Rescue of an abasic hairpin ribozyme by cationic nucleobases: evidence for a novel mechanism of RNA catalysis (Q42675353)

4 November 2017

title

Rescue of an abasic hairpin ribozyme by cationic nucleobases: evidence for a novel mechanism of RNA catalysis (English)

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4 November 2017

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Lori L Lebruska

1

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4 November 2017

Iaroslav I Kuzmine

series ordinal

2

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4 November 2017

Martha J Fedor

series ordinal

3

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4 November 2017

publication date

1 April 2002

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4 November 2017

published in

Chemistry and Biology

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4 November 2017

volume

9

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4 November 2017

issue

4

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4 November 2017

page(s)

465-473

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The structural basis of ribosome activity in peptide bond synthesis

4 November 2017

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Effects of cobalt hexammine on folding and self-cleavage of the Neurospora VS ribozyme

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General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme

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An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis

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Metal ions play a passive role in the hairpin ribozyme catalysed reaction

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A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage

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Folding of the hairpin ribozyme in its natural conformation achieves close physical proximity of the loops

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RNA catalytic properties of the minimum (-)sTRSV sequence

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Tertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transfer

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Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme

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7 January 2021

A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking

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7 January 2021

The folding of the hairpin ribozyme: dependence on the loops and the junction

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Stability of hairpin ribozyme tertiary structure is governed by the interdomain junction

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Tertiary structure stabilization promotes hairpin ribozyme ligation

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7 January 2021

Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

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Direct Brønsted analysis of the restoration of activity to a mutant enzyme by exogenous amines

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Brønsted analysis of aspartate aminotransferase via exogenous catalysis of reactions of an inactive mutant

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7 January 2021

Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme

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7 January 2021

Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage

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7 January 2021

Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases

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7 January 2021

Structure-function relationships in the hammerhead ribozyme probed by base rescue

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7 January 2021

A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic mutations.

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Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligation

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7 January 2021

Inter-domain cross-linking and molecular modelling of the hairpin ribozyme

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7 January 2021

Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides

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Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes

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7 January 2021

Functional involvement of G8 in the hairpin ribozyme cleavage mechanism

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7 January 2021

Value of general Acid-base catalysis to ribonuclease a.

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7 January 2021

Kinetics and Mechanisms for the Cleavage and Isomerization of the Phosphodiester Bonds of RNA by Brønsted Acids and Bases

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7 January 2021

The internal equilibrium of the hairpin ribozyme: temperature, ion and pH effects

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Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions

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Crystal structure of a hepatitis delta virus ribozyme

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7 January 2021

A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center

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7 January 2021

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

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7 January 2021

A second catalytic metal ion in group I ribozyme

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7 January 2021

Metal ion catalysis in the Tetrahymena ribozyme reaction

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7 January 2021

Ribonuclease a: revealing structure-function relationships with semisynthesis

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7 January 2021

Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

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7 January 2021

pH dependencies of the Tetrahymena ribozyme reveal an unconventional origin of an apparent pKa.

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7 January 2021

Reaction conditions and kinetics of self-cleavage of a ribozyme derived from Neurospora VS RNA

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7 January 2021

A pH-sensitive RNA tertiary interaction affects self-cleavage activity of the HDV ribozymes in the absence of added divalent metal ion

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7 January 2021

In vitro selection of self-cleaving RNAs with a low pH optimum

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7 January 2021

10.1016/S1074-5521(02)00130-8

Identifiers

DOI

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4 November 2017

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