Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis (Q81004145)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

review article

1 reference

title

Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Yihai Cao

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

publication date

1 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

735-743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

The case for early detection

5 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Clinical and pathologic features of invasive micropapillary carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Breast cancer screening: Preliminary report of 207 biopsies performed in 4,128 volunteer screenees

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Molecular portraits of human breast tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Patterns of metastatic breast carcinoma: influence of tumour histological grade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Gene expression profiling predicts clinical outcome of breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Blood and lymphatic vessel invasion as prognostic factors for patients with primary resected nonsmall cell carcinoma of the lung with intrapulmonary metastases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Detection of disseminated tumor cells in peripheral blood of patients with breast cancer: correlation to nodal status and occurrence of metastases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphogenous and hematogenous metastasis of Lewis lung carcinoma in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Focus on lymphangiogenesis in tumor metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphangiogenesis and cancer metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphatic endothelium: morphological, molecular and functional properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Studies on the permeability of lymphatic capillaries

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Peritumor lymphatics induced by vascular endothelial growth factor-C exhibit abnormal function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphatic metastasis in the absence of functional intratumor lymphatics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Differential permeability of lymphatic and blood vessels in determining the route of metastasis as demonstrated by indirect lymphography

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphangiogenesis and Cancer: Fig. 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphangiogenesis new mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Dose-dependent response of FGF-2 for lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Dual role of Ang2 in postnatal angiogenesis and lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiogenesis in cancer, vascular, rheumatoid and other disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Transplacental carcinogenesis by stilbestrol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Tumour suppressor p53 inhibits human fibroblast growth factor 2 expression by a post-transcriptional mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Characterization of a new human glioblastoma cell line that expresses mutant p53 and lacks activation of the PDGF pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

pRb, Myc and p53 are critically involved in SV40 large T antigen repression of PDGF beta-receptor transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

HIF-1alpha is essential for myeloid cell-mediated inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Von Hippel-Lindau disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphangiogenic growth factors, receptors and therapies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

High interstitial fluid pressure - an obstacle in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Direct role of PDGF-BB in lymphangiogenesis and lymphatic metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiogenic and lymphangiogenic microvessel density in breast carcinoma: correlation with clinicopathologic parameters and VEGF-family gene expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Inhibition of Hemangiogenesis and LymphangiogenesisafterNormal-Risk Corneal Transplantation by Neutralizing VEGF Promotes Graft Survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic Metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiogenesis in cancer and other diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Comparative Evaluation of FGF-2–, VEGF-A–, and VEGF-C–Induced Angiogenesis, Lymphangiogenesis, Vascular Fenestrations, and Permeability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

The PDGF family: four gene products form five dimeric isoforms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Platelet-derived growth factor. Structure, function and implications in normal and malignant cell growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Insight into the physiological functions of PDGF through genetic studies in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Roles of PDGF in animal development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular endothelial growth factor and platelet-derived growth factor are potential angiogenic and metastatic factors in human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

The role of fibroblast growth factors in vascular development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Human acidic fibroblast growth factor overexpressed in insect cells is not secreted into the medium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Novel forms of acidic fibroblast growth factor-1 are constitutively exported by beta tumor cell lines independent from conventional secretion and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Vascular-specific growth factors and blood vessel formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

A model for gene therapy of human hereditary lymphedema

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Inflammatory triggers of lymphangiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Re: Influence of the new AJCC breast cancer staging system on sentinel lymph node positivity and false-negative rates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Inhibition of lymphangiogenesis-related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproteinase inhibitor MMI270

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC1693

31 March 2020

Identifiers

DOI

10.1038/NRC1693

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16079909%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 January 2020

1014855939

0 references

1 reference