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普魯士藍 (醫用)：修订间差异

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'''普魯士藍'''（Prussian blue），又名'''六氰基铁酸钾'''（potassium ferric hexacyanoferrate），用于治疗[[铊中毒]]或[[铯|放射性铯中毒]]<ref name="WHO2008">{{Cite book |title=WHO Model Formulary 2008 |author-link=World Health Organization |publisher=World Health Organization |year=2009 |isbn=9789241547659 |page=65 |vauthors=((World Health Organization))}}</ref><ref name="Ric2015">{{Cite book|author=Hamilton|first=Richart|title=Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition|date=2015|publisher=Jones & Bartlett Learning|isbn=9781284057560|page=472}}</ref>。铊中毒時，除了[[洗胃]]、[[活性炭]]、{{tsl|en|Diuresis|利尿|强制利尿}}和[[血液透析]]外，也可用它來治療<ref name="AHFS2017">{{Cite web |title=Prussian Blue |url=https://www.drugs.com/monograph/prussian-blue.html |url-status=live |archive-url=https://web.archive.org/web/20170118044341/https://www.drugs.com/monograph/prussian-blue.html |archive-date=18 January 2017 |access-date=8 January 2017 |publisher=The American Society of Health-System Pharmacists}}</ref><ref name="Dart2004" />。可以口服或[[鼻胃管]]给药<ref name="Ric2015" /><ref name="Dart2004">{{Cite book|author=Dart|first=Richard C.|title=Medical Toxicology|date=2004|publisher=Lippincott Williams & Wilkins|isbn=9780781728454|page=248,279|url=https://books.google.ca/books?id=BfdighlyGiwC&pg=PA270|language=en|archiveurl=https://web.archive.org/web/20170116174329/https://books.google.ca/books?id=BfdighlyGiwC&pg=PA270|archivedate=2017-01-16}}</ref>。[[普鲁士蓝]]也用于[[葡萄糖-6-磷酸脫氫酶缺乏症]]的尿液检测<ref name="Med2017Diag">{{Cite web|url=http://medlibes.com/entry/glucose-6-phosphate-dehyrogenase-deficiency|title=Glucose-6-phosphate dehyrogenase deficiency — Medlibes: Online Medical Library|website=medlibes.com|access-date=2017-05-03|url-status=live|archive-url=https://web.archive.org/web/20160915060308/http://medlibes.com/entry/glucose-6-phosphate-dehyrogenase-deficiency|archive-date=2016-09-15}}</ref>。


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副作用可能包括[[便秘]]、[[低鉀血症]]和大便发黑<ref name="WHO2008" /><ref name="AHFS2017" />。长期使用后，汗液可能会变成蓝色<ref name="AHFS2017" />。作用機轉是与铊和铯结合後，減少人體由[[消化道]]吸收它們<ref name="AHFS2017" />。
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'''普魯士藍'''（Prussian blue），又名'''六氰基铁酸钾'''（potassium ferric hexacyanoferrate），用于治疗[[铊中毒]]或[[铯|放射性铯中毒]]<ref name="WHO2008">{{Cite book|title=WHO Model Formulary 2008|year=2009|isbn=9789241547659|vauthors=((World Health Organization))|author-link=World Health Organization|publisher=World Health Organization|page=65}}<cite class="citation book cs1" data-ve-ignore="true" id="CITEREFWorld_Health_Organization2009">[[世界卫生组织|World Health Organization]] (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). ''WHO Model Formulary 2008''. World Health Organization. p.&nbsp;65. [[Hdl (identifier)|hdl]]:<span class="id-lock-free" title="Freely accessible">[https://hdl.handle.net/10665%2F44053 10665/44053]</span>. [[国际标准书号|ISBN]]&nbsp;[[Special:BookSources/9789241547659|<bdi>9789241547659</bdi>]].</cite></ref> <ref name="Ric2015">{{Cite book|author=Hamilton|first=Richart|title=Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition|date=2015|publisher=Jones & Bartlett Learning|isbn=9781284057560|page=472}}</ref>。铊中毒時，除了[[洗胃]]、[[活性炭]]、{{tsl|en|Diuresis|利尿|强制利尿}}和[[血液透析]]外，也可用它來治療<ref name="AHFS2017">{{Cite web|title=Prussian Blue|url=https://www.drugs.com/monograph/prussian-blue.html|publisher=The American Society of Health-System Pharmacists|access-date=8 January 2017|url-status=live|archive-url=https://web.archive.org/web/20170118044341/https://www.drugs.com/monograph/prussian-blue.html|archive-date=18 January 2017}}<cite class="citation web cs1" data-ve-ignore="true">[https://www.drugs.com/monograph/prussian-blue.html "Prussian Blue"]. The American Society of Health-System Pharmacists. [https://web.archive.org/web/20170118044341/https://www.drugs.com/monograph/prussian-blue.html Archived] from the original on 18 January 2017<span class="reference-accessdate">. Retrieved <span class="nowrap">8 January</span> 2017</span>.</cite></ref> <ref name="Dart2004" />。可以口服或[[鼻胃管]]给药<ref name="Ric2015" /> <ref name="Dart2004">{{Cite book|author=Dart|first=Richard C.|title=Medical Toxicology|date=2004|publisher=Lippincott Williams & Wilkins|isbn=9780781728454|page=248,279|url=https://books.google.ca/books?id=BfdighlyGiwC&pg=PA270|language=en|archiveurl=https://web.archive.org/web/20170116174329/https://books.google.ca/books?id=BfdighlyGiwC&pg=PA270|archivedate=2017-01-16}}</ref>。[[普鲁士蓝]]也用于[[葡萄糖-6-磷酸脫氫酶缺乏症]]的尿液检测<ref name="Med2017Diag">{{Cite web|url=http://medlibes.com/entry/glucose-6-phosphate-dehyrogenase-deficiency|title=Glucose-6-phosphate dehyrogenase deficiency — Medlibes: Online Medical Library|website=medlibes.com|access-date=2017-05-03|url-status=live|archive-url=https://web.archive.org/web/20160915060308/http://medlibes.com/entry/glucose-6-phosphate-dehyrogenase-deficiency|archive-date=2016-09-15}}</ref>。


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普魯士藍在 1706 年左右发現<ref>{{Cite book|author=Hall|first=Alan H.|author2=Isom|first2=Gary E.|author3=Rockwood|first3=Gary A.|title=Toxicology of Cyanides and Cyanogens: Experimental, Applied and Clinical Aspects|date=2015|publisher=John Wiley & Sons|isbn=9781118628942|page=43|url=https://books.google.ca/books?id=rF2-CgAAQBAJ&pg=PA43|language=en|archiveurl=https://web.archive.org/web/20170116174254/https://books.google.ca/books?id=rF2-CgAAQBAJ&pg=PA43|archivedate=2017-01-16}}</ref>。已列入[[世界卫生组织基本药物标准清单]]<ref name="WHO21st">{{Cite book|vauthors=((World Health Organization))|title=World Health Organization model list of essential medicines: 21st list 2019|year=2019|author-link=World Health Organization|publisher=World Health Organization|location=Geneva|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO}}</ref>。{{As of|2016}} ，仅在德国、美国和日本取得医疗使用許可<ref>{{Cite book|author=Goyer|first=Robert A.|title=Metal Toxicology: Approaches and Methods|date=2016|publisher=Elsevier|isbn=9781483288567|page=93|url=https://books.google.ca/books?id=DiElBQAAQBAJ&pg=PA93|language=en|accessdate=2017-01-15|archivedate=2017-09-18|archiveurl=https://web.archive.org/web/20170918184711/https://books.google.ca/books?id=DiElBQAAQBAJ&pg=PA93}}</ref><ref>{{Cite book|author=Dobbs|first=Michael R.|title=Clinical Neurotoxicology: Syndromes, Substances, Environments|date=2009|publisher=Elsevier Health Sciences|isbn=0323052606|page=280|url=https://books.google.ca/books?id=Pmcy24y2HyMC&pg=PA280|language=en|accessdate=2017-01-15|archivedate=2017-01-16|archiveurl=https://web.archive.org/web/20170116173304/https://books.google.ca/books?id=Pmcy24y2HyMC&pg=PA280}}</ref><ref>{{Cite journal|title=Radioaktivität: Berliner Blau als Arzneimittel|journal=Dtsch Arztebl|date=1 July 2011|url=https://www.aerzteblatt.de/archiv/95515/Radioaktivitaet-Berliner-Blau-als-Arzneimittel|language=de|access-date=10 December 2018|archive-date=14 December 2018|archive-url=https://web.archive.org/web/20181214070558/https://www.aerzteblatt.de/archiv/95515/Radioaktivitaet-Berliner-Blau-als-Arzneimittel|url-status=live}}</ref>。在世界上许多地区，包括[[已開發國家]]，医療用普鲁士蓝的取得常有困难<ref>{{Cite news|author=Archiver|first=Truthout|title=Fukushima's Cesium Spew - Deadly Catch-22s in Japan Disaster Relief|url=http://www.truth-out.org/news/item/1846:fukushimas-cesium-spew--deadly-catch22s-in-japan-disaster-relief|accessdate=15 January 2017|work=Truthout|date=27 June 2011|archiveurl=https://web.archive.org/web/20170116172041/http://www.truth-out.org/news/item/1846%3Afukushimas-cesium-spew--deadly-catch22s-in-japan-disaster-relief|archivedate=16 January 2017}}</ref>。
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副作用可能包括[[便秘]]、[[低鉀血症]]和大便发黑<ref name="WHO2008" /> <ref name="AHFS2017" />。长期使用后，汗液可能会变成蓝色<ref name="AHFS2017" />。作用機轉是与铊和铯结合後，減少人體由[[消化道]]吸收它們<ref name="AHFS2017" />。

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普魯士藍在 1706 年左右发現<ref>{{Cite book|author=Hall|first=Alan H.|author2=Isom|first2=Gary E.|author3=Rockwood|first3=Gary A.|title=Toxicology of Cyanides and Cyanogens: Experimental, Applied and Clinical Aspects|date=2015|publisher=John Wiley & Sons|isbn=9781118628942|page=43|url=https://books.google.ca/books?id=rF2-CgAAQBAJ&pg=PA43|language=en|archiveurl=https://web.archive.org/web/20170116174254/https://books.google.ca/books?id=rF2-CgAAQBAJ&pg=PA43|archivedate=2017-01-16}}</ref>。已列入[[世界卫生组织基本药物标准清单]]<ref name="WHO21st">{{Cite book|vauthors=((World Health Organization))|title=World Health Organization model list of essential medicines: 21st list 2019|year=2019|author-link=World Health Organization|publisher=World Health Organization|location=Geneva|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO}}</ref>。{{As of|2016}} ，仅在德国、美国和日本取得医疗使用許可<ref>{{Cite book|author=Goyer|first=Robert A.|title=Metal Toxicology: Approaches and Methods|date=2016|publisher=Elsevier|isbn=9781483288567|page=93|url=https://books.google.ca/books?id=DiElBQAAQBAJ&pg=PA93|language=en|accessdate=2017-01-15|archivedate=2017-09-18|archiveurl=https://web.archive.org/web/20170918184711/https://books.google.ca/books?id=DiElBQAAQBAJ&pg=PA93}}</ref> <ref>{{Cite book|author=Dobbs|first=Michael R.|title=Clinical Neurotoxicology: Syndromes, Substances, Environments|date=2009|publisher=Elsevier Health Sciences|isbn=0323052606|page=280|url=https://books.google.ca/books?id=Pmcy24y2HyMC&pg=PA280|language=en|accessdate=2017-01-15|archivedate=2017-01-16|archiveurl=https://web.archive.org/web/20170116173304/https://books.google.ca/books?id=Pmcy24y2HyMC&pg=PA280}}</ref> <ref>{{Cite journal|title=Radioaktivität: Berliner Blau als Arzneimittel|journal=Dtsch Arztebl|date=1 July 2011|url=https://www.aerzteblatt.de/archiv/95515/Radioaktivitaet-Berliner-Blau-als-Arzneimittel|language=de|access-date=10 December 2018|archive-date=14 December 2018|archive-url=https://web.archive.org/web/20181214070558/https://www.aerzteblatt.de/archiv/95515/Radioaktivitaet-Berliner-Blau-als-Arzneimittel|url-status=live}}</ref>。在世界上许多地区，包括[[已開發國家]]，医療用普鲁士蓝的取得常有困难<ref>{{Cite news|author=Archiver|first=Truthout|title=Fukushima's Cesium Spew - Deadly Catch-22s in Japan Disaster Relief|url=http://www.truth-out.org/news/item/1846:fukushimas-cesium-spew--deadly-catch22s-in-japan-disaster-relief|accessdate=15 January 2017|work=Truthout|date=27 June 2011|archiveurl=https://web.archive.org/web/20170116172041/http://www.truth-out.org/news/item/1846%3Afukushimas-cesium-spew--deadly-catch22s-in-japan-disaster-relief|archivedate=16 January 2017}}</ref>。


== 参考文獻 ==
== 参考文獻 ==

2024年12月25日 (三) 12:10的最新版本

参见：普魯士藍
普魯士藍
普魯士藍
臨床資料
商品名（英语：Drug nomenclature）Radiogardase, others
AHFS/Drugs.comMonograph
给药途径口服
化学信息
摩尔质量859.24

普魯士藍（Prussian blue），又名六氰基铁酸钾（potassium ferric hexacyanoferrate），用于治疗铊中毒或放射性铯中毒[1][4]。铊中毒時，除了洗胃、活性炭、强制利尿和血液透析外，也可用它來治療[2][5]。可以口服或鼻胃管给药[4][5]。普鲁士蓝也用于葡萄糖-6-磷酸脫氫酶缺乏症的尿液检测[6]。

副作用可能包括便秘、低鉀血症和大便发黑[1][2]。长期使用后，汗液可能会变成蓝色[2]。作用機轉是与铊和铯结合後，減少人體由消化道吸收它們[2]。

普魯士藍在 1706 年左右发現[7]。已列入世界卫生组织基本药物标准清单[8]。截至2016年 (2016-Missing required parameter 1=month!) ，仅在德国、美国和日本取得医疗使用許可[9][10][11]。在世界上许多地区，包括已開發國家，医療用普鲁士蓝的取得常有困难[12]。

参考文獻

[编辑]
  1. ^ 1.0 1.1 1.2 1.3 World Health Organization. WHO Model Formulary 2008. World Health Organization. 2009: 65. ISBN 9789241547659. 
  2. ^ 2.0 2.1 2.2 2.3 2.4 Prussian Blue. The American Society of Health-System Pharmacists. [8 January 2017]. （原始内容存档于18 January 2017）. 
  3. ^ WHOCC - ATC/DDD Index. www.whocc.no. [13 September 2020]. （原始内容存档于21 October 2020）. 
  4. ^ 4.0 4.1 Hamilton, Richart. Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. 2015: 472. ISBN 9781284057560. 
  5. ^ 5.0 5.1 Dart, Richard C. Medical Toxicology. Lippincott Williams & Wilkins. 2004: 248,279. ISBN 9780781728454. （原始内容存档于2017-01-16） （英语）. 
  6. ^ Glucose-6-phosphate dehyrogenase deficiency — Medlibes: Online Medical Library. medlibes.com. [2017-05-03]. （原始内容存档于2016-09-15）. 
  7. ^ Hall, Alan H.; Isom, Gary E.; Rockwood, Gary A. Toxicology of Cyanides and Cyanogens: Experimental, Applied and Clinical Aspects. John Wiley & Sons. 2015: 43. ISBN 9781118628942. （原始内容存档于2017-01-16） （英语）. 
  8. ^ World Health Organization. World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. 
  9. ^ Goyer, Robert A. Metal Toxicology: Approaches and Methods. Elsevier. 2016: 93 [2017-01-15]. ISBN 9781483288567. （原始内容存档于2017-09-18） （英语）. 
  10. ^ Dobbs, Michael R. Clinical Neurotoxicology: Syndromes, Substances, Environments. Elsevier Health Sciences. 2009: 280 [2017-01-15]. ISBN 0323052606. （原始内容存档于2017-01-16） （英语）. 
  11. ^ Radioaktivität: Berliner Blau als Arzneimittel. Dtsch Arztebl. 1 July 2011 [10 December 2018]. （原始内容存档于14 December 2018） （德语）. 
  12. ^ Archiver, Truthout. Fukushima's Cesium Spew - Deadly Catch-22s in Japan Disaster Relief. Truthout. 27 June 2011 [15 January 2017]. （原始内容存档于16 January 2017）. 
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