DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation (Q42816808)

7 November 2017

title

DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation (English)

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7 November 2017

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C Blattner

1

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7 November 2017

E Tobiasch

2

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7 November 2017

M Litfen

3

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7 November 2017

H J Rahmsdorf

4

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7 November 2017

P Herrlich

5

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7 November 2017

language of work or name

English

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publication date

1 March 1999

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7 November 2017

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7 November 2017

volume

18

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7 November 2017

issue

9

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7 November 2017

page(s)

1723-1732

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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

7 November 2017

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7 January 2021

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein

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7 January 2021

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

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7 January 2021

UV-induced signal transduction

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7 January 2021

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

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7 January 2021

DNA damaging agents and growth factors induce changes in the program of expressed gene products through common routes

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

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7 January 2021

p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation

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7 January 2021

High-efficiency transformation of mammalian cells by plasmid DNA

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7 January 2021

Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

Inhibition of DNA replication factor RPA by p53.

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7 January 2021

p53 is covalently linked to 5.8S rRNA.

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7 January 2021

A DNA binding domain is contained in the C-terminus of wild type p53 protein

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7 January 2021

The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

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7 January 2021

p53 in growth control and neoplasia

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7 January 2021

p53 induction, cell cycle checkpoints, and apoptosis in DNAPK-deficient scid mice.

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

TFIIH: a key component in multiple DNA transactions

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Regulation of the specific DNA binding function of p53

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7 January 2021

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

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7 January 2021

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

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7 January 2021

p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells

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7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

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7 January 2021

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

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7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

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7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

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7 January 2021

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

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7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

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7 January 2021

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.

1 reference

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7 January 2021

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

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7 January 2021

Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.

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7 January 2021

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

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7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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7 January 2021

Negative feedback regulation of wild-type p53 biosynthesis.

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7 January 2021

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

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7 January 2021

Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53

1 reference

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Posttranscriptional regulation of c-fos mRNA expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

The multiple roles of transcription/repair factor TFIIH

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Fine mapping and regulation of the association of p53 with p34cdc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

p53 modulation of TFIIH–associated nucleotide excision repair activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Wild-type alternatively spliced p53: binding to DNA and interaction with the major p53 protein in vitro and in cells.

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7 January 2021

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Regulation of the p53 protein by protein kinase C alpha and protein kinase C zeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202480

7 January 2021

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells

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7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202480

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Dimensions Publication ID

7 November 2017

1036191397

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1 reference