A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones (Q48829389)

15 February 2018

http://europepmc.org/abstract/MED/9003561

title

A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones (English)

1 reference

15 February 2018

http://europepmc.org/abstract/MED/9003561

author name string

Kew JN

series ordinal

1

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15 February 2018

http://europepmc.org/abstract/MED/9003561

Trube G

series ordinal

2

1 reference

15 February 2018

http://europepmc.org/abstract/MED/9003561

Kemp JA

series ordinal

3

1 reference

15 February 2018

http://europepmc.org/abstract/MED/9003561

language of work or name

English

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publication date

1 December 1996

1 reference

15 February 2018

http://europepmc.org/abstract/MED/9003561

published in

Journal of Physiology

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15 February 2018

http://europepmc.org/abstract/MED/9003561

volume

497 ( Pt 3)

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15 February 2018

http://europepmc.org/abstract/MED/9003561

page(s)

761-772

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15 February 2018

http://europepmc.org/abstract/MED/9003561

cites work

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Polyamine and ifenprodil interactions with the NMDA receptor's glycine site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

NMDA channel behavior depends on agonist affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Molecular diversity of the NMDA receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

The neuroprotective properties of ifenprodil, a novel NMDA receptor antagonist, in neuronal cell culture toxicity studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Interactions between the glycine and glutamate binding sites of the NMDA receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Both open and closed NMDA receptor channels desensitize

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

N-methyl-D-aspartic acid receptor structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Subtypes of NMDA receptor in neurones cultured from rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9‐aminoacridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Desensitization of N-methyl-D-aspartate receptors: a problem of interpretation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Burst kinetics of single NMDA receptor currents in cell-attached patches from rat brain cortical neurons in culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

NMDA receptor redox sites: are they targets for selective neuronal protection?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Magnesium gates glutamate-activated channels in mouse central neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Is the discriminative stimulus produced by phencyclidine due to an interaction with N-methyl-D-aspartate receptors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003561

12 December 2020

10.1113/JPHYSIOL.1996.SP021807

Identifiers

DOI

1 reference

15 February 2018

http://europepmc.org/abstract/MED/9003561

PMC publication ID

1160972

0 references

1 reference

15 February 2018