VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring after Maternal Immune Activation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Breeding
2.3. Pump Implantation
2.4. Behavioral Analysis
2.4.1. Sucrose Preference Test
2.4.2. Tail-Suspension Test
2.4.3. Forced Swim Test (FST)
2.5. Western Blots
2.6. Statistical Analysis
3. Results
3.1. Behavioral Effects of VEGF Infusion
3.2. VEGF Signaling in the Offspring Hippocampus
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Sideromenos, S.; Lindtner, C.; Zambon, A.; Horvath, O.; Berger, A.; Pollak, D.D. VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring after Maternal Immune Activation. Cells 2020, 9, 1048. https://doi.org/10.3390/cells9041048
Sideromenos S, Lindtner C, Zambon A, Horvath O, Berger A, Pollak DD. VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring after Maternal Immune Activation. Cells. 2020; 9(4):1048. https://doi.org/10.3390/cells9041048
Chicago/Turabian StyleSideromenos, Spyridon, Claudia Lindtner, Alice Zambon, Orsolya Horvath, Angelika Berger, and Daniela D. Pollak. 2020. "VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring after Maternal Immune Activation" Cells 9, no. 4: 1048. https://doi.org/10.3390/cells9041048