Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity. (Q46461062)

PubMed publication ID

15858065

22 December 2017

http://europepmc.org/abstract/MED/15858065

title

Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity (English)

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12 May 2020

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6

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12 May 2020

author name string

Shengwei Zou

1

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12 May 2020

Lei Li

2

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12 May 2020

Lin Pei

3

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12 May 2020

Brian Vukusic

4

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12 May 2020

Hubert H M Van Tol

5

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12 May 2020

Qi Wan

7

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12 May 2020

Fang Liu

8

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12 May 2020

language of work or name

English

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publication date

1 April 2005

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PubMed publication ID

15858065

22 December 2017

http://europepmc.org/abstract/MED/15858065

published in

Journal of Neuroscience

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12 May 2020

volume

25

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12 May 2020

issue

17

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12 May 2020

page(s)

4385-4395

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Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1

12 May 2020

cites work

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12 December 2020

Low expression of GluR2 AMPA receptor subunit protein by human motor neurons

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12 December 2020

Effects of reciprocal chimeras between the C-terminal portion of third intracellular loops of the human dopamine D2 and D3 receptors

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12 December 2020

Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism.

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12 December 2020

D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors

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12 December 2020

Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity

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12 December 2020

Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors

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12 December 2020

Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo

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12 December 2020

Neuroprotective role of dopamine against hippocampal cell death

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12 December 2020

Distinct functions of the two isoforms of dopamine D2 receptors

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12 December 2020

Mitochondria and Ca(2+)in cell physiology and pathophysiology

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12 December 2020

The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice.

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12 December 2020

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

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12 December 2020

Disruption of the GluR2-NSF interaction protects primary hippocampal neurons from ischemic stress

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12 December 2020

Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs

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12 December 2020

NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex

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12 December 2020

Differential roles for NSF and GRIP/ABP in AMPA receptor cycling

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12 December 2020

The phosphoinositide 3-kinase pathway

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12 December 2020

D(1) dopamine receptor stimulation increases GluR1 phosphorylation in postnatal nucleus accumbens cultures

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12 December 2020

Protective effect of dopamine D2 agonists in cortical neurons via the phosphatidylinositol 3 kinase cascade.

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12 December 2020

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

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12 December 2020

Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor

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12 December 2020

Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD.

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12 December 2020

Regulation of kainate receptors by protein kinase C and metabotropic glutamate receptors.

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12 December 2020

Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites

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12 December 2020

Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines

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12 December 2020

Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons

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12 December 2020

NMDA and beta1-adrenergic receptors differentially signal phosphorylation of glutamate receptor type 1 in area CA1 of hippocampus.

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12 December 2020

A region of the third intracellular loop of the short form of the D2 dopamine receptor dictates Gi coupling specificity

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12 December 2020

Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors.

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12 December 2020

D1 dopamine receptor stimulation increases the rate of AMPA receptor insertion onto the surface of cultured nucleus accumbens neurons through a pathway dependent on protein kinase A.

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12 December 2020

Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Metabotropic glutamate and dopamine receptors co-regulate AMPA receptor activity through PKA in cultured chick retinal neurones: effect on GluR4 phosphorylation and surface expression

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

A family of AMPA-selective glutamate receptors

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Molecular cloning and functional expression of glutamate receptor subunit genes

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Multiple D2 dopamine receptors produced by alternative RNA splicing

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

The dopamine D2 receptor: two molecular forms generated by alternative splicing

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Alternative splicing directs the expression of two D2 dopamine receptor isoforms.

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12 December 2020

The major dopamine D2 receptor: molecular analysis of the human D2A subtype

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Neuropeptides in neurological disease

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Neuronal alterations in hippocampus following severe hypoglycaemia: a light microscopic and ultrastructural study in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Effect of hypocapnia on extracellular glutamate and glycine concentrations during the periischemic period in rabbit hippocampus

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12 December 2020

Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Differential tyrosine phosphorylation of N-methyl-D-aspartate receptor subunits

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Characterization of a chimeric human dopamine D3/D2 receptor functionally coupled to adenylyl cyclase in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Bromocriptine protects against delayed neuronal death of hippocampal neurons following cerebral ischemia in the gerbil

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Mechanisms of intracellular protein transport

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

NMDA and non-NMDA receptor gene expression following global brain ischemia in rats: effect of NMDA and non-NMDA receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Two sites in the third inner loop of the dopamine D2 receptor are involved in functional G protein-mediated coupling to adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons.

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked.

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12 December 2020

Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Dopamine-glutamate interactions in the striatum: behaviourally relevant modification of excitotoxicity by dopamine receptor-mediated mechanisms

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Akt signaling: linking membrane events to life and death decisions

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

PI3K: downstream AKTion blocks apoptosis

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

1 reference

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12 December 2020

Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Determination of the time course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified multiwell plate fluorescence scanner

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https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Chimeric D2/D3 dopamine receptor coupling to adenylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Sublethal oxygen-glucose deprivation alters hippocampal neuronal AMPA receptor expression and vulnerability to kainate-induced death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Dopamine and N-methyl-D-aspartate receptor interactions in the neostriatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Calcium, free radicals and excitotoxins in neuronal apoptosis.

1 reference

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12 December 2020

A revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.

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12 December 2020

NSF binding to GluR2 regulates synaptic transmission

1 reference

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12 December 2020

The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Dopamine D2 receptor agonists protect against ischaemia-induced hippocampal neurodegeneration in global cerebral ischaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Mitochondria and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors.

1 reference

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12 December 2020

Rapid Ca2+ entry through Ca2+-permeable AMPA/Kainate channels triggers marked intracellular Ca2+ rises and consequent oxygen radical production.

1 reference

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12 December 2020

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

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12 December 2020

Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death

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12 December 2020

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15858065

12 December 2020

10.1523/JNEUROSCI.5099-04.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725121&resulttype=core&format=json

12 May 2020

1 reference

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12 May 2020

PubMed publication ID

15858065

1 reference