Human immunoglobulin D segments encoded in tandem multigenic families (Q48407051)

11 February 2018

http://europepmc.org/abstract/MED/7312051

title

Human immunoglobulin D segments encoded in tandem multigenic families (English)

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29 April 2024

3

Korsmeyer S

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11 February 2018

http://europepmc.org/abstract/MED/7312051

Jeffrey Ravetch

2

object named as

J. V. Ravetch

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author name string

U. Siebenlist

1

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S. Korsmeyer

3

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T. Waldmann

4

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P. Leder

5

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language of work or name

English

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publication date

1 December 1981

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11 February 2018

http://europepmc.org/abstract/MED/7312051

17 December 1981

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7312051

full work available at URL

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http://www.nature.com/articles/294631a0

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http://www.nature.com/articles/294631a0.pdf

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file format

Portable Document Format

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29 April 2024

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11 February 2018

http://europepmc.org/abstract/MED/7312051

volume

294

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11 February 2018

http://europepmc.org/abstract/MED/7312051

issue

5842

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11 February 2018

http://europepmc.org/abstract/MED/7312051

page(s)

631-635

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11 February 2018

http://europepmc.org/abstract/MED/7312051

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A complete immunoglobulin gene is created by somatic recombination

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The arrangement and rearrangement of antibody genes

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7 January 2021

A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

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7 January 2021

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

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7 January 2021

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

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7 January 2021

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Mouse pre-B cells synthesize and secrete mu heavy chains but not light chains

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7 January 2021

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene

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7 January 2021

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

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7 January 2021

The joining of V and J gene segments creates antibody diversity

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Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments

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7 January 2021

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

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Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

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Detection of specific sequences among DNA fragments separated by gel electrophoresis

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Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments

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Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region

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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

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7 January 2021

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody

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7 January 2021

Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity

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7 January 2021

Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/294631A0

1 reference

11 February 2018

http://europepmc.org/abstract/MED/7312051

Dimensions Publication ID

1011004798

0 references

1 reference

11 February 2018