BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects (Q42475620)

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scientific article published on July 2005

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English	BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects	scientific article published on July 2005

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scholarly article

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Europe PubMed Central

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1 November 2017

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects (English)

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1 November 2017

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Robert H. Lipsky

10

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1 November 2017

author name string

Xueying Jiang

1

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1 November 2017

Ke Xu

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Joelle Hoberman

3

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1 November 2017

Feng Tian

4

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1 November 2017

Aimee J Marko

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1 November 2017

Juwaria F Waheed

6

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1 November 2017

Claudia R Harris

7

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1 November 2017

Ann M Marini

8

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1 November 2017

Mary-Anne Enoch

9

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1 November 2017

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1 July 2005

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Neuropsychopharmacology

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1 November 2017

30

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1 November 2017

7

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1 November 2017

1353-1361

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1 November 2017

Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons.

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Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior

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A systematic method for clinical description and classification of personality variants. A proposal

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

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A comparison of linkage disequilibrium measures for fine-scale mapping

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Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

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A diagnostic interview: the schedule for affective disorders and schizophrenia

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Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder

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Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior

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Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation

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Nuclear factor kappaB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection

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Long-Term Potentiation and Memory

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Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

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Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate

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Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose

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Serotonin transporter: gene, genetic disorders, and pharmacogenetics

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Attenuation of the seizure-induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin-dependent protein kinases

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Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder

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The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.

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Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type.

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Determination of melting temperature for variant detection using dHPLC: a comparison between an empirical approach and DNA melting prediction software

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Up-regulation of the neuronal serotoninergic phenotype in vitro: BDNF and cAMP share Trk B-dependent mechanisms

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Inconsistent designs of association studies: a missed opportunity

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A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression

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Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

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Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I.

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Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

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A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF

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Association study of a brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and personality trait and intelligence in healthy young females

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An overview of the genetics of psychotic mood disorders

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Linkage Disequilibrium of the Brain-Derived Neurotrophic FactorVal66MetPolymorphism in Children With a Prepubertal and Early Adolescent Bipolar Disorder Phenotype

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Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression

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Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.

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Differential activation of brain-derived neurotrophic factor gene promoters I and III by Ca2+ signals evoked via L-type voltage-dependent and N-methyl-D-aspartate receptor Ca2+ channels

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The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB.

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10.1038/SJ.NPP.1300703

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Europe PubMed Central

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1 November 2017

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Europe PubMed Central

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1 November 2017

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