Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome. (Q53639289)

http://europepmc.org/abstract/PMC/5987200

1 July 2018

title

Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome. (English)

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http://europepmc.org/abstract/PMC/5987200

1 July 2018

0 references

Zhonghui Xu

7

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Roberto Romero

object named as

Roberto Romero

3

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Tinnakorn Chaiworapongsa

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Tinnakorn Chaiworapongsa

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Sonia S Hassan

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http://europepmc.org/abstract/PMC/5987200

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Adi L Tarca

13

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Adi L Tarca

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http://europepmc.org/abstract/PMC/5987200

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author name string

Szilvia Szabo

1

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http://europepmc.org/abstract/PMC/5987200

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Meera Mody

2

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http://europepmc.org/abstract/PMC/5987200

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Yi Xu

4

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http://europepmc.org/abstract/PMC/5987200

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Katalin Karaszi

5

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http://europepmc.org/abstract/PMC/5987200

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Noemi Mihalik

6

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http://europepmc.org/abstract/PMC/5987200

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Gaurav Bhatti

8

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http://europepmc.org/abstract/PMC/5987200

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Tibor Fule

9

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http://europepmc.org/abstract/PMC/5987200

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Petronella Hupuczi

10

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http://europepmc.org/abstract/PMC/5987200

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Tibor Krenacs

11

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http://europepmc.org/abstract/PMC/5987200

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Janos Rigo

12

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http://europepmc.org/abstract/PMC/5987200

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Ilona Kovalszky

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http://europepmc.org/abstract/PMC/5987200

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Zoltan Papp

17

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http://europepmc.org/abstract/PMC/5987200

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Nandor Gabor Than

18

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http://europepmc.org/abstract/PMC/5987200

1 July 2018

publication date

13 January 2015

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http://europepmc.org/abstract/PMC/5987200

1 July 2018

published in

Pathology Oncology Research

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http://europepmc.org/abstract/PMC/5987200

1 July 2018

volume

21

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http://europepmc.org/abstract/PMC/5987200

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issue

3

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http://europepmc.org/abstract/PMC/5987200

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page(s)

659-668

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http://europepmc.org/abstract/PMC/5987200

1 July 2018

cites work

In vivo experiments reveal the good, the bad and the ugly faces of sFlt-1 in pregnancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Opposing role of JNK-p38 kinase and ERK1/2 in hydrogen peroxide-induced oxidative damage of human trophoblast-like JEG-3 cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

IFPA Senior Award Lecture: making sense of pre-eclampsia - two placental causes of preeclampsia?

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Differentially expressed genes in the pre-eclamptic placenta: a systematic review and meta-analysis.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Villous trophoblast apoptosis is elevated and restricted to cytotrophoblasts in pregnancies complicated by preeclampsia, IUGR, or preeclampsia with IUGR.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

NFκB and JNK/MAPK activation mediates the production of major macrophage- or dendritic cell-recruiting chemokine in human first trimester decidual cells in response to proinflammatory stimuli

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Cross talk between cAMP and p38 MAPK pathways in the induction of leptin by hCG in human placental syncytiotrophoblasts

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

The "Great Obstetrical Syndromes" are associated with disorders of deep placentation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Microarray profiling reveals that placental transcriptomes of early-onset HELLP syndrome and preeclampsia are similar

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental origins of preeclampsia: challenging the current hypothesis

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental pathology: a systematic approach with clinical correlations

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Oxidative stress, gene expression, and protein changes induced in the human placenta during labor

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Soluble endoglin contributes to the pathogenesis of preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Latest advances in understanding preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Molecular evidence of placental hypoxia in preeclampsia.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

The human cytotrophoblastic cell, a mononuclear chameleon

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

An analysis using DNA microarray of the time course of gene expression during syncytialization of a human placental cell line (BeWo).

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Decreased placental GCM1 (glial cells missing) gene expression in pre-eclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Subclassification of preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Phenotypic and metabolic characteristics of monocytes and granulocytes in preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental debris, oxidative stress and pre-eclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Hypomethylation of the LEP gene in placenta and elevated maternal leptin concentration in early onset pre-eclampsia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Placental expression of VEGF family mRNA in adverse pregnancy outcomes.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Apoptosis, proliferation and Fas ligand expression in placental trophoblast from pregnancies complicated by HELLP syndrome or pre-eclampsia.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Gabor Than Award Lecture 2008: pre-eclampsia - from placental oxidative stress to maternal endothelial dysfunction

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Gabor Than Award Lecture 2006: pre-eclampsia and villous trophoblast turnover: perspectives and possibilities

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Expression of the proliferation marker Ki-67 and of p53 tumor protein in trophoblastic tissue of preeclamptic, HELLP, and intrauterine growth-restricted pregnancies.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Preeclampsia is associated with impaired regulation of the placental nitric oxide-cyclic guanosine monophosphate pathway by corticotropin-releasing hormone (CRH) and CRH-related peptides

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

The frequency and severity of placental findings in women with preeclampsia are gestational age dependent

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

The concentration of circulating corticotropin-releasing hormone mRNA in maternal plasma is increased in preeclampsia.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Microarray analysis of trophoblast differentiation: gene expression reprogramming in key gene function categories.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987200

Early-Onset Preeclampsia and HELLP Syndrome: An Overview

13 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12253-014-9872-9

Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12253-014-9872-9

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1007%2FS12253-014-9872-9

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/25583406

12 December 2020

Morphological changes in the utero-placental bed in pregnancy hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25583406

12 December 2020

Expression of BCL-2, BAX and BAK in the Trophoblast Layer of the Term Human Placenta: a Unique Model of Apoptosis within a Syncytium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25583406

12 December 2020

Apoptosis: Molecular Control of Placental Function—A Workshop Report

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25583406

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/25583406

1 reference

12 December 2020

10.1007/S12253-014-9872-9

Identifiers

DOI

1 reference

http://europepmc.org/abstract/PMC/5987200

1 July 2018

PMC publication ID

5987200

1 reference

http://europepmc.org/abstract/PMC/5987200

1 July 2018

PubMed publication ID

25583406

1 reference