In vitro mutagenesis of the mitochondrial leucyl-tRNA synthetase of S. cerevisiae reveals residues critical for its in vivo activities (Q68167353)

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22 September 2019

title

In vitro mutagenesis of the mitochondrial leucyl-tRNA synthetase of S. cerevisiae reveals residues critical for its in vivo activities (English)

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22 September 2019

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15 October 2022

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15 October 2022

author name string

G. Y. Li

1

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15 October 2022

C. J. Herbert

2

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15 October 2022

M. Labouesse

3

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P. P. Slonimski

4

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15 October 2022

language of work or name

English

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National Center for Biotechnology Information

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15 October 2022

publication date

1 July 1992

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full work available at URL

22 September 2019

http://link.springer.com/content/pdf/10.1007/BF00351744.pdf

file format

Portable Document Format

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http://link.springer.com/article/10.1007/BF00351744/fulltext.html

15 October 2022

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http://link.springer.com/content/pdf/10.1007/BF00351744

15 October 2022

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15 October 2022

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22 September 2019

volume

22

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22 September 2019

issue

1

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22 September 2019

page(s)

69-74

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Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants

22 September 2019

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/1611670

12 December 2020

The NAM2 proteins from S. cerevisiae and S. douglasii are mitochondrial leucyl-tRNA synthetases, and are involved in mRNA splicing

1 reference

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12 December 2020

Mitochondrial protein synthesis is required for maintenance of intact mitochondrial genomes in Saccharomyces cerevisiae

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12 December 2020

Long range control circuits within mitochondria and between nucleus and mitochondria. I. Methodology and phenomenology of suppressors

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12 December 2020

Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA.

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12 December 2020

Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs

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12 December 2020

The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA.

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12 December 2020

Protein encoded by the third intron of cytochrome b gene in Saccharomyces cerevisiae is an mRNA maturase. Analysis of mitochondrial mutants, RNA transcripts proteins and evolutionary relationships

1 reference

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12 December 2020

Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism

1 reference

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12 December 2020

Affinity labeling of aminoacyl-tRNA synthetases with adenosine triphosphopyridoxal: probing the Lys-Met-Ser-Lys-Ser signature sequence as the ATP-binding site in Escherichia coli methionyl-and valyl-tRNA synthetases

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12 December 2020

The yeast mitochondrial leucyl-tRNA synthetase is a splicing factor for the excision of several group I introns

1 reference

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12 December 2020

A mutation in yeast mitochondrial DNA results in a precise excision of the terminal intron of the cytochrome b gene

1 reference

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12 December 2020

Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

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12 December 2020

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA.

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12 December 2020

Long range control circuits within mitochondria and between nucleus and mitochondria. II. Genetic and biochemical analyses of suppressors which selectively alleviate the mitochondrial intron mutations

1 reference

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12 December 2020

Self-splicing of group I introns

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https://pubmed.ncbi.nlm.nih.gov/1611670

12 December 2020

A mitochondrial RNA maturase gene transferred to the yeast nucleus can control mitochondrial mRNA splicing

1 reference

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12 December 2020

Methionyl-tRNA synthetase from Escherichia coli: primary structure at the binding site for the 3'-end of tRNAfMet

1 reference

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12 December 2020

Sequence of introns and flanking exons in wild-type and box3 mutants of cytochrome b reveals an interlaced splicing protein coded by an intron

1 reference

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12 December 2020

Hydrogen bonding and biological specificity analysed by protein engineering

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12 December 2020

Two group I mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing

1 reference

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12 December 2020

Construction of a yeast strain devoid of mitochondrial introns and its use to screen nuclear genes involved in mitochondrial splicing

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12 December 2020

Critical sequences within mitochondrial introns: pleiotropic mRNA maturase and cis-dominant signals of the box intron controlling reductase and oxidase

1 reference

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12 December 2020

Mutations within an intron and its flanking sites: patterns of novel polypeptides generated by mutants in one segment of the cob-box region of yeast mitochondrial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/1611670

12 December 2020

A protein required for splicing group I introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof

1 reference

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12 December 2020

Evidence from cassette mutagenesis for a structure-function motif in a protein of unknown structure

1 reference

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12 December 2020

An mRNA maturase is encoded by the first intron of the mitochondrial gene for the subunit I of cytochrome oxidase in S. cerevisiae

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12 December 2020

The yeast nuclear gene NAM2 is essential for mitochondrial DNA integrity and can cure a mitochondrial RNA-maturase deficiency

1 reference

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12 December 2020

The Neurospora mitochondrial tyrosyl-tRNA synthetase is sufficient for group I intron splicing in vitro and uses the carboxy-terminal tRNA-binding domain along with other regions

1 reference

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12 December 2020

A family of low and high copy replicative, integrative and single-strandedS. cerevisiae/E. coli shuttle vectors

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12 December 2020

Efficient splicing of two yeast mitochondrial introns controlled by a nuclear-encoded maturase

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12 December 2020

A mutant of Saccharomyces cerevisiae defective for nuclear fusion

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12 December 2020

Transformation of intact yeast cells treated with alkali cations

1 reference

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12 December 2020

Identifiers

DOI

10.1007/BF00351744

1 reference

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22 September 2019

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