Neuroprotection in Alzheimer's disease - new strategies for treatment. (Q48491933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16787838%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Neuroprotection in Alzheimer's disease - new strategies for treatment (English)

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25 December 2019

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1

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25 December 2019

1

A Nordberg

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12 February 2018

http://europepmc.org/abstract/MED/16787838

publication date

1 January 2000

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25 December 2019

published in

Neurotoxicity Research

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25 December 2019

volume

2

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25 December 2019

issue

2-3

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25 December 2019

page(s)

157-165

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Neuropsychiatric aspects of Alzheimer's disease: the cholinergic hypothesis revisited

25 December 2019

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Nicotine inhibits amyloid formation by the beta-peptide.

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12 December 2020

Vitamin E protects nerve cells from amyloid beta protein toxicity

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12 December 2020

Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease

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12 December 2020

Imaging of nicotinic and muscarinic receptors in Alzheimer's disease: effect of tacrine treatment

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12 December 2020

Neuroreceptor changes in Alzheimer disease

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12 December 2020

Oral tetrahydroaminoacridine treatment of Alzheimer's disease evaluated clinically and by regional cerebral blood flow and EEG.

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12 December 2020

Beta-amyloid peptides as direct cholinergic neuromodulators: a missing link?

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12 December 2020

Biological markers and the cholinergic hypothesis in Alzheimer's disease

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12 December 2020

Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist

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12 December 2020

Longitudinal changes in quantitative EEG during long-term tacrine treatment of patients with Alzheimer's disease.

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease.

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Long-term effects of tacrine on regional cerebral blood flow changes in Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

beta-Amyloid precursor protein and Alzheimer's disease: the peptide plot thickens

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

The nerve growth factor 35 years later

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

NGF in CNS: experimental data and clinical implications

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Nonsteroidal anti-inflammatory drugs and cognitive function: do they have a beneficial or deleterious effect?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

The effect of estrogen replacement therapy on cognitive function in women: a critical review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Inflammatory mechanisms in Alzheimer's disease.

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Attenuation of beta-amyloid neurotoxicity in vitro by potassium-induced depolarization

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Excitotoxic cell death

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

NGF and the treatment of Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Oxidative damage in Alzheimer's

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Cholinesterase inhibitors increase secretion of APPs in rat brain cortex

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Estrogen deficiency and risk of Alzheimer's disease in women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Tacrine restores cholinergic nicotinic receptors and glucose metabolism in Alzheimer patients as visualized by positron emission tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Evolution of neuronal changes in the course of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

The female sex hormone oestrogen as a neuroprotectant

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Long-term tacrine treatment in three mild Alzheimer patients: effects on nicotinic receptors, cerebral blood flow, glucose metabolism, EEG, and cognitive abilities.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Regulation of amyloid precursor protein cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Enhanced Release of Secreted Form of Alzheimer’s Amyloid Precursor Protein from PC12 Cells by Nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Cholinesterase inhibitors in the treatment of Alzheimer's disease: a comparison of tolerability and pharmacology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 fragment, glutamate, and hydrogen peroxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Smoking and Alzheimer's disease: a review of the epidemiological evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Beta-estradiol attenuate amyloid beta-peptide toxicity via nicotinic receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Does amyloid precede paired helical filaments in the senile plaque? A study of 15 cases with graded intellectual status in aging and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Nicotine modulates the neurotoxic effect of beta-amyloid protein(25-35)) in hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains--in vivo assessment using positron emission tomography.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Amyloidogenic processing of Alzheimer's amyloid precursor protein in vitro and its modulation by metal ions and tacrine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Genetic and environmental aspects of the role of nicotinic receptors in neurodegenerative disorders: emphasis on Alzheimer's disease and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Neuroprotective and memory-related actions of novel alpha-7 nicotinic agents with different mixed agonist/antagonist properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

Protective effect of alpha-tocopherol on ischemic neuronal damage in the gerbil hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787838

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/16787838

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03033791

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16787838%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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