Benzodiazepine peptidomimetic inhibitors of farnesyltransferase (Q72145464)

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24 October 2019

title

Benzodiazepine peptidomimetic inhibitors of farnesyltransferase (English)

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24 October 2019

author name string

J C Marsters

1

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24 October 2019

R S McDowell

2

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24 October 2019

M E Reynolds

3

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24 October 2019

D A Oare

4

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24 October 2019

T C Somers

5

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24 October 2019

M S Stanley

6

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24 October 2019

T E Rawson

7

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24 October 2019

M E Struble

8

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24 October 2019

D J Burdick

9

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24 October 2019

K S Chan

10

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24 October 2019

language of work or name

English

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publication date

1 September 1994

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Bioorganic & Medicinal Chemistry

24 October 2019

published in

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24 October 2019

volume

2

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24 October 2019

issue

9

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24 October 2019

page(s)

949-957

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Growth factor signaling by receptor tyrosine kinases

24 October 2019

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All ras proteins are polyisoprenylated but only some are palmitoylated

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p21ras is modified by a farnesyl isoprenoid

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7 January 2021

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

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Steady-state kinetic mechanism of Ras farnesyl:protein transferase

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Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

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7 January 2021

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

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A geranylgeranyltransferase for rhoA p21 distinct from the farnesyltransferase for ras p21S.

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Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product

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7 January 2021

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

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7 January 2021

Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

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7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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Non-peptide ligands for peptide receptors

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Conformational constraints: nonpeptide beta-turn mimics

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Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution

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Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase

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7 January 2021

Pyrazole binding in crystalline binary and ternary complexes with liver alcohol dehydrogenase

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7 January 2021

Crystal structure determinations of coenzyme analogue and substrate complexes of liver alcohol dehydrogenase: binding of 1,4,5,6-tetrahydronicotinamide adenine dinucleotide and trans-4-(N,N-dimethylamino)cinnamaldehyde to the enzyme

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7 January 2021

High-resolution structure of an HIV zinc fingerlike domain via a new NMR-based distance geometry approach

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High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution

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Concepts and progress in the development of peptide mimetics

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7 January 2021

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

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7 January 2021

10.1016/S0968-0896(00)82044-1

Identifiers

DOI

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24 October 2019

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