Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial. (Q45050218)

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scientific article published on 14 November 2014

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English	Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.	scientific article published on 14 November 2014

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24 February 2020

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial (English)

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24 February 2020

phase I clinical trial

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phase II clinical trial

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24 February 2020

Geoffrey R Hill

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Kelli P MacDonald

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Glen A Kennedy

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Antiopi Varelias

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Slavica Vuckovic

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Laetitia Le Texier

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Ping Zhang

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Lisa Anderson

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Justine Leach

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Elise Sturgeon

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Judy Avery

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Stuart D Olver

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Mary Lor

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24 February 2020

Ashish K Misra

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Cheryl Hutchins

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A James Morton

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Elango Subramoniapillai

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Jason P Butler

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Cameron I Curley

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Simon Ts Durrant

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publication date

14 November 2014

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24 February 2020

Lancet Oncology Commission

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1451-1459

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24 February 2020

The biology of graft-versus-host disease: experimental systems instructing clinical practice

1 reference

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based on heuristic

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Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation

1 reference

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based on heuristic

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Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network

1 reference

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Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.

1 reference

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Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation

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The pro- and anti-inflammatory properties of the cytokine interleukin-6.

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The IL-17 differentiation pathway and its role in transplant outcome

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Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors

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Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: Regression modeling

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lumi: a pipeline for processing Illumina microarray

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Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS.

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Model-based variance-stabilizing transformation for Illumina microarray data.

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A new non-linear normalization method for reducing variability in DNA microarray experiments

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Granulocyte-colony-stimulating factor (G-CSF)-primed allogeneic bone marrow: significantly less graft-versus-host disease and comparable engraftment to G-CSF-mobilized peripheral blood stem cells.

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Allogeneic peripheral blood stem-cell compared with bone marrow transplantation in the management of hematologic malignancies: an individual patient data meta-analysis of nine randomized trials

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SOCS3 regulates graft-versus-host disease

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Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia

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10.1016/S1470-2045(14)71017-4

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PubMed publication ID

1 reference

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