Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats (Q89379804)

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4 April 2020

title

Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats (English)

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4 April 2020

1

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4 April 2020

author name string

Ashley J McFalls

2

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4 April 2020

Niran Hadad

3

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4 April 2020

Laura Blanco-Berdugo

4

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4 April 2020

Dustin R Masser

5

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4 April 2020

Elizabeth M Colechio

6

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4 April 2020

Alissa A Coffey

7

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4 April 2020

Georgina V Bixler

8

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4 April 2020

David R Stanford

9

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4 April 2020

Kent E Vrana

10

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4 April 2020

Patricia S Grigson

11

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4 April 2020

Willard M Freeman

12

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publication date

28 June 2018

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4 April 2020

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4 April 2020

volume

139

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page(s)

26-40

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Effects of environment on morphology of rat cerebral cortex and hippocampus

4 April 2020

cites work

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https://pubmed.ncbi.nlm.nih.gov/29964093

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DNA methylation and gene expression

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12 December 2020

Increases in cortical depth and glia numbers in rats subjected to enriched environment

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Effects of environmental enrichment and impoverishment on rat cerebral cortex

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12 December 2020

The effects of environmental complexity on the histology of the rat hippocampus

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12 December 2020

Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.

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12 December 2020

Transition from moderate to excessive drug intake: change in hedonic set point.

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12 December 2020

Choice between money and intranasal heroin in morphine-maintained humans.

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12 December 2020

Orchestrated response: a symphony of transcription factors for gene control

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12 December 2020

Neural consequences of environmental enrichment

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12 December 2020

Cocaine-responsive gene expression changes in rat hippocampus.

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12 December 2020

Cocaine-induced suppression of saccharin intake: a model of drug-induced devaluation of natural rewards

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12 December 2020

Brief access to sweets protect against relapse to cocaine-seeking.

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12 December 2020

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction

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12 December 2020

Identification of a BMP inhibitor-responsive promoter module required for expression of the early neural gene zic1.

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12 December 2020

Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation.

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12 December 2020

Predicting long-term stable recovery from heroin addiction: findings from a 33-year follow-up study

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12 December 2020

Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring

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12 December 2020

Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior

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12 December 2020

Heroin self-administration: I. Incubation of goal-directed behavior in rats.

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12 December 2020

Genetic susceptibility to heroin addiction: a candidate gene association study

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12 December 2020

Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Selective breeding for differential saccharin intake as an animal model of drug abuse.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Reversal of cocaine addiction by environmental enrichment.

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12 December 2020

Environmental enrichment decreases the rewarding but not the activating effects of heroin.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment attenuates cue-induced reinstatement of sucrose seeking in rats

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12 December 2020

Aerobic exercise for alcohol recovery: rationale, program description, and preliminary findings

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12 December 2020

Neurobehavioral effects of environmental enrichment and drug abuse vulnerability

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12 December 2020

Gene expression changes following extinction testing in a heroin behavioral incubation model

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12 December 2020

Environmental enrichment reduces cocaine seeking and reinstatement induced by cues and stress but not by cocaine

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12 December 2020

Reward Comparison: The Achilles' heel and hope for addiction.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Prevention and treatment of drug addiction by environmental enrichment.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Initiation into prescription opioid misuse amongst young injection drug users

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment protects against the acquisition of cocaine self-administration in adult male rats, but does not eliminate avoidance of a drug-associated saccharin cue.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Loss of environmental enrichment increases vulnerability to cocaine addiction

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12 December 2020

Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Functions of DNA methylation: islands, start sites, gene bodies and beyond

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Epigenetics of drug abuse: predisposition or response

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Functional analysis of transcription factor binding sites in human promoters

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Extended heroin access increases heroin choices over a potent nondrug alternative.

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12 December 2020

Effect of chronic heroin and cocaine administration on global DNA methylation in brain and liver.

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12 December 2020

A novel model of chronic sleep restriction reveals an increase in the perceived incentive reward value of cocaine in high drug-taking rats.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Epigenetic mechanisms of drug addiction

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12 December 2020

Global epigenomic reconfiguration during mammalian brain development

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12 December 2020

A choice-based screening method for compulsive drug users in rats.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum.

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12 December 2020

DNA methylation regulates associative reward learning

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12 December 2020

Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

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12 December 2020

Cellular basis of memory for addiction

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12 December 2020

Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Drug versus sweet reward: greater attraction to and preference for sweet versus drug cues

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

The changing face of heroin use in the United States: a retrospective analysis of the past 50 years

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Epigenetically modified nucleotides in chronic heroin and cocaine treated mice

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12 December 2020

Function and information content of DNA methylation

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Targeted DNA methylation analysis by next-generation sequencing

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental Enrichment Reduces Anxiety by Differentially Activating Serotonergic and Neuropeptide Y (NPY)-Ergic System in Indian Field Mouse (Mus booduga): An Animal Model of Post-Traumatic Stress Disorder

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Epigenetic changes in the developing brain: Effects on behavior

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12 December 2020

Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Non-CG Methylation in the Human Genome.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Greater avoidance of a heroin-paired taste cue is associated with greater escalation of heroin self-administration in rats

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Turning over DNA methylation in the mind

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Methadone induces hypermethylation of human DNA.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment induces early heroin abstinence in an animal conflict model

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Reversal of the sleep-wake cycle by heroin self-administration in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment as a potential intervention for heroin seeking

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Neurobiology of addiction: a neurocircuitry analysis

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Long-lasting effects of adolescent oxycodone exposure on reward-related behavior and gene expression in mice.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Environmental enrichment reduces chronic psychosocial stress-induced anxiety and ethanol-related behaviors in mice

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Opioid addiction: Who are your real friends?

1 reference

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12 December 2020

DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age.

1 reference

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12 December 2020

The societal cost of heroin use disorder in the United States.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

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12 December 2020

Comparison of chronic physical and emotional social defeat stress effects on mesocorticolimbic circuit activation and voluntary consumption of morphine

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Once is too much: Early development of the opponent process in taste reactivity behavior is associated with later escalation of cocaine self-administration in rats.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

Analysis of DNA modifications in aging research.

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https://pubmed.ncbi.nlm.nih.gov/29964093

12 December 2020

10.1016/J.NEUROPHARM.2018.06.037

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29964093%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

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4 April 2020

PubMed publication ID

29964093

1 reference