Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes (Q64235524)

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scientific article published on 17 February 2019

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English	Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes	scientific article published on 17 February 2019

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30 April 2020

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes (English)

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30 April 2020

lipopolysaccharide

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inflammasome complex

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based on heuristic

inferred from title

1

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4

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5

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6

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30 April 2020

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Yuhong He

2

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30 April 2020

Hao Ming

3

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17 February 2019

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30 April 2020

Journal of Diabetes Research

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2019

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8151836

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30 April 2020

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Creative Commons Attribution 4.0 International

17 February 2019

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copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6398034/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Myocardial depression during sepsis

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https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and acute coronary syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide pretreatment protects against ischemia/reperfusion injury via increase of HSP70 and inhibition of NF-κB

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sevoflurane combined with ATP activates caspase-1 and triggers caspase-1-dependent pyroptosis in murine J774 macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPS induces cardiomyocyte injury through calcium-sensing receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPS from P. gingivalis and hypoxia increases oxidative stress in periodontal ligament fibroblasts and contributes to periodontitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms in the pathogenesis of sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin-(1-7) Improves Liver Fibrosis by Regulating the NLRP3 Inflammasome via Redox Balance Modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate cell communication kick-starts pathogen-specific immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-induced myocardial dysfunction: pathophysiology and management

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide pretreatment promotes cardiac stem cell migration through heat shock protein 90-dependent β-catenin activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling: Revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulforaphane attenuates activation of NLRP3 and NLRC4 inflammasomes but not AIM2 inflammasome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism and Regulation of NLRP3 Inflammasome Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammasomes and its importance in viral infections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Emerging Role of Thioredoxin-Interacting Protein in Myocardial Ischemia/Reperfusion Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemia/Reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the pathophysiology and molecular basis of sepsis-associated organ dysfunction: Novel therapeutic implications and challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin alleviates inflammasome-induced pyroptosis through inhibiting NF-κB/GSDMD signal in mice adipose tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunopathology of sepsis and potential therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

microRNA-99a Reduces Lipopolysaccharide-Induced Oxidative Injury by Activating Notch Pathway in H9c2 Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Klotho protects the heart from hyperglycemia-induced injury by inactivating ROS and NF-κB-mediated inflammation both in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphenol AF negatively affects oocyte maturation of mouse in vitro through increasing oxidative stress and DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Edaravone attenuates lipopolysaccharide-induced acute respiratory distress syndrome associated early pulmonary fibrosis via amelioration of oxidative stress and transforming growth factor-β1/Smad3 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astragalus polysaccharide alleviates LPS-induced inflammation injury by regulating miR-127 in H9c2 cardiomyoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triptolide reduces ischemia/reperfusion injury in rats and H9C2 cells via inhibition of NF‑κB, ROS and the ERK1/2 pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Geniposide Attenuates LPS-Induced Injury via Up-Regulation of miR-145 in H9c2 Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NLRP9b attenuates acute lung injury through suppressing inflammation, apoptosis and oxidative stress in murine and cell models

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of ginsenoside metabolite compound K against diabetic nephropathy by inhibiting NLRP3 inflammasome activation and NF-κB/p38 signaling pathway in high-fat diet/streptozotocin-induced diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fmr1 protects cardiomyocytes against lipopolysaccharide-induced myocardial injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30911553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2019/8151836

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30 April 2020

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Europe PubMed Central

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30 April 2020

PubMed publication ID

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Europe PubMed Central

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30 April 2020

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