Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion (Q59065258)

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21 September 2019

title

Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion (English)

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21 September 2019

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7 October 2022

allele

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7 October 2022

exon

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7 October 2022

2

Rajewsky K

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21 September 2019

author name string

Kitamura D

series ordinal

1

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21 September 2019

language of work or name

English

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publication date

1 March 1992

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21 September 2019

12 March 1992

1 reference

National Center for Biotechnology Information

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7 October 2022

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21 September 2019

volume

356

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21 September 2019

issue

6365

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21 September 2019

page(s)

154-156

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Somatic generation of antibody diversity

21 September 2019

cites work

1 reference

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7 January 2021

Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu

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7 January 2021

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains

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7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

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7 January 2021

Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene

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7 January 2021

B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames

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7 January 2021

Immunoglobulin chain loss in hybridoma lines

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7 January 2021

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

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7 January 2021

Translation affects immunoglobulin mRNA stability

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Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

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The protecton: the unit of humoral immunity selected by evolution

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7 January 2021

Mu heavy chains can associate with a pseudo-light chain complex (ψL) in human pre-B cell lines

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7 January 2021

The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain

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7 January 2021

The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface

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7 January 2021

The omega/lambda 5 surrogate immunoglobulin light chain is expressed on the surface of transitional B lymphocytes in murine bone marrow

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7 January 2021

Light-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virus

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7 January 2021

A monoclonal antibody against Igh6-4 determinant

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7 January 2021

Monoclonal anti-allotype antibody towards BALB/c IgM. Analysis of specificity and site of a V-C crossover in recombinant strain BALB-Igh-Va/Igh-Cb

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7 January 2021

Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development

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7 January 2021

Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules.

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7 January 2021

Inhibition of antibody production at high cell density following mitogen stimulation and isotype switching in vitro

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7 January 2021

Localization of murine Ig-1b and Ig-1a (IgG 2a) allotypic determinants detected with monoclonal antibodies

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7 January 2021

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

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7 January 2021

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

1 reference

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7 January 2021

In vivo generation and function of B cells in the presence of a monoclonal anti-IgM antibody: implications for B cell tolerance

1 reference

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7 January 2021

The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

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7 January 2021

Stepwise intraclonal maturation of antibody affinity through somatic hypermutation

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7 January 2021

Identifiers

DOI

10.1038/356154A0

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1545868%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 September 2019

1036604129

0 references

1 reference