NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. (Q46750110)

PubMed publication ID

16221845

24 December 2017

http://europepmc.org/abstract/MED/16221845

title

NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production (English)

1 reference

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12 May 2020

1

Sylvain E Lesné

1 reference

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12 May 2020

Carine Ali

2

1 reference

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12 May 2020

Eric T MacKenzie

5

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Catherine Marchand-Leroux

12 May 2020

8

1 reference

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12 May 2020

Denis Vivien

9

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12 May 2020

Alain Buisson

10

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12 May 2020

3

Cecília Gabriel

1 reference

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12 May 2020

author name string

Nicole Croci

4

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12 May 2020

Charles G Glabe

6

1 reference

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12 May 2020

Michel Plotkine

7

1 reference

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12 May 2020

language of work or name

English

0 references

publication date

1 October 2005

1 reference

PubMed publication ID

16221845

24 December 2017

http://europepmc.org/abstract/MED/16221845

published in

Journal of Neuroscience

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12 May 2020

volume

25

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12 May 2020

issue

41

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12 May 2020

page(s)

9367-9377

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Caspases as treatment targets in stroke and neurodegenerative diseases

12 May 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

The changing landscape of ischaemic brain injury mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Head injury and the risk of AD in the MIRAGE study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Proteomics of the nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Calcium regulation of neuronal gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Progressive decrease of amyloid precursor protein carboxy terminal fragments (APP-CTFs), associated with tau pathology stages, in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Amyloid β accumulation in axons after traumatic brain injury in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Detrimental Role of Bradykinin B2Receptor in a Murine Model of Diffuse Brain Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Pathophysiology of cerebral ischemia and brain trauma: similarities and differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

βA4 amyloid protein deposition in brain after head trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Alzheimer's disease: glycolytic pretreatment dramatically enhances immunolabeling of senile plaques and cerebrovascular amyloid substance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Glutamate neurotoxicity and diseases of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Alzheimer's disease: a study of epidemiological aspects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Calcium: still center-stage in hypoxic-ischemic neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Head injury, amyloid β and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Spatial resolution of the primary beta-amyloidogenic process induced in postischemic hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Beta-amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons: selective increase of mRNAs encoding a Kunitz protease inhibitor domain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

beta-Amyloid converts an acute phase injury response to chronic injury responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

The effects of additional pathology on the cognitive deficit in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiop

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Post-ischemic changes in the expression of Alzheimer's APP isoforms in rat cerebral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

beta-Amyloid precursor protein and ss-amyloid peptide immunoreactivity in the rat brain after middle cerebral artery occlusion: effect of age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

Transgenic mice expressing Alzheimer amyloid precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221845

12 December 2020

10.1523/JNEUROSCI.0849-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725703&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725703&resulttype=core&format=json

12 May 2020

PubMed publication ID

16221845

1 reference