Nepentezin
Изглед
Nepentezin | |||||||||
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Identifikatori | |||||||||
EC broj | 3.4.23.12 | ||||||||
CAS broj | 9073-80-7 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Nepentezin (EC 3.4.23.12, nepentesna aspartička proteinaza, nepentesno kiselinska proteinaza, nepentacin, nepentazin, aspartilna endopeptidaza) je enzim.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Specifičnost je slična pepsinu, ali dodatno se razlažu veze na obe strane ostatka Asp i u Lys-Arg
Ovaj enzim je prisutan u biljkama Nepenthes spp. i Drosera peltata.
Reference
[уреди | уреди извор]- ^ Amagase, S., Nakayama, S. and Tsugita, A. (1969). „Acid protease in Nepenthes. II. Study on the specificty of nepenthesin”. J. Biochem. (Tokyo). 66: 431—439. PMID 5354017.
- ^ Garg, G.K. & Virupaksha, T.K. (1970). „Acid protease from germinated sorghum. 2. Substrate specificity with synthetic peptides and ribonuclease A”. Eur. J. Biochem. 17: 4—12. PMID 5486576.
- ^ Shinano, S. & Fukushima, K. (1971). „Studies on lotus seed protease. Part III. Some physicochemical and enzymic properties”. Agric. Biol. Chem. 35: 1488—1494.
- ^ Amagase, S. (1972). „Digestive enzymes in insectivorous plants. III. Acid proteases in the genus Nepenthes and Drosera peltata”. J. Biochem. (Tokyo). 72: 73—81. PMID 5069751.
- ^ Takahashi, K., Chang, W-J. and Ko, J-S. (1974). „Specific inhibition of acid proteases from brain, kidney, skeletal muscle, and insectivorous plants by diazoacetyl-DL-norleucine methyl ester and by pepstatin”. J. Biochem. (Tokyo). 76: 897—899. PMID 4436292.
- ^ Tökés, Z.A., Woon, W.C. and Chambers, S.M. (1974). „Digestive enzymes secreted by the carnivorous plant Nepenthes macferlani L”. Planta. 119: 39—46. PMID 16526095.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Nepenthesin на US National Library of Medicine Medical Subject Headings (MeSH)