Value of targeted treatment for testicular cancer: from molecular approaches to clinical possibilities (Q46512637)

22 December 2017

http://europepmc.org/abstract/MED/18587552

review article

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title

Value of targeted treatment for testicular cancer: from molecular approaches to clinical possibilities (English)

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22 December 2017

http://europepmc.org/abstract/MED/18587552

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A Martinschek

1

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22 December 2017

http://europepmc.org/abstract/MED/18587552

C G Ruf

series ordinal

2

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22 December 2017

http://europepmc.org/abstract/MED/18587552

C Sparwasser

series ordinal

3

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22 December 2017

http://europepmc.org/abstract/MED/18587552

H U Schmelz

series ordinal

4

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22 December 2017

http://europepmc.org/abstract/MED/18587552

language of work or name

German

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publication date

1 October 2008

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22 December 2017

http://europepmc.org/abstract/MED/18587552

published in

Der Urologe. Ausg. A

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22 December 2017

http://europepmc.org/abstract/MED/18587552

volume

47

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22 December 2017

http://europepmc.org/abstract/MED/18587552

issue

10

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22 December 2017

http://europepmc.org/abstract/MED/18587552

page(s)

1328-1333

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22 December 2017

http://europepmc.org/abstract/MED/18587552

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Fas and Fas ligand expression in fetal and adult human testis with normal or deranged spermatogenesis

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The future of therapy for nonseminomatous germ cell tumors.

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Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.

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Expression of KIT and epidermal growth factor receptor in chemotherapy refractory non-seminomatous germ-cell tumors.

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12 December 2020

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TCL1: a new drug target in lymphoid and germ-cell malignancies?

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12 December 2020

The Fas system is a key regulator of germ cell apoptosis in the testis

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Update on angiogenesis inhibitors

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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12 December 2020

[Diagnosis and therapy of testicular tumors]

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12 December 2020

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12 December 2020

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12 December 2020

The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis

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12 December 2020

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Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation

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12 December 2020

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12 December 2020

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

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12 December 2020

The biochemistry of apoptosis

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12 December 2020

Curing metastatic testicular cancer

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12 December 2020

Gonadal expression of c-kit encoded at the W locus of the mouse

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12 December 2020

Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis

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12 December 2020

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

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12 December 2020

Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer

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12 December 2020

New insights into testicular germ cell tumorigenesis from gene expression profiling.

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Transition from in situ to invasive testicular germ cell neoplasia is associated with the loss of p21 and gain of mdm-2 expression.

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12 December 2020

A p53 dose-response relationship for sensitivity to DNA damage in isogenic teratocarcinoma cells

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12 December 2020

Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic

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12 December 2020

Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview

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12 December 2020

Imatinib mesylate inhibits Leydig cell tumor growth: evidence for in vitro and in vivo activity.

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12 December 2020

Genome profiles of familial/bilateral and sporadic testicular germ cell tumors

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Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines

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12 December 2020

The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology.

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K-ras oncogene codon 12 point mutations in testicular cancer

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The rho/rho-kinase pathway is involved in the progression of testicular germ cell tumour.

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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Genetics and biology of adult human male germ cell tumors.

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12 December 2020

Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies

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12 December 2020

The emerging role of epidermal growth factor receptor inhibitors in ovarian cancer

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12 December 2020

A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer

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12 December 2020

D-type cyclins in adult human testis and testicular cancer: relation to cell type, proliferation, differentiation, and malignancy

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12 December 2020

p53-dependent cell death/apoptosis is required for a productive adenovirus infection

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12 December 2020

P53 and Fas are sequential mechanisms of testicular germ cell apoptosis

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12 December 2020

Expression of Fas and Fas ligand in the testes and testicular germ cell tumors: an immunohistochemical study

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12 December 2020

Imatinib mesilate for the treatment of gastrointestinal stromal tumour

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12 December 2020

Angiogenic inhibitors: a new therapeutic strategy in oncology

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12 December 2020

Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells

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12 December 2020

Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors

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12 December 2020

The correlation of P53 protein expression with proliferative activity and occult metastases in clinical stage I non-seminomatous germ cell tumors of the testis

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12 December 2020

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

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12 December 2020

Molecular markers in testicular germ cell tumors--objects of clinical research or close to becoming clinical tools?

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12 December 2020

Gene expression profiling in seminoma and nonseminoma.

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12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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12 December 2020

The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors

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12 December 2020

Poor prognosis germ cell tumors: current status and future directions

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12 December 2020

Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio.

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

10.1007/S00120-008-1750-1

Identifiers

DOI

1 reference

22 December 2017

http://europepmc.org/abstract/MED/18587552

1 reference

22 December 2017