TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup (Q46838481)

25 December 2017

http://europepmc.org/abstract/MED/28899973

title

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup (English)

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25 December 2017

http://europepmc.org/abstract/MED/28899973

16

Ashley E Ross

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13

Edward M Schaeffer

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11

Elai Davicioni

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Nicholas Erho

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9

Mohammed Alshalalfa

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20

Felix Y Feng

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3

Myles Brown

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author name string

David P Labbé

1

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http://europepmc.org/abstract/MED/28899973

Christopher J Sweeney

2

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http://europepmc.org/abstract/MED/28899973

Phillip Galbo

4

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http://europepmc.org/abstract/MED/28899973

Spencer Rosario

5

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http://europepmc.org/abstract/MED/28899973

Kristine M Wadosky

6

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http://europepmc.org/abstract/MED/28899973

Sheng-Yu Ku

7

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http://europepmc.org/abstract/MED/28899973

Martin Sjöström

8

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R Jeffrey Karnes

12

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Robert B Jenkins

14

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http://europepmc.org/abstract/MED/28899973

Robert B Den

15

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http://europepmc.org/abstract/MED/28899973

Michaela Bowden

17

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http://europepmc.org/abstract/MED/28899973

Ying Huang

18

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http://europepmc.org/abstract/MED/28899973

Kathryn P Gray

19

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http://europepmc.org/abstract/MED/28899973

Daniel E Spratt

21

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http://europepmc.org/abstract/MED/28899973

David W Goodrich

22

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http://europepmc.org/abstract/MED/28899973

Kevin H Eng

23

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http://europepmc.org/abstract/MED/28899973

Leigh Ellis

24

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http://europepmc.org/abstract/MED/28899973

language of work or name

English

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publication date

12 September 2017

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25 December 2017

http://europepmc.org/abstract/MED/28899973

published in

Clinical Cancer Research

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25 December 2017

http://europepmc.org/abstract/MED/28899973

volume

23

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http://europepmc.org/abstract/MED/28899973

issue

22

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http://europepmc.org/abstract/MED/28899973

page(s)

7072-7083

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25 December 2017

http://europepmc.org/abstract/MED/28899973

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5690819

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Utilization of a Genomic Classifier for Prediction of Metastasis Following Salvage Radiation Therapy after Radical Prostatectomy

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Validation of a Genomic Classifier for Predicting Post-Prostatectomy Recurrence in a Community Based Health Care Setting

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Advanced neuroendocrine prostate tumors regress to stemness

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The Molecular Taxonomy of Primary Prostate Cancer

3 November 2018

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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

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DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

3 November 2018

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A basal stem cell signature identifies aggressive prostate cancer phenotypes.

3 November 2018

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Overexpression of enhancer of zeste homolog 2 (EZH2) characterizes an aggressive subset of prostate cancers and predicts patient prognosis independently from pre- and postoperatively assessed clinicopathological parameters

3 November 2018

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Tissue-based Genomics Augments Post-prostatectomy Risk Stratification in a Natural History Cohort of Intermediate- and High-Risk Men.

3 November 2018

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Determination of synthetic lethal interactions to provide therapeutic direction to end aggressive prostate cancer

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Genomic Predictors of Outcome in Prostate Cancer

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Polycomb-mediated silencing in neuroendocrine prostate cancer.

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Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer

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3 November 2018

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A Biopsy-based 17-gene Genomic Prostate Score Predicts Recurrence After Radical Prostatectomy and Adverse Surgical Pathology in a Racially Diverse Population of Men with Clinically Low- and Intermediate-risk Prostate Cancer

3 November 2018

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3 November 2018

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Evaluation of protein biomarkers of prostate cancer aggressiveness

3 November 2018

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Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma

3 November 2018

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3 November 2018

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A molecular signature predictive of indolent prostate cancer

3 November 2018

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Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy

3 November 2018

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Comprehensive molecular characterization of clear cell renal cell carcinoma

3 November 2018

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Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk patient population.

3 November 2018

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Validation of a cell-cycle progression gene panel to improve risk stratification in a contemporary prostatectomy cohort

3 November 2018

1 reference

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Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer

3 November 2018

1 reference

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

3 November 2018

1 reference

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A single-sample microarray normalization method to facilitate personalized-medicine workflows.

3 November 2018

1 reference

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Beyond PSA: the next generation of prostate cancer biomarkers

3 November 2018

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ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Modeling a lethal prostate cancer variant with small-cell carcinoma features

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study.

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

The ability of biomarkers to predict systemic progression in men with high-risk prostate cancer treated surgically is dependent on ERG status.

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Novel diagnostic biomarkers for prostate cancer

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Increased mutagenesis and unique mutation signature associated with mitotic gene conversion

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Integrative genomic profiling of human prostate cancer

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Gene panel model predictive of outcome in men at high-risk of systemic progression and death from prostate cancer after radical retropubic prostatectomy

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5690819

10.1158/1078-0432.CCR-17-0413

3 November 2018

Identifiers

DOI

1 reference

25 December 2017

http://europepmc.org/abstract/MED/28899973

PMC publication ID

5690819

0 references

1 reference

25 December 2017