Combination of interferon-expressing oncolytic adenovirus with chemotherapy and radiation is highly synergistic in hamster model of pancreatic cancer. (Q55004955)

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scientific article published on 6 April 2018

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English	Combination of interferon-expressing oncolytic adenovirus with chemotherapy and radiation is highly synergistic in hamster model of pancreatic cancer.	scientific article published on 6 April 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Combination of interferon-expressing oncolytic adenovirus with chemotherapy and radiation is highly synergistic in hamster model of pancreatic cancer. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

oncolytic virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Amanda O Salzwedel

1

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Joohee Han

2

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Christopher J LaRocca

3

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Ryan Shanley

4

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Masato Yamamoto

5

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Julia Davydova

6

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

language of work or name

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publication date

6 April 2018

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

9

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

26

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

18041-18052

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

Combining Oncolytic Adenovirus with Radiation-A Paradigm for the Future of Radiosensitization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Cancer Statistics, 2017.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

The Efficacy of Oncolytic Adenovirus Is Mediated by T-cell Responses against Virus and Tumor in Syrian Hamster Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Oncolytic Virotherapy Increases the Detection of Microscopic Metastatic Disease at Time of Staging Laparoscopy for Pancreatic Adenocarcinoma

1 reference

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16 June 2018

Oncolytic viruses: finally delivering

1 reference

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16 June 2018

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

1 reference

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16 June 2018

Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Pancreatic cancer and FOLFIRINOX: a new era and new questions

1 reference

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16 June 2018

nab-Paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial.

1 reference

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16 June 2018

Role of neoadjuvant therapy in the management of pancreatic cancer: is the era of biomarker-directed therapy here?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Oncolytic adenoviruses: design, generation, and experimental procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Neoadjuvant interferon-based chemoradiation for borderline resectable and locally advanced pancreas cancer: a Phase II pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Generation of a novel, cyclooxygenase-2-targeted, interferon-expressing, conditionally replicative adenovirus for pancreatic cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Delivery of interferon alpha using a novel Cox2-controlled adenovirus for pancreatic cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Multicenter phase II trial of adjuvant therapy for resected pancreatic cancer using cisplatin, 5-fluorouracil, and interferon-alfa-2b-based chemoradiation: ACOSOG Trial Z05031.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Oncolytic adenoviral mutants with E1B19K gene deletions enhance gemcitabine-induced apoptosis in pancreatic carcinoma cells and anti-tumor efficacy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5915056

16 June 2018

Strength of the evidence: adjuvant therapy for resected pancreatic cancer

1 reference

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16 June 2018

Impact of interferon-alpha in combined chemoradioimmunotherapy for pancreatic adenocarcinoma (CapRI): first data from the immunomonitoring

1 reference

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

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16 June 2018

Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors.

1 reference

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16 June 2018

Adenovirus-mediated interferon alpha gene transfer induces regional direct cytotoxicity and possible systemic immunity against pancreatic cancer

1 reference

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16 June 2018

Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma -- CapRI: study protocol [ISRCTN62866759]

1 reference

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16 June 2018

New pharmacokinetic and pharmacodynamic tools for interferon-alpha (IFN-alpha) treatment of human cancer.

1 reference

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16 June 2018

The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner

1 reference

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16 June 2018

Infectivity-enhanced cyclooxygenase-2-based conditionally replicative adenoviruses for esophageal adenocarcinoma treatment

1 reference

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16 June 2018

Interferons: mechanisms of action and clinical applications

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PKR; a sentinel kinase for cellular stress

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Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase

1 reference

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An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

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Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob

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Clinical Pharmacokinetics of Interferons

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The current status of oncolytic viral therapy for head and neck cancer.

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Interferon-based Adjuvant Chemoradiation for Resected Pancreatic Head Cancer: Long-term Follow-up of the Virginia Mason Protocol

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13 August 2018

Adjuvant interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: a single-institution phase II study

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13 August 2018

Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma

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13 August 2018

Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma

1 reference

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Interaction of fluorouracil and interferon in human colon cancer cell lines: cytotoxic and cytokinetic effects

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of radiation effects by alpha interferon in the treatment of small cell carcinoma of the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/29719589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.24710

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5915056

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