(Q39837656)

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31 January 2020

title

Mitochondrial dysfunction contributes to oncogene-induced senescence (English)

1 reference

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31 January 2020

author

Xavier Deschênes-Simard

4

1 reference

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31 January 2020

Gerardo Ferbeyre

5

1 reference

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31 January 2020

author name string

Olga Moiseeva

1

1 reference

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31 January 2020

Véronique Bourdeau

2

1 reference

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31 January 2020

Antoine Roux

3

1 reference

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31 January 2020

language of work or name

English

0 references

publication date

15 June 2009

1 reference

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Molecular and Cellular Biology

31 January 2020

published in

1 reference

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31 January 2020

volume

29

1 reference

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31 January 2020

issue

16

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31 January 2020

page(s)

4495-4507

1 reference

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Tumor suppressors and cell metabolism: a recipe for cancer growth

31 January 2020

cites work

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Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

22 September 2017

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

22 September 2017

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

22 September 2017

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Oxygen free radicals in cell senescence: are they signal transducers?

22 September 2017

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Mitochondria: more than just a powerhouse

22 September 2017

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Mitochondria: dynamic organelles in disease, aging, and development

22 September 2017

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Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

22 September 2017

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Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

22 September 2017

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

22 September 2017

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

22 September 2017

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

22 September 2017

1 reference

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

22 September 2017

1 reference

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Glycolytic enzymes can modulate cellular life span

22 September 2017

1 reference

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5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

22 September 2017

1 reference

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Regulation of cellular response to oncogenic and oxidative stress by Seladin-1

22 September 2017

1 reference

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Intrinsic tumour suppression

22 September 2017

1 reference

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

22 September 2017

1 reference

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A DNA damage checkpoint response in telomere-initiated senescence

22 September 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

22 September 2017

1 reference

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p53 has a direct apoptogenic role at the mitochondria

22 September 2017

1 reference

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Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts

22 September 2017

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

22 September 2017

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Superoxide activates mitochondrial uncoupling proteins

22 September 2017

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Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

22 September 2017

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The biochemistry of apoptosis

22 September 2017

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Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

22 September 2017

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PML is induced by oncogenic ras and promotes premature senescence

22 September 2017

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

22 September 2017

1 reference

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Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex

22 September 2017

1 reference

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A model for p53-induced apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725737

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase

22 September 2017

1 reference

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Oxidative DNA damage and senescence of human diploid fibroblast cells.

22 September 2017

1 reference

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Cellular targets for transformation by the adenovirus E1A proteins

22 September 2017

1 reference

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Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition

22 September 2017

1 reference

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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

25 September 2017

1 reference

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Differential regulation of antioxidant enzymes in response to oxidants

17 June 2018

1 reference

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Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

17 June 2018

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Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I.

20 August 2018

1 reference

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Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

20 August 2018

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Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

20 August 2018

1 reference

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Transformation of normal human cells in the absence of telomerase activation.

20 August 2018

1 reference

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Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts

20 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19528227

12 December 2020

The tumor-suppressive functions of the human INK4A locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19528227

12 December 2020

Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19528227

12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/19528227

12 December 2020

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19528227

12 December 2020

Identifiers

DOI

10.1128/MCB.01868-08

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528227%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

19528227

1 reference