Tropomodulin 2: Difference between revisions
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*{{cite journal |author=Pawlak G, McGarvey TW, Nguyen TB, ''et al.'' |title=Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder. |journal=Int. J. Cancer |volume=110 |issue= 3 |pages= 368–73 |year= 2004 |pmid= 15095301 |doi= 10.1002/ijc.20151 }} |
*{{cite journal |author=Pawlak G, McGarvey TW, Nguyen TB, ''et al.'' |title=Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder. |journal=Int. J. Cancer |volume=110 |issue= 3 |pages= 368–73 |year= 2004 |pmid= 15095301 |doi= 10.1002/ijc.20151 }} |
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*{{cite journal |author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |pmc=1356129 }} |
*{{cite journal |author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |pmc=1356129 }} |
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*{{cite journal |author=Watakabe A, Kobayashi R, Helfman DM |title=N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. |journal=J. Cell. Sci. |volume=109 |
*{{cite journal |author=Watakabe A, Kobayashi R, Helfman DM |title=N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. |journal=J. Cell. Sci. |volume=109 |issue= 9|pages= 2299–310 |year= 1996 |pmid= 8886980 |doi= }} |
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*{{cite journal |author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928 }} |
*{{cite journal |author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928 }} |
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*{{cite journal |author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} |
*{{cite journal |author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} |
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Revision as of 09:23, 7 January 2012
Tropomodulin 2 (neuronal) also known as TMOD2 is a protein which in humans is encoded by the TMOD2 gene.[1]
Function
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.[2]
References
- ^ Cox PR, Zoghbi HY (2000). "Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs". Genomics. 63 (1): 97–107. doi:10.1006/geno.1999.6061. PMID 10662549.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ "Entrez Gene: TMOD2 , Tropomodulin 2 (neuronal)".
Further reading
- Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Pawlak G, McGarvey TW, Nguyen TB; et al. (2004). "Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder". Int. J. Cancer. 110 (3): 368–73. doi:10.1002/ijc.20151. PMID 15095301.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Watakabe A, Kobayashi R, Helfman DM (1996). "N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin". J. Cell. Sci. 109 (9): 2299–310. PMID 8886980.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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