Why does the myocardium fail? Insights from basic science (Q77296406)

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4 December 2019

review article

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title

Why does the myocardium fail? Insights from basic science (English)

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4 December 2019

author name string

M R Bristow

series ordinal

1

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4 December 2019

language of work or name

English

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publication date

1 August 1998

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4 December 2019

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4 December 2019

volume

352 Suppl 1

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4 December 2019

page(s)

SI8-14

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Survival after the onset of congestive heart failure in Framingham Heart Study subjects

4 December 2019

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A Point Mutation in the 5' Splice Site of the Dystrophin Gene First Intron Responsible for X-Linked Dilated Cardiomyopathy

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Localization of a gene responsible for familial dilated cardiomyopathy to chromosome 1q32.

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Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction

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Improvement in cardiac myocyte function by biological effects of medical therapy: a new concept in the treatment of heart failure

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The failing human heart is unable to use the Frank-Starling mechanism

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Existence of the Frank-Starling mechanism in the failing human heart. Investigations on the organ, tissue, and sarcomere levels

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Altered myocardial force-frequency relation in human heart failure

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Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition

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7 January 2021

Reduced Contraction and Altered Frequency Response of Isolated Ventricular Myocytes From Patients With Heart Failure

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Mechanism of action of beta-blocking agents in heart failure

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7 January 2021

Creatine kinase system in failing and nonfailing human myocardium

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7 January 2021

Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium

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7 January 2021

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

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7 January 2021

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

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7 January 2021

Differences in beta-adrenergic neuroeffector mechanisms in ischemic versus idiopathic dilated cardiomyopathy

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7 January 2021

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

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7 January 2021

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

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7 January 2021

Increase in myocardial Gi-proteins in heart failure

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7 January 2021

Radioimmunochemical quantification of Gi alpha in right and left ventricles from patients with ischaemic and dilated cardiomyopathy and predominant left ventricular failure

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7 January 2021

Beta-adrenergic neuroeffector abnormalities in the failing human heart are produced by local rather than systemic mechanisms

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7 January 2021

Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response

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7 January 2021

Intracoronary infusion of dobutamine to patients with and without severe congestive heart failure. Dose-response relationships, correlation with circulating catecholamines, and effect of phosphodiesterase inhibition

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7 January 2021

Role of beta-adrenergic receptor downregulation in the peak exercise response in patients with heart failure due to idiopathic dilated cardiomyopathy

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7 January 2021

Parasympathetic withdrawal is an integral component of autonomic imbalance in congestive heart failure: demonstration in human subjects and verification in a paced canine model of ventricular failure

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7 January 2021

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

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7 January 2021

Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation

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7 January 2021

Isolated myocyte contractile function is normal in postinfarct remodeled rat heart with systolic dysfunction

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7 January 2021

Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy

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Bioenergetic Consequences of Left Ventricular Remodeling

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7 January 2021

Coupling between myosin ATPase cycle and creatinine kinase cycle facilitates cardiac actomyosin sliding in vitro. A clue to mechanical dysfunction during myocardial ischemia

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7 January 2021

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7 January 2021

Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy

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7 January 2021

Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure

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7 January 2021

Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling

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7 January 2021

Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha

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7 January 2021

Control of cardiac gene expression by mechanical stress

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7 January 2021

Apoptosis in pressure overload-induced heart hypertrophy in the rat.

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7 January 2021

Human cardiac myosin heavy chain genes and their linkage in the genome

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7 January 2021

Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium

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7 January 2021

Recent Advances in the Molecular Genetics of Hypertrophic Cardiomyopathy

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7 January 2021

ATPase activity of myosin correlated with speed of muscle shortening

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7 January 2021

Regulation of human heart contractility by essential myosin light chain isoforms

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7 January 2021

Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle

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7 January 2021

Myosin heavy chain gene expression in human heart failure

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7 January 2021

Cross-bridge dynamics in human ventricular myocardium. Regulation of contractility in the failing heart

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7 January 2021

Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency

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7 January 2021

Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart

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7 January 2021

Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts

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7 January 2021

Beta-adrenergic function in heart muscle disease and heart failure

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7 January 2021

Decreased Gs alpha mRNA levels accompany the fall in Gs and adenylyl cyclase activities in compensated left ventricular hypertrophy. In heart failure, only the impairment in adenylyl cyclase activation progresses

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7 January 2021

Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy

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Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart

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Effects of metoprolol on myocardial beta-adrenoceptors and Gi alpha-proteins in patients with congestive heart failure

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7 January 2021

Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice

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7 January 2021

Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure

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7 January 2021

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

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7 January 2021

Ca2+ uptake by cardiac sarcoplasmic reticulum from patients with idiopathic dilated cardiomyopathy

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7 January 2021

Calcium antagonist binding sites in failing and nonfailing human ventricular myocardium

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7 January 2021

Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated Cardiomyopathy

1 reference

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7 January 2021

Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium

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7 January 2021

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

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7 January 2021

Left ventricular diastolic dysfunction as a cause of congestive heart failure. Mechanisms and management

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7 January 2021

10.1016/S0140-6736(98)90311-7

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DOI

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4 December 2019

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