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A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Palskis, Kristaps (Riga Technical University (LV)) ; Tranquille, Gerard Alain (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Sapinski, Mariusz (Paul Scherrer Institute (CH)) ; Taylor, Rebecca Louise (CERN)
Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. [...]
CERN-ACC-NOTE-2022-0018 ; CERN-ACC-NOTE-2022-018 ; NIMMS-Note-010.
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2022. - 4 p.
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A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Benedetto, Elena (U. Geneva (main)) ; Bisoffi, Giovanni (INFN, Legnaro) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Paļskis, Kristaps (CERN) ; Sapinski, Mariusz (PSI, Villigen) ; Taylor, Rebecca (CERN) ; Tranquille, Gerard (CERN)
Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. [...]
2022 - 4 p.
- Published in : JACoW IPAC 2022 (2022) 811-814
Fulltext: PDF;
In : 13th International Particle Accelerator Conference (IPAC 2022), Bangkok, Thailand, 12 - 17 Jun 2022, pp.811-814
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CONCEPTUAL DESIGN OF A COMPACT SYNCHROTRON-BASED FACILITY FOR CANCER THERAPY AND BIOMEDICAL RESEARCH WITH HELIUM AND PROTONS BEAMS
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Taylor, Rebecca (Imperial College (GB)) ; Tranquille, Gerard Alain (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Torims, Toms (Riga Technical University (LV)) ; Palskis, Kristaps (Riga Technical University (LV)) ; Sapinski, Mariusz (Paul Scherrer Institute (CH)) et al.
Thanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams [...]
CERN-ACC-NOTE-2023-0012 ; NIMMS-Note-018.
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2023. - 6 p.
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A novel facility for cancer therapy and biomedical research with heavy ions for the South East European International Institute for Sustainable Technologies
/ Damjanovic, Sanja (SEEIIST Association (CH)) ; Amaldi, Ugo (TERA Foundation (IT)) ; Benedetto, Elena (SEEIIST Association (CH)) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Dosanjh, Manjit ; Durante, Marco ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE)) ; Grubling, Peter (SEEIIST Association (CH)) ; Rossi, Sandro ; Sapinski, Mariusz (SEEIIST Association (CH)) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) proposes the construction of a major joint Research Infrastructure in the region, to rebuild cooperation after the recent wars and overcome lasting consequences like technology deficits and brain drain, having at its core a facility for cancer therapy and biomedical research with heavy ions. [...]
CERN-ACC-NOTE-2021-0019 ; NIMMS-Note-005.
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2021. - 4 p.
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Conceptual design of a compact synchrotron-based facility for cancer therapy and biomedical research with helium and proton beams
/ Vretenar, M (CERN) ; Angoletta, M E (CERN) ; Borburgh, J (CERN) ; Bottura, L (CERN) ; Taylor, R (CERN) ; Tranquille, G (CERN) ; Benedetto, E (Unlisted, CH) ; Torims, T (Latvia U., ISSP) ; Paļskis, K (Latvia U., ISSP) ; Sapinski, M (PSI, Villigen) et al.
Thanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams. A facility to produce helium beams at therapeutical energy can also accelerate protons, at energies permitting both standardised treatment and full body radiography, and heavier ions for treatment of shallow tumours and for research. [...]
2023
- Published in : JACoW IPAC 2023 (2023) THPM058
Fulltext: PDF;
In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.THPM058
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The next ion medical machine study at CERN: Towards a next generation cancer research and therapy facility with ion beams
/ Vretenar, Maurizio (CERN) ; Bencini, Vittorio (TERA Foundation (IT)) ; Khalvati, Mohammad Reza ; Lombardi, Alessandra (CERN) ; Tommasini, Davide (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Sapinski, Mariusz (SEEIIST Association (CH)) ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE))
Cancer therapy with ions has several advantages over X- ray and proton therapy, but its diffusion remains limited primarily because of the size and cost of the accelerator. To develop technologies that might improve performance and reduce accelerator cost with respect to present facilities, CERN has recently launched the Next Ion Medical Ma-chine Study (NIMMS), leveraging CERN expertise in accelerator fields to disseminate technologies developed for basic science. [...]
CERN-ACC-NOTE-2021-0018; NIMMS-Note-004.-
Geneva : CERN, 2021 - 6 p.
- Published in : JACoW IPAC2021 (2021) MOPAB413
Fulltext: document (3) - ; NIMMS_Note_004_Final - PDF;
In : 12th International Particle Accelerator Conference (IPAC 2021), Online, 24 - 28 May 2021, pp.MOPAB413
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Alvarez drift tube linac for medical applications in the framework of HITRIplus project
/ Mamaras, Aristeidis (Aristotle U., Thessaloniki ; CERN) ; Samponidis, D (Aristotle U., Thessaloniki ; CERN) ; Bellan, L (INFN-LNL, Legnaro, Italy) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Comunian, M (INFN-LNL, Leganro, Italy) ; Thonet, Pierre Alexandre (CERN) ; Vretenar, Maurizio (CERN)
A first beam dynamics and RF design of an Alvarez-type drift tube linac (DTL) has been defined in the framework of the EU project, HITRIplus. It is meant primarily as a carbon (12C4+) and helium (4He2+) ion injector of a compact synchrotron for patient treatment. [...]
CERN-ACC-NOTE-2023-0008; NIMMS-Note-014.-
Geneva : CERN, 2023 - 6 p.
- Published in : JACoW IPAC2023 (2023) TUPA176
Fulltext: NIMMS_Note_014_Final - PDF; TUPA176 - PDF;
In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.TUPA176
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Comparison of Accelerator Designs for an Ion Therapy and Research Facility
/ Benedetto, Elena (TERA Foundation (IT)) ; Amaldi, Ugo (TERA Foundation (IT)) ; Bencini, Vittorio (TERA Foundation (IT)) ; Dosanjh, Manjit ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE)) ; Kaprinis, Dimitris ; Khalvati, Mohammad Reza (Institute for Research in Fundamental Sciences (IR)) ; Lombardi, Alessandra (CERN) ; Sapinski, Mariusz (TERA Foundation (IT)) ; Vretenar, Maurizio (CERN) et al.
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CERN-ACC-NOTE-2020-0068 ; NIMMS-Note-001.
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2020. - 46 p.
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