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MYL9

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MYL9
Identifiers
AliasesMYL9, LC20, MLC-2C, MLC2, MRLC1, MYRL2, myosin light chain 9, MMIHS4
External IDsOMIM: 609905; MGI: 2138915; HomoloGene: 21230; GeneCards: MYL9; OMA:MYL9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_181526
NM_006097

NM_172118

RefSeq (protein)

NP_006088
NP_852667

NP_742116

Location (UCSC)Chr 20: 36.54 – 36.55 MbChr 2: 156.62 – 156.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene.[5]

Function

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Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101335Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067818Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kumar CC, Mohan SR, Zavodny PJ, Narula SK, Leibowitz PJ (May 1989). "Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells". Biochemistry. 28 (9): 4027–35. doi:10.1021/bi00435a059. PMID 2526655.
  6. ^ "Entrez Gene: myosin".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.