp systems, fuzzy systems offer the opportunity to extend the binary decision to continuous space, which could offer benefits for various application areas such as intrusion detection systems (IDSs), because of their ability to measure the degree of attacks instead of making a binary decision. Furthermore, fuzzy systems offer a suitable environment that is able to deal with uncertainty. However, fuzzy systems face a critical challenge represented by the sparse fuzzy rules. Typical fuzzy systems demand complete fuzzy rules in order to offer the required results. Additionally, generating complete fuzzy rules can be difficult due to many factors, such as a lack of knowledge base or limited data availability, such as in IDS applications. Fuzzy rule interpolation (FRI) was introduced to overcome this limitation by generating the required interpolation results in cases with sparse fuzzy rules. This work introduces a threefold approach designed to address the cases of missing fuzzy rules, which uses a few fuzzy rules to handle the limitations of missing fuzzy rules. This is achieved by finding the interpolation condition of neighboring fuzzy rules. This procedure was accomplished based on the concept of factors (which determine the degree to which each neighboring fuzzy rule contributes to the interpolated results, in cases of missing fuzzy rules). The evaluation procedure for the threefold approach was conducted using the following two steps: firstly, using the FRI benchmark numerical metrics, the results demonstrated the ability of the threefold approach to generate the required results for the various benchmark scenarios. Secondly, using a real-life dataset (phishing attacks dataset), the results demonstrated the effectiveness of the suggested approach to handle cases of missing fuzzy rules in the area of phishing attacks. Consequently, the suggested threefold approach offers an opportunity to reduce the number of fuzzy rules effectively and generate the required results using only a few fuzzy rules. Full article

Understanding the structures of noncoding RNAs (ncRNAs) is important for the development of RNA-based therapeutics. There are inherent challenges in employing current experimental techniques to determine the tertiary (3D) structures of RNAs with high complexity and flexibility in folding, which makes computational methods indispensable. In this study, we compared the utilities of three advanced computational tools, namely RNAComposer, Rosetta FARFAR2, and the latest AlphaFold 3, to predict the 3D structures of various forms of RNAs, including the small interfering RNA drug, nedosiran, and the novel bioengineered RNA (BioRNA) molecule showing therapeutic potential. Our results showed that, while RNAComposer offered a malachite green aptamer 3D structure closer to its crystal structure, the performances of RNAComposer and Rosetta FARFAR2 largely depend upon the secondary structures inputted, and Rosetta FARFAR2 predictions might not even recapitulate the typical, inverted “L” shape tRNA 3D structure. Overall, AlphaFold 3, integrating molecular dynamics principles into its deep learning framework, directly predicted RNA 3D structures from RNA primary sequence inputs, even accepting several common post-transcriptional modifications, which closely aligned with the experimentally determined structures. However, there were significant discrepancies among three computational tools in predicting the distal loop of human pre-microRNA and larger BioRNA (tRNA fused pre-miRNA) molecules whose 3D structures have not been characterized experimentally. While computational predictions show considerable promise, their notable strengths and limitations emphasize the needs for experimental validation of predictions besides characterization of more RNA 3D structures. Full article

Breast cancer is the most prevalent cancer worldwide, affecting both low- and middle-income countries, with a growing number of cases. In 2024, about 310,720 women in the U.S. are projected to receive an invasive breast cancer diagnosis, alongside 56,500 cases of ductal carcinoma in situ (DCIS). Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. About 65% of women with the BRCA1 and 45% with the BRCA2 gene variants develop breast cancer by age 70. While these genes account for 5% of breast cancers, their prevalence is higher in certain populations. Advances in early detection, personalised medicine, and AI-driven diagnostics are improving outcomes by enabling a more precise analysis, reducing recurrence, and minimising treatment side effects. Our paper aims to explore the vast applications of artificial intelligence within the diagnosis and treatment of breast cancer and how these advancements can contribute to elevating patient care as well as discussing the potential drawbacks of such integrations into modern medicine. We structured our paper as a non-systematic review and utilised Google Scholar and PubMed databases to review literature regarding the incorporation of AI in the diagnosis and treatment of non-palpable breast masses. AI is revolutionising breast cancer management by enhancing imaging, pathology, and personalised treatment. In imaging, AI can improve the detection of cancer in mammography, MRIs, and ultrasounds, rivalling expert radiologists in accuracy. In pathology, AI enhances biomarker detection, improving HER2 and Ki67 assessments. Personalised medicine benefits from AI’s predictive power, aiding risk stratification and treatment response. AI also shows promise in triple-negative breast cancer management, offering better prognosis and subtype classification. However, challenges include data variability, ethical concerns, and real-world validation. Despite limitations, AI integration offers significant potential in improving breast cancer diagnosis, prognosis, and treatment outcomes. Full article

The prediction of the chemical oxygen demand (COD) and total nitrogen (TN) in integrated anaerobic–anoxic–oxic (A2O) and anoxic–oxic (AO) processes (i.e., A2O+AO process) was achieved using a dynamic ensemble model that reflects the dynamics of wastewater treatment plants (WWTPs). This model effectively captures the variability in the influent characteristics and fluctuations within each reactor of the A2O+AO process. By employing a time-lag approach based on the hydraulic retention time (HRT), artificial intelligence (AI) selects suitable input (i.e., pH, temperature, total dissolved solid (TDS), NH₃-N, and NO₃-N) and output (COD and TN) data pairs for training, minimizing the error between predicted and observed values. Data collected over two years from the actual A2O+AO process were utilized. The ensemble model adopted machine learning-based XGBoost for COD and TN predictions. The dynamic ensemble model outperformed the static ensemble model, with the mean absolute percentage error (MAPE) for the COD ranging from 9.5% to 15.2%, compared to the static ensemble model’s range of 11.4% to 16.9%. For the TN, the dynamic model’s errors ranged from 9.4% to 15.5%, while the static model showed lower errors in specific reactors, particularly in the anoxic and oxic stages due to their stable characteristics. These results indicate that the dynamic ensemble model is suitable for predicting water quality in WWTPs, especially as variability may increase due to external environmental factors in the future. Full article

Intelligent Robotic Process Automation (IRPA) combines Artificial Intelligence (AI) and Robotic Process Automation (RPA) to automate complex unstructured tasks, improve decision-making, and cope with changing scenarios. A process analysis framework for IRPA adoption was developed by identifying key factors through a literature review and semi-structured expert opinion survey. The employed experts in the survey comprised RPA/IRPA consultants, RPA/IRPA initiative team leaders, and RPA/IRPA developers with three years or more experience. For the initial factor collection phase, there were a total of eighteen (18) responses, and for the factor evaluation phase, a total of twenty-six (26) experts were used to collect responses. Identified factors were shortlisted and evaluated using a Relative Importance Index (RII) analysis. The study’s findings are presented through a Causal-Loop Diagram (CLD) to illustrate the relationships between factors. The framework provides practical guidance for organizations planning to adopt IRPA, informing decision-making, resource allocation, and strategy development. The final process analysis framework highlights the importance of accuracy, level of human involvement in a task, and standardization as the main three primary factors for successful IRPA adoption. Three major secondary factors were identified: digital data input, integration with existing systems, and the cost of adopting new technologies. This research contributes to the added value to existing knowledge and serves as a foundation for future research in IRPA adoption. Full article

This study evaluates the potential of an AI-based computer-aided detection (AI-CAD) system in digital mammography for predicting pathologic complete response (pCR) in breast cancer patients after neoadjuvant chemotherapy (NAC). A retrospective analysis of 132 patients who underwent NAC and surgery between January 2020 and December 2022 was performed. Pre- and post-NAC mammograms were analyzed using conventional CAD and AI-CAD systems, with negative exams defined by the absence of marked abnormalities. Two radiologists reviewed mammography, ultrasound, MRI, and diffusion-weighted imaging (DWI). Concordance rates between CAD and AI-CAD were calculated, and the diagnostic performance, including the area under the receiver operating characteristics curve (AUC), was assessed. The pre-NAC concordance rates were 90.9% for CAD and 97% for AI-CAD, while post-NAC rates were 88.6% for CAD and 89.4% for AI-CAD. The MRI had the highest diagnostic performance for pCR prediction, with AI-CAD performing comparably to other modalities. Univariate analysis identified significant predictors of pCR, including AI-CAD, mammography, ultrasound, MRI, histologic grade, ER, PR, HER2, and Ki-67. In multivariable analysis, negative MRI, histologic grade 3, and HER2 positivity remained significant predictors. In conclusion, this study demonstrates that AI-CAD in digital mammography shows the potential to examine the pCR of breast cancer patients following NAC. Full article

Corticotropin-releasing hormone (CRH) neurons within the paraventricular hypothalamic nucleus (PVH) play a crucial role in initiating the neuroendocrine response to stress and are also pivotal in coordination of autonomic, metabolic, and behavioral stress reactions. Although the role of parvocellular CRH^PVH neurons in activation of the hypothalamic–pituitary–adrenal (HPA) axis is well established, the distribution and function of CRH-expressing neurons across the whole central nervous system are less understood. Stress responses activate complex neural networks, which differ depending on the type of stressor and on the sex of the individual. Because of the technical difficulties of localizing CRH neurons throughout the rodent brain, several CRH reporter mouse lines have recently been developed. In this study, we used Crh-IRES-Cre;Ai9 reporter mice to examine whether CRH neurons are recruited in a stressor- or sex-specific manner, both within and outside the hypothalamus. In contrast to the clear sexual dimorphism of CRH-mRNA-expressing neurons, quantification of CRH-reporting, tdTomato-positive neurons in different stress-related brain areas revealed only subtle differences between male and female subjects. These results strongly imply that sex differences in CRH mRNA expression occur later in development under the influence of sex steroids and reflects the limitations of using genetic reporter constructs to reveal the current physiological/transcriptional status of a specific neuron population. Next, we compared the recruitment of stress-related, tdTomato-expressing (putative CRH) neurons in male and female Crh-IRES-Cre;Ai9 reporter mice that had been exposed to predator odor. In male mice, fox odor triggered more c-Fos in the CRH neurons of the paraventricular hypothalamic nucleus, central amygdala, and anterolateral bed nucleus of the stria terminalis compared to females. These results indicate that male mice are more sensitive to predator exposure due to a combination of hormonal, environmental, and behavioral factors. Full article

Maternal mortality (MM) is considered one of the major worldwide concerns. Despite the advances of artificial intelligence (AI) in healthcare, the lack of transparency in AI models leads to reluctance to adopt them. Employing explainable artificial intelligence (XAI) thus helps improve the transparency and effectiveness of AI-driven healthcare solutions. Accordingly, this article proposes a complete framework integrating an Internet of Medical Things (IoMT) architecture with an XAI-based deep learning model. The IoMT system continuously monitors pregnant women’s vital signs, while the XAI model analyzes the collected data to identify risk factors and generate actionable insights. Additionally, an efficient IoMT transmission model is developed to ensure reliable data transfer with the best-required system quality of service (QoS). Further analytics are performed on the data collected from different regions in a country to address high-risk cities. The experiments demonstrate the effectiveness of the proposed framework by achieving an accuracy of 80% for patients and 92.6% for regional risk prediction and providing interpretable explanations. The XAI-generated insights empower healthcare providers to make informed decisions and implement timely interventions. Furthermore, the IoMT transmission model ensures efficient and secure data transfer. Full article