PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption (Q44270131)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

author name string

Parvi T Lakkakorpi

1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Andrew J Bett

2

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Lorraine Lipfert

3

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Gideon A Rodan

4

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Le T Duong

5

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

language of work or name

0 references

publication date

3 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

11502-11512

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Regulation of osteoclast function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Cell biology of the osteoclast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Integrins and signaling in osteoclast function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Echistatin is a potent inhibitor of bone resorption in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Vitronectin receptor has a role in bone resorption but does not mediate tight sealing zone attachment of osteoclasts to the bone surface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

RAFTK/Pyk2-mediated cellular signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Convergence of alpha(v)beta(3) integrin- and macrophage colony stimulating factor-mediated signals on phospholipase Cgamma in prefusion osteoclasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Pyk2/CAKbeta tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Modulation of osteoclast function by adenovirus vector-induced epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

In vitro and in vivo suppression of osteoclast function by adenovirus vector-induced csk gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206579200

21 January 2018

Identifiers

10.1074/JBC.M206579200

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44270131&oldid=2109029972"