Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. (Q43122600)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jonathan H Rayment

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Shoukat Dedhar

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

9

G B Mills

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

6

B Hennessy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

L Huck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

D E White

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

V Sanguin-Gendreau

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

D Zuo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

R St-Arnaud

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

C J Marshall

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

W J Muller

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

22 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

3374-3385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

21 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

The integrin-linked kinase (ILK) suppresses anoikis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Breast cancer progression: controversies and consensus in the molecular mechanisms of metastasis and EMT

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Pharmacodynamic markers of perifosine efficacy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integrin-linked kinase--essential roles in physiology and cancer biology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Collagen reorganization at the tumor-stromal interface facilitates local invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Generalized lacZ expression with the ROSA26 Cre reporter strain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.86

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.86

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20305688%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 January 2020

1008550604

0 references

1 reference