Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis (Q73073993)

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1 November 2019

title

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis (English)

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1 November 2019

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7

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1 November 2019

Sebastian Wesselborg

13

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1 November 2019

author name string

Engels IH

1

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1 November 2019

Stepczynska A

2

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1 November 2019

Stroh C

3

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1 November 2019

Lauber K

4

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1 November 2019

Berg C

5

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1 November 2019

Schwenzer R

6

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1 November 2019

Jänicke RU

8

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1 November 2019

Porter AG

9

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1 November 2019

Belka C

10

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1 November 2019

Gregor M

11

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1 November 2019

Schulze-Osthoff K

12

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1 November 2019

language of work or name

English

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publication date

1 September 2000

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1 November 2019

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1 November 2019

volume

19

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1 November 2019

issue

40

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1 November 2019

page(s)

4563-4573

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The Bcl-2 protein family: arbiters of cell survival

1 November 2019

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The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.

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Caspases: the executioners of apoptosis

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Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1

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Oncogene-dependent apoptosis is mediated by caspase-9.

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Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

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E1B 19,000-molecular-weight protein interacts with and inhibits CED-4-dependent, FLICE-mediated apoptosis

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7 January 2021

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

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7 January 2021

I-FLICE, a Novel Inhibitor of Tumor Necrosis Factor Receptor-1- and CD-95-induced Apoptosis

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7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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7 January 2021

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

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Inhibition of Fas-induced apoptosis by Bcl-2.

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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7 January 2021

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

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7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

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7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

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7 January 2021

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203824

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 November 2019

1049369141

0 references

1 reference