(Q24299631)

22 June 2017

title

Feedback between p21 and reactive oxygen production is necessary for cell senescence (English)

1 reference

Growth factor receptor bound protein 2

22 June 2017

0 references

0 references

1 reference

Mitogen-activated protein kinase 14

1 reference

Cyclin dependent kinase inhibitor 1A

1 reference

tumor protein p53

1 reference

Transforming growth factor beta receptor 2

1 reference

Growth arrest and DNA damage inducible alpha

1 reference

positive regulation of reactive oxygen species metabolic process

1 reference

1 reference

Glyn Nelson

2

Glyn

Nelson

1 reference

19 October 2023

Cedric Simillion

5

Cedric

Simillion

1 reference

19 October 2023

Carole J Proctor

6

Carole J

Proctor

1 reference

19 October 2023

Gabriele Saretzki

11

Gabriele

Saretzki

1 reference

19 October 2023

Anil Wipat

10

Anil

Wipat

1 reference

19 October 2023

Karl Lenhard Rudolph

12

Karl Lenhard

Rudolph

1 reference

19 October 2023

Thomas von Zglinicki

14

Thomas

von Zglinicki

1 reference

19 October 2023

1

João F Passos

João F

Passos

1 reference

22 June 2017

4

Torsten Richter

Torsten

Richter

1 reference

22 June 2017

7

Satomi Miwa

Satomi

Miwa

1 reference

22 June 2017

8

Sharon Olijslagers

Sharon

Olijslagers

1 reference

22 June 2017

Chunfang Wang

3

Chunfang

Wang

1 reference

22 June 2017

Jennifer Hallinan

series ordinal

9

author given names

Jennifer

author last names

Hallinan

1 reference

22 June 2017

Tom B L Kirkwood

series ordinal

13

author given names

Tom B L

author last names

Kirkwood

1 reference

22 June 2017

language of work or name

English

0 references

publication date

16 February 2010

1 reference

Molecular Systems Biology

22 June 2017

published in

1 reference

22 June 2017

volume

6

1 reference

22 June 2017

page(s)

347

1 reference

describes a project that uses

22 June 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2835567/fullTextXML

inferred from PubMed Central ID database lookup

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

19 March 2017

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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

19 March 2017

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TRF2 Protects Human Telomeres from End-to-End Fusions

19 March 2017

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Chemokine signaling via the CXCR2 receptor reinforces senescence

19 March 2017

1 reference

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Defective DNA repair and neurodegenerative disease

19 March 2017

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Trends in oxidative aging theories

19 March 2017

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The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

19 March 2017

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Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1

19 March 2017

1 reference

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Ink4a/Arf expression is a biomarker of aging

19 March 2017

1 reference

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Cellular senescence: when bad things happen to good cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Restoration of p53 function leads to tumour regression in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Understanding the odd science of aging

7 April 2017

1 reference

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A DNA damage checkpoint response in telomere-initiated senescence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Oxidative stress shortens telomeres

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

p53 mutant mice that display early ageing-associated phenotypes

7 April 2017

1 reference

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The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

DNA damage foci in mitosis are devoid of 53BP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitochondrial dysfunction contributes to oncogene-induced senescence.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Senescence-messaging secretome: SMS-ing cellular stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Telomerase reverse transcriptase delays aging in cancer-resistant mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Living on a break: cellular senescence as a DNA-damage response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Modification of the ATM/ATR directed DNA damage response state with aging and long after hepatocyte senescence induction in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Free radicals and senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

DNA damage signalling guards against activated oncogenes and tumour progression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Vascular cell senescence: contribution to atherosclerosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitochondrial signaling: the retrograde response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Reversal of human cellular senescence: roles of the p53 and p16 pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Redox signaling and the MAP kinase pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Oxidative DNA damage and senescence of human diploid fibroblast cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Microarray analysis of replicative senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Quantitative assessment of markers for cell senescence.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Role of TGF-β1-independent changes in protein neosynthesis, p38αMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

A systematic look at an old problem

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Phospho.ELM: a database of phosphorylation sites--update 2008.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Mitochondria and ageing: winning and losing in the numbers game.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

ROS as a tumour suppressor?

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Cellular senescence in aging primates.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Tools for the SBML Community

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

Multi-parameter analysis of the kinetics of NF-kappaB signalling and transcription in single living cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835567

DNA damage response and cellular senescence in tissues of aging mice

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

p16 INK4a can initiate an autonomous senescence program

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

Towards an e-biology of ageing: integrating theory and data

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

A probabilistic functional network of yeast genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20160708

12 December 2020

Exact stochastic simulation of coupled chemical reactions

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMSB.2010.5

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/MSB.2010.5

1 reference

release_uvvlirhp2vekdmec6iftdakdxe

22 June 2017

Fatcat ID

0 references

OpenCitations bibliographic resource ID

1736738

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1736738

1 reference