Extracellular acidification stimulates IL-6 production and Ca(2+) mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells. (Q54418487)

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English	Extracellular acidification stimulates IL-6 production and Ca(2+) mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Extracellular acidification stimulates IL-6 production and Ca(2+) mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells. (English)

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

author name string

Isao Ichimonji

1

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Hideaki Tomura

2

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Chihiro Mogi

3

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Koichi Sato

4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Haruka Aoki

5

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PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Takeshi Hisada

6

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Europe PubMed Central

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29 May 2018

http://europepmc.org/abstract/MED/20656891

Kunio Dobashi

7

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29 May 2018

http://europepmc.org/abstract/MED/20656891

Tamotsu Ishizuka

8

1 reference

Europe PubMed Central

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29 May 2018

http://europepmc.org/abstract/MED/20656891

Masatomo Mori

9

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Fumikazu Okajima

10

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

publication date

23 July 2010

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

American Journal of Physiology - Lung Cellular and Molecular Physiology

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

299

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PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

4

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PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

L567-77

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

Innate cells and T helper 2 cell immunity in airway inflammation

1 reference

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21 January 2018

Smooth muscle cell calcium activation mechanisms

1 reference

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21 January 2018

Signaling and regulation of G protein-coupled receptors in airway smooth muscle

1 reference

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21 January 2018

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Airway smooth muscle as an immunomodulatory cell

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21 January 2018

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Targeting G protein-coupled receptor signaling in asthma

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Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity

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21 January 2018

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

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21 January 2018

Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation

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21 January 2018

Pathological role of IL-6 in the experimental allergic bronchial asthma in mice

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21 January 2018

Airway remodeling in asthma

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21 January 2018

Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor

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Peritoneal acidosis mediates immunoprotection in laparoscopic surgery

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21 January 2018

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6

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21 January 2018

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.

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21 January 2018

Endogenous airway acidification. Implications for asthma pathophysiology

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21 January 2018

Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor

1 reference

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21 January 2018

Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells

1 reference

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21 January 2018

Sphingosine 1-phosphate inhibits migration and RANTES production in human bronchial smooth muscle cells

1 reference

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21 January 2018

Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner

1 reference

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21 January 2018

Role of TRPV1 in inflammation-induced airway hypersensitivity

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21 January 2018

Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1

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21 January 2018

Proton-sensing G-protein-coupled receptors

1 reference

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21 January 2018

Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism

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21 January 2018

Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages.

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21 January 2018

Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation

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21 January 2018

G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine

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21 January 2018

IL-6 is required for airway mucus production induced by inhaled fungal allergens

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21 January 2018

Enhanced airway inflammation and decreased subepithelial fibrosis in interleukin 6-deficient mice following chronic exposure to aerosolized antigen.

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Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells

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Acid stress in the pathology of asthma.

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Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms

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Cyclooxygenase-2 expression and prostaglandin E2 production in response to acidic pH through OGR1 in a human osteoblastic cell line

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TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor

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Validation of the Anti-Inflammatory Properties of Small-Molecule I B Kinase (IKK)-2 Inhibitors by Comparison with Adenoviral-Mediated Delivery of Dominant-Negative IKK1 and IKK2 in Human Airways Smooth Muscle

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Identifiers

10.1152/AJPLUNG.00415.2009

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/20656891

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