Dynamin-Related Protein 1 at the Crossroads of Cancer
Abstract
:1. Introduction
2. Regulation of Dynamin-Related Protein 1 and Its Central Role in Mitochondrial Fission
3. Dynamin-Related Protein 1 and Cell Death
4. Dynamin-Related Protein 1 and Metabolic Reprogramming
5. Dynamin-Related Protein 1 and the Cell Cycle
6. Dynamin-Related Protein 1 Expression and its Role in Tumorigenesis
7. Role of Mitochondrial Dynamics in Invasion and Metastization
8. Future Perspectives and Clinical Implications
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Cell Process | Effects |
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Cell Death |
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Metabolic Reprogramming |
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Response to hypoxic conditions: | |
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Response to starvation: | |
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Cell Cycle | |
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Tumor Model | DRP1 Expression Pattern and Tumorigenic Effects |
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Melanoma |
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Lung Cancer | |
Breast Cancer | |
Thyroid Cancer | |
Type I Endometrial Cancer |
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Epithelial Ovarian Cancer | |
Neuroblastoma |
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Glioblastoma |
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Lima, A.R.; Santos, L.; Correia, M.; Soares, P.; Sobrinho-Simões, M.; Melo, M.; Máximo, V. Dynamin-Related Protein 1 at the Crossroads of Cancer. Genes 2018, 9, 115. https://doi.org/10.3390/genes9020115
Lima AR, Santos L, Correia M, Soares P, Sobrinho-Simões M, Melo M, Máximo V. Dynamin-Related Protein 1 at the Crossroads of Cancer. Genes. 2018; 9(2):115. https://doi.org/10.3390/genes9020115
Chicago/Turabian StyleLima, Ana Rita, Liliana Santos, Marcelo Correia, Paula Soares, Manuel Sobrinho-Simões, Miguel Melo, and Valdemar Máximo. 2018. "Dynamin-Related Protein 1 at the Crossroads of Cancer" Genes 9, no. 2: 115. https://doi.org/10.3390/genes9020115