Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death. (Q45249955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Mark Wogulis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sarah Wright

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Damian Cunningham

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Tamie Chilcote

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Kyle Powell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Russell E Rydel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

1 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

1071-1080

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction

8 January 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Reversible inactivation of superoxide-sensitive aconitase in Abeta1-42-treated neuronal cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Astrocytes contribute to neuronal impairment in beta A toxicity increasing apoptosis in rat hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Effect of beta-amyloid on endothelial cells: lack of direct toxicity, enhancement of MTT-induced cell death and intracellular accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

beta-Amyloid peptide in vitro toxicity: lot-to-lot variability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Self-assembly of Abeta(1-42) into globular neurotoxins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Folding proteins in fatal ways

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Astrocyte modulation of in vitro beta-amyloid neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Beta-amyloid-induced cell toxicity: enhancement of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide-dependent cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

beta-Amyloid-mediated inhibition of redox activity (MTT reduction) is not an indicator of astroglial degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

All-D-enantiomers of beta-amyloid exhibit similar biological properties to all-L-beta-amyloids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Stopped-flow kinetics reveal multiple phases of thioflavin T binding to Alzheimer beta (1-40) amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

The Toxicity of the Alzheimer's β-Amyloid Peptide Correlates with a Distinct Fiber Morphology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15689542

12 December 2020

10.1523/JNEUROSCI.2381-04.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689542%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

15689542

1 reference