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Axis of ageing: telomeres, p53 and mitochondria
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PubMed
title
Axis of ageing: telomeres, p53 and mitochondria
(English)
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PubMed
main subject
mitochondrion
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author
Ronald A. DePinho
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2
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Ronald A. DePinho
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Crossref
author name string
Ergün Sahin
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1
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language of work or name
English
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publication date
16 May 2012
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published in
Nature Reviews Molecular Cell Biology
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PubMed
volume
13
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PubMed
issue
6
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PubMed
page(s)
397-404
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PubMed
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Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria
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mTOR: from growth signal integration to cancer, diabetes and ageing
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p53 regulates mitochondrial respiration
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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.
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28 September 2017
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways
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28 September 2017
Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
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IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease
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28 September 2017
Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase
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28 September 2017
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
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Short telomeres compromise β-cell signaling and survival
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28 September 2017
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Telomere dysfunction induces metabolic and mitochondrial compromise.
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28 September 2017
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28 September 2017
TOR and ageing: a complex pathway for a complex process.
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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Identifiers
DOI
10.1038/NRM3352
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4270690
Dimensions Publication ID
1029939051
0 references
OpenCitations bibliographic resource ID
4270690
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4270690
PMC publication ID
3718675
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4270690
PubMed publication ID
22588366
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4270690
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