Carbonic anhydrase 4 (Q5038044)

http://www.ebi.ac.uk/interpro/protein/P22748

Alpha carbonic anhydrase domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P22748

Alpha carbonic anhydrase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbonic anhydrase, alpha-class, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

1 reference

8 April 2019

protein binding

IPI

1 reference

8 April 2019

Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

IPI

lyase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

1 reference

8 April 2019

carbonate dehydratase activity

Human carbonic anhydrase IV: cDNA cloning, sequence comparison, and expression in COS cell membranes

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

rough endoplasmic reticulum

cell component

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

Golgi apparatus

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

membrane

Membrane-associated carbonic anhydrase purified from bovine lung

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

secretory granule membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

anchored component of plasma membrane

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

8 April 2019

Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

transport vesicle membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

cell surface

1 reference

8 April 2019

Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

brush border membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

trans-Golgi network

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

basolateral plasma membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

apical plasma membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

anchored component of external side of plasma membrane

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

perinuclear region of cytoplasm

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

extracellular exosome

5 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

26 September 2017

Identification and proteomic profiling of exosomes in human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

endoplasmic reticulum-Golgi intermediate compartment

1 reference

8 April 2019

Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

extracellular exosome

Identification and proteomic profiling of exosomes in human urine

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

HDA

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

HDA

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22748

one-carbon metabolic process

HDA

biological process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22748&geneProductId=UniProtKB:P22748

1 reference

26 September 2017

physically interacts with

1 reference

6792

17 August 2016

1 reference

7147

17 August 2016

1 reference

6807

17 August 2016

1 reference

6828

17 August 2016

1 reference

6849

English

http://purl.uniprot.org/uniprot/P22748

17 August 2016

Gene Atlas image

PBB GE CA4 206209 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

Carbonic anhydrase, alpha-class, conserved site

Identifiers.org

has part(s)

1 reference

http://www.ebi.ac.uk/interpro/protein/P22748

Alpha carbonic anhydrase domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P22748

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023