Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS. (Q42198095)

18 October 2017

Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS. (English)

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18 October 2017

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18 October 2017

6

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18 October 2017

Donatella Amatore

1

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Dolores Limongi

Dolores Limongi

5

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Sara Baldelli

Sara Baldelli

4

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Lucia Nencioni

Lucia Nencioni

7

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Katia Aquilano

Katia Aquilano

3

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Anna Teresa Palamara

Anna Teresa Palamara

10

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author name string

Enrico Garaci

8

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PMC publication ID

4311438

18 October 2017

Maria Rosa Ciriolo

9

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18 October 2017

7 October 2014

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18 October 2017

Cellular Microbiology

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18 October 2017

17

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18 October 2017

1

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18 October 2017

131-145

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Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection

18 October 2017

1 reference

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Human viral diseases: what is next for antiviral drug discovery?

26 October 2017

1 reference

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The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

26 October 2017

1 reference

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NLRP3 inflammasome: key mediator of neuroinflammation in murine Japanese encephalitis

26 October 2017

1 reference

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Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme

26 October 2017

1 reference

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Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

26 October 2017

1 reference

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Intracellular redox signaling as therapeutic target for novel antiviral strategy

26 October 2017

1 reference

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Redox regulation of the influenza hemagglutinin maturation process: a new cell-mediated strategy for anti-influenza therapy

26 October 2017

1 reference

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Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation

26 October 2017

1 reference

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The HA and NS Genes of Human H5N1 Influenza A Virus Contribute to High Virulence in Ferrets

26 October 2017

1 reference

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Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

26 October 2017

1 reference

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Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism

26 October 2017

1 reference

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Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression

26 October 2017

1 reference

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Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation

26 October 2017

1 reference

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Oxidative damage to neurons caused by the induction of microglial NADPH oxidase in encephalomyocarditis virus infection

26 October 2017

1 reference

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Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress

26 October 2017

1 reference

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Bcl-2 expression and p38MAPK activity in cells infected with influenza A virus: impact on virally induced apoptosis and viral replication

26 October 2017

1 reference

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Molecular mechanisms and clinical implications of reversible protein S-glutathionylation

26 October 2017

1 reference

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Glutathione and copper, zinc superoxide dismutase are modulated by overexpression of neuronal nitric oxide synthase

26 October 2017

1 reference

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Thiol chemistry in peroxidase catalysis and redox signaling

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells.

26 October 2017

1 reference

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The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

26 October 2017

1 reference

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Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

26 October 2017

1 reference

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Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

An absence of reactive oxygen species improves the resolution of lung influenza infection.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Inhibition of influenza A virus replication by resveratrol

26 October 2017

1 reference

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Protein measurement with the Folin phenol reagent

26 October 2017

1 reference

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Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide

26 October 2017

1 reference

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Redox signaling and the MAP kinase pathways

26 October 2017

1 reference

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Inhibition of influenza infection by glutathione

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells

26 October 2017

1 reference

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Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311438

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

26 October 2017

1 reference

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Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

26 October 2017

1 reference

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Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins

26 October 2017

1 reference

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Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

26 October 2017

1 reference

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Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection.

26 October 2017

1 reference

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Replication and plaque assay of influenza virus in an established line of canine kidney cells

26 October 2017

1 reference

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The role of phagocytes in HIV-related oxidative stress.

26 October 2017

1 reference

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29 May 2018

1 reference

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29 May 2018

1 reference

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Glutathione inhibits replication and expression of viral proteins in cultured cells infected with Sendai virus

29 May 2018

1 reference

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Interplay between redox status and inflammasome activation

29 May 2018

1 reference

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Crosstalk between platelet-derived growth factor-induced Nox4 activation and MUC8 gene overexpression in human airway epithelial cells.

17 August 2018

1 reference

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Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.

17 August 2018

1 reference

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17 August 2018

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17 August 2018

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17 August 2018

1 reference

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p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1.

17 August 2018

1 reference

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17 August 2018

1 reference

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Virus-induced formation of reactive oxygen intermediates in phagocytic cells

17 August 2018

1 reference

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Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue

17 August 2018

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VAS2870 is a pan-NADPH oxidase inhibitor

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Identifiers

DOI

10.1111/CMI.12343

1 reference

18 October 2017

1 reference

PMC publication ID

4311438

18 October 2017

PubMed publication ID

25154738

1 reference

PMC publication ID

4311438