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VHEE FLASH sparing effect measured at CLEAR, CERN with DNA damage of pBR322 plasmid as a biological endpoint
/ Wanstall, Hannah C (Manchester U. ; Daresbury) ; Korysko, Pierre (Oxford U. ; CERN) ; Farabolini, Wilfred (CERN) ; Corsini, Roberto (CERN) ; Bateman, Joseph J (Oxford U., Theor. Phys.) ; Rieker, Vilde (CERN ; Oslo U.) ; Hemming, Abigail (U. Manchester (main)) ; Henthorn, Nicholas T (U. Manchester (main) ; Manchester U.) ; Merchant, Michael J (Manchester U.) ; Santina, Elham (Manchester U.) et al.
Ultra-high dose rate (UHDR) irradiation has been shown to have a sparing effect on healthy tissue, an effect known as ‘FLASH’. This effect has been studied across several radiation modalities, including photons, protons and clinical energy electrons, however, very little data is available for the effect of FLASH with Very High Energy Electrons (VHEE). [...]
2024 - 13 p.
- Published in : Sci. Rep. 14 (2024) 14803
Fulltext: PDF;
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Influence of heterogeneous media on Very High Energy Electron (VHEE) dose penetration and a Monte Carlo-based comparison with existing radiotherapy modalities
/ Lagzda, Agnese (Manchester U. ; Cockcroft Inst. Accel. Sci. Tech.) ; Angal-Kalinin, Deepa (Cockcroft Inst. Accel. Sci. Tech. ; Daresbury) ; Jones, James (Cockcroft Inst. Accel. Sci. Tech. ; Daresbury) ; Aitkenhead, Adam (Unlisted, UK ; Manchester U.) ; Kirkby, Karen J (Unlisted, UK ; Manchester U.) ; MacKay, Ranald (Unlisted, UK ; Manchester U.) ; Van Herk, Marcel (Unlisted, UK ; Manchester U.) ; Farabolini, Wilfrid (CERN) ; Zeeshan, Sumaira (CERN) ; Jones, Roger M (Manchester U. ; Cockcroft Inst. Accel. Sci. Tech.)
• First experimental demonstration of the relative insensitivity of VHEE beams to inhomogeneities. • Topas/GEANT4 simulations on experiments conducted at CERN’s CLEAR facility are in good agreement. [...]
2020 - 12 p.
- Published in : Nucl. Instrum. Methods Phys. Res., B 482 (2020) 70-81
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HOM characterization for beam diagnostics at the european XFEL injector
/ Baboi, Nicoletta (DESY) ; Hellert, Thorsten (DESY and University of Hamburg) ; Shi, Liangliang (DESY and Manchester University) ; Wamsat, Thomas, DESY ; Jones, Roger M (Cockcroft Institute and Manchester University) ; Joshi, Nirav (Cockcroft Institute and Manchester University)
Higher Order Modes (HOM) excited by bunched electron beams in accelerating cavities carry information about the beam position and phase. This principle is used at the FLASH facility, at DESY, for beam position monitoring in 1.3 and 3.9 GHz cavities. [...]
CERN-ACC-2017-0046.-
Geneva : CERN, 2017
- Published in :
Fulltext: PDF;
In : International Beam Instrumentation Conference, Barcelona, Spain, 11 - 15 Sep 2016, pp.WEPG03
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Measurement of beam phase at FLASH using HOMs in accelerating cavities
/ Shi, Lianliang (Manchester University and Cockcroft Institute and DESY) ; Baboi, Nicoletta (DESY) ; Jones, Roger M (Manchester University and Cockcroft Institute) ; Joshi, Nirav (Manchester University and Cockcroft Institute)
The beam phase relative to the accelerating field is of vital importance for the quality of photon beams produced in modern Free Electron Lasers based on superconducting cavities. Normally, the phase is determined by detecting the transient field induced by the beam. [...]
CERN-ACC-2017-0044.-
Geneva : CERN, 2017
- Published in : 10.18429/JACoW-IPAC2016-MOPOR039
Fulltext: CERN-ACC-2017-0044 - PDF; Fulltext - PDF;
In : 7th International Particle Accelerator Conference, Busan, Korea, 8 - 13 May 2016, pp.MOPOR039
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Eigenmode compendium of the third harmonic module of the European X-ray Free Electron Laser
/ Flisgen, Thomas (Rostock U.) ; Heller, Johann (Rostock Universitaet) ; Galek, Tomasz, Rostock Universitaet ; Shi, Liangliang (Cockcroft institute, Manchester University and DESY) ; Joshi, Nirav (Manchester University) ; Baboi, Nicoletta (DESY) ; Jones, Roger M (Cockcroft Institute and Manchester University) ; van Rienen, Ursula (Rockstock Universitaet)
Chains of superconducting radio-frequency resonators are key components of modern particle accelerators such as the European XFEL, which is currently under construction in the north of Germany. In addition to the accelerating mode of the resonators, their beam excited higher order modes are of special interest, because they can harm the beam quality. [...]
CERN-ACC-2017-0041.-
Geneva : CERN, 2017
- Published in : Phys. Rev. Accel. Beams 20 (2017) 042002
Fulltext: PDF;
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Measurement of the dynamic response of the CERN DC spark system and preliminary estimates of the breakdown turn-on time
/ Shipman, Nicholas (Cockcroft Inst. Accel. Sci. Tech.) ; Jones, Roger M. (Cockcroft Inst. Accel. Sci. Tech.) ; Calatroni, Sergio (CERN) ; Wuensch, Walter (CERN)
The new High Repetition Rate (HRR) CERN DC Spark System has been used to investigate the current and voltage time structure of a breakdown. Simulations indicate that vacuum breakdowns develop on ns timescales or even less. [...]
IPAC-2012-THPPC027; arXiv:1206.0573; CLIC-Note-971.-
Geneva : CERN, 2012 - 3 p.
- Published in : Conf. Proc.: C1205201 (2012) , pp. THPPC027
Fulltext: CERN-ATS-2012-132 - PDF; arXiv:1206.0573 - PDF; CLIC_note_971 - PDF; External link: Full-text at JACoW Server
In : 3rd International Particle Accelerator Conference, New Orleans, LA, USA, 20 - 25 May 2012, pp.3338-3340
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Beam Dynamics Studies of the REX-ISOLDE Linac in Preparation for its Role as Injector for the HIE-ISOLDE SC Linac at CERN
/ Fraser, Matthew A. (U. Manchester (main)) ; Pasini, Matteo (Leuven U.) ; Jones, Roger M. (U. Manchester (main)) ; Voulot, Didier (CERN)
The superconducting (SC) High Intensity and Energy (HIE) ISOLDE linac will replace most of the existing accelerating infrastructure of the Radioactive ion beam EXperiment (REX) at CERN, however, the 101.28 MHz RFQ and 5 MV IH cavity will remain in the role of injector for the upgrade, boosting the beam up to an energy of 1.2 MeV/u. We present the results of a beam dynamics investigation of the injector focused most critically on matching the longitudinal beam parameters from the RFQ to the SC machine, which is complicated largely by the IH cavity employing a Combined Zero Degree (KONUS) beam dynamics design. [...]
arXiv:1010.2029.-
Geneva : CERN, 2011-04 - 3 p.
Fulltext: arXiv:1010.2029 - PDF; CERN-ATS-2010-206 - PDF; Published version from LINAC10: PDF; External link: Full-text at JACoW Server
In : 25th Linear Accelerator Conference, Tsukuba, Japan, 12 - 17 Sep 2010, pp.THP089
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Beam Dynamics Studies for the HIE-ISOLDE Linac at CERN
/ Fraser, Matthew A. (Manchester U. ; Cockcroft Inst. Accel. Sci. Tech.) ; Pasini, Matteo (Leuven U. ; CERN) ; Jones, Roger M. (Manchester U.) ; Lindroos, Mats (CERN)
The upgrade of the normal conducting (NC) Radioactive Ion Beam EXperiment (REX)-ISOLDE heavy ion accelerator at CERN, under the High Intensity and Energy (HIE)- ISOLDE framework, proposes the use of superconducting (SC) quarter-wave resonators (QWRs) to increase the energy capability of the facility from 3 MeV/u to beyond 10 MeV/u. A beam dynamics study of a lattice design comprising SC QWRs and SC solenoids has confirmed the design’s ability to accelerate ions, with a mass-to-charge ratio in the range 2.5 < A/q < 4.5, to the target energy with a minimal emittance increase. [...]
arXiv:0906.3484.-
Geneva : CERN, 2010-12 - 3 p.
- Published in : (2010) , pp. TH6PFP026
Fulltext: arXiv:0906.3484 - PDF; CERN-ATS-2009-094 - PDF; Published version from PAC09: PDF; External link: Full-text at JACoW Server
In : Particle Accelerator Conference 2009, Vancouver, Canada, 04 - 08 May 2009, pp.TH6PFP026
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Wakefield damping for the CLIC crab cavity
/ Ambattu, Praveen Kumar (Cockcroft Inst. Accel. Sci. Tech. ; Lancaster U.) ; Burt, Graeme (Cockcroft Inst. Accel. Sci. Tech. ; Lancaster U.) ; Dexter, Amos C. (Cockcroft Inst. Accel. Sci. Tech. ; Lancaster U.) ; Carter, Richard G. (Cockcroft Inst. Accel. Sci. Tech. ; Lancaster U.) ; Khan, Vasim (Cockcroft Inst. Accel. Sci. Tech. ; Manchester U.) ; Jones, Roger M. (Cockcroft Inst. Accel. Sci. Tech. ; Manchester U.) ; Dolgashev, Valery (SLAC)
A crab cavity is required in the CLIC to allow effective head-on collision of bunches at the IP. A high operating frequency is preferred as the deflection voltage required for a given rotation angle and the RF phase tolerance for a crab cavity are inversely proportional to the operating frequency. [...]
arXiv:0906.3593; SLAC-PUB-14814.-
2010-12 - 3 p.
- Published in : (2010) , pp. TU5PFP006
Preprint: PDF; External links: SLAC; JACOW
In : Particle Accelerator Conference 2009, Vancouver, Canada, 04 - 08 May 2009, pp.TU5PFP006
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