The physiological role of cytotoxic CD4(+) T-cells: the holy grail? (Q80576888)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

The physiological role of cytotoxic CD4(+) T-cells: the holy grail? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Appay V

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

1 October 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Experimental Immunology

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

10-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection

1 January 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

HIV-1-specific memory CD4+ T cells are phenotypically less mature than cytomegalovirus-specific memory CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Cytotoxic CD4+ T cells in patients with B cell chronic lymphocytic leukemia kill via a perforin-mediated pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

T cell killing does not require the formation of a stable mature immunological synapse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Lessons from the study of T-cell differentiation in persistent human virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Properties of CD4(+) T cells in human cytomegalovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

CD4 T cells producing IFN-gamma in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Acquisition of specific cytotoxic activity by human T4+ T lymphocytes in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Expression of specific cytolytic activity by H-2I region-restricted, influenza virus-specific T lymphocyte clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Recognition of MHC class I allodeterminants regulates the generation of MHC class II-specific CTL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Individual variation in the frequency of HLA class II-specific cytotoxic T lymphocyte precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

A CD4+ cytotoxic T-lymphocyte clone to a conserved epitope on human immunodeficiency virus type 1 p24: cytotoxic activity and secretion of interleukin-2 and interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Specific lysis of targets expressing varicella-zoster virus gpI or gpIV by CD4+ human T-cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Poliovirus-specific CD4+ Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Functional subsets of CD4 T cells in rheumatoid synovitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Characterization of CD4(+) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Granule exocytosis, and not the fas/fas ligand system, is the main pathway of cytotoxicity mediated by alloantigen-specific CD4(+) as well as CD8(+) cytotoxic T lymphocytes in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Cutaneous T cell lymphoma reactive CD4+ cytotoxic T lymphocyte clones display a Th1 cytokine profile and use a fas-independent pathway for specific tumor cell lysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28- T cells in ankylosing spondylitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold

1 reference

https://pubmed.ncbi.nlm.nih.gov/15373899

12 December 2020

10.1111/J.1365-2249.2004.02605.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15373899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PMC publication ID

1809194

0 references

1 reference