Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction (Q46517603)

22 December 2017

http://europepmc.org/abstract/MED/9601640

title

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction (English)

1 reference

22 December 2017

http://europepmc.org/abstract/MED/9601640

author name string

Holsinger LJ

1

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Graef IA

2

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Swat W

3

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Chi T

4

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Bautista DM

5

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Davidson L

6

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22 December 2017

http://europepmc.org/abstract/MED/9601640

Lewis RS

7

1 reference

22 December 2017

http://europepmc.org/abstract/MED/9601640

Alt FW

8

1 reference

22 December 2017

http://europepmc.org/abstract/MED/9601640

Crabtree GR

9

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22 December 2017

http://europepmc.org/abstract/MED/9601640

language of work or name

English

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publication date

1 May 1998

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22 December 2017

http://europepmc.org/abstract/MED/9601640

published in

Current Biology

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22 December 2017

http://europepmc.org/abstract/MED/9601640

volume

8

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22 December 2017

http://europepmc.org/abstract/MED/9601640

issue

10

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22 December 2017

http://europepmc.org/abstract/MED/9601640

page(s)

563-572

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22 December 2017

http://europepmc.org/abstract/MED/9601640

1 reference

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Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

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7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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A functional T-cell receptor signaling pathway is required for p95vav activity

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Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

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Signal transduction in T lymphocytes using a conditional allele of Sos

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

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Rho Family GTPases Bind to Phosphoinositide Kinases

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

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7 January 2021

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

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7 January 2021

Normal Distribution, Patching and Capping of Lymphocyte Surface Immunoglobulin studied by Electron Microscopy

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Inhibition and reversal of capping by cytochalasin B, yinblastine and colchicine

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7 January 2021

Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography

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Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

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7 January 2021

Selective modulation of protein kinase C-theta during T-cell activation

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The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

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Co-capping of ras proteins with surface immunoglobulins in B lymphocytes

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7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

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A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

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Stimulation of p21 ras upon T-cell activation

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Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin

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Identifiers

DOI

1 reference

22 December 2017

http://europepmc.org/abstract/MED/9601640

1 reference

22 December 2017