Off the beaten pathway: the complex cross talk between Notch and NF-kappaB (Q80146628)

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29 December 2019

title

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB (English)

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29 December 2019

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4

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29 December 2019

author name string

Clodia Osipo

series ordinal

1

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29 December 2019

Todd E Golde

series ordinal

2

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29 December 2019

Barbara A Osborne

series ordinal

3

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29 December 2019

publication date

3 December 2007

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29 December 2019

published in

Laboratory Investigation

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29 December 2019

volume

88

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29 December 2019

issue

1

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29 December 2019

page(s)

11-17

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29 December 2019

1 reference

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Notch signaling in cancer.

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Targeting transcription factors in acute leukemia in children

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Regulation of lymphocyte development by Notch signaling

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Notch signaling in development and cancer.

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7 January 2021

The multifaceted role of Notch in cancer

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7 January 2021

Notch signaling: control of cell communication and cell fate

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7 January 2021

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

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7 January 2021

Structural basis for autoinhibition of Notch

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7 January 2021

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

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7 January 2021

Gamma-secretase: proteasome of the membrane?

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Notch signaling: cell fate control and signal integration in development

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7 January 2021

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

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7 January 2021

Control of cell proliferation in the Drosophila eye by Notch signaling.

1 reference

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7 January 2021

Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells

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7 January 2021

Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis

1 reference

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7 January 2021

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

1 reference

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7 January 2021

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation

1 reference

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7 January 2021

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

1 reference

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7 January 2021

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

1 reference

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7 January 2021

p53 and NF-kappaB crosstalk: IKKalpha tips the balance

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7 January 2021

NF-kappa B signaling and carcinogenesis

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7 January 2021

Nuclear factor-kappaB in development, prevention, and therapy of cancer

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7 January 2021

NF-kappaB activation in development and progression of cancer

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7 January 2021

NF-kappa B as a target for cancer therapy

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7 January 2021

NF-kappa B as a therapeutic target in neurodegenerative diseases

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7 January 2021

NF-kappa B as a therapeutic target in autoimmune disease.

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7 January 2021

Regulation of NF-kappaB function.

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7 January 2021

Integrating cell-signalling pathways with NF-kappaB and IKK function

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7 January 2021

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

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7 January 2021

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

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7 January 2021

Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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7 January 2021

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

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7 January 2021

SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival

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7 January 2021

Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation

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Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

1 reference

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7 January 2021

IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

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IKKalpha stabilizes cytosolic beta-catenin by inhibiting both canonical and non-canonical degradation pathways

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IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation

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Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

1 reference

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IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

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7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

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Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin

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7 January 2021

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

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7 January 2021

IkappaB kinase is an essential component of the Tpl2 signaling pathway

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7 January 2021

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

1 reference

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Basal Expression of IκBα Is Controlled by the Mammalian Transcriptional Repressor RBP-J (CBF1) and Its Activator Notch1

1 reference

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7 January 2021

Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors

1 reference

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7 January 2021

Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes

1 reference

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7 January 2021

T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells

1 reference

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7 January 2021

Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain

1 reference

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7 January 2021

TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells

1 reference

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Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways

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Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

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7 January 2021

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

1 reference

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7 January 2021

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

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Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

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Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer.

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Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression

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Involvement of Notch signaling in hippocampal synaptic plasticity

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Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

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Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells

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Coexpression of Notch1 and NF-kappaB signaling pathway components in human cervical cancer progression

1 reference

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7 January 2021

10.1038/LABINVEST.3700700

Identifiers

DOI

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Dimensions Publication ID

29 December 2019

1000124458

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