cystic fibrosis transmembrane conductance regulator (Q420470)

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mammalian protein found in Homo sapiens
  • channel conductance-controlling ATPase
  • cAMP-dependent chloride channel
  • ATP-binding cassette sub-family C member 7
  • 3.6.3.49
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • CFTR
  • cystic fibrosis transmembrane conductance regulating
edit
Language Label Description Also known as
English
cystic fibrosis transmembrane conductance regulator
mammalian protein found in Homo sapiens
  • channel conductance-controlling ATPase
  • cAMP-dependent chloride channel
  • ATP-binding cassette sub-family C member 7
  • 3.6.3.49
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • CFTR
  • cystic fibrosis transmembrane conductance regulating

Statements

molecular function
protein binding
determination method or standard
IPI
20 references
retrieved
9 May 2019
stated in
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
SLC26A9 stimulates CFTR expression and function in human bronchial cell lines
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
CFTR and TMEM16A are separate but functionally related Cl- channels
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Investigating CFTR and KCa3.1 Protein/Protein Interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
retrieved
9 May 2019
stated in
Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IPI
chloride channel activity
determination method or standard
IDA
IEA
IMP
TAS
12 references
retrieved
9 May 2019
stated in
Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
TAS
retrieved
9 May 2019
stated in
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
9 May 2019
stated in
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
CFTR and TMEM16A are separate but functionally related Cl- channels
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
A monomer is the minimum functional unit required for channel and ATPase activity of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mechanism of direct bicarbonate transport by the CFTR anion channel
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Dynamic control of cystic fibrosis transmembrane conductance regulator Cl(-)/HCO3(-) selectivity by external Cl(-)
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
cell component
plasma membrane
determination method or standard
IDA
TAS
IEA
6 references
retrieved
26 September 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
TAS
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
26 September 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
26 September 2017
stated in
CFTR and TMEM16A are separate but functionally related Cl- channels
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
apical plasma membrane
determination method or standard
IDA
IEA
IMP
8 references
retrieved
26 September 2017
stated in
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
26 September 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
26 September 2017
stated in
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
SLC26A9 stimulates CFTR expression and function in human bronchial cell lines
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
plasma membrane
determination method or standard
IBA
IDA
IEA
TAS
9 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
TAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Sec16A is critical for both conventional and unconventional secretion of CFTR.
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
CFTR and TMEM16A are separate but functionally related Cl- channels
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IBA
apical plasma membrane
determination method or standard
IBA
IDA
IEA
IMP
9 references
retrieved
9 May 2019
stated in
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
SLC26A9 stimulates CFTR expression and function in human bronchial cell lines
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IBA
biological process
chloride transmembrane transport
determination method or standard
IDA
IEA
IMP
6 references
retrieved
26 September 2017
stated in
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
26 September 2017
stated in
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
26 September 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
26 September 2017
stated in
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
A monomer is the minimum functional unit required for channel and ATPase activity of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
26 September 2017
stated in
Mechanism of direct bicarbonate transport by the CFTR anion channel
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P13569&geneProductId=UniProtKB:P13569
determination method or standard
IDA
chloride transmembrane transport
determination method or standard
IBA
IDA
IEA
IMP
7 references
retrieved
9 May 2019
stated in
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
9 May 2019
stated in
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IEA
retrieved
9 May 2019
stated in
Mechanism of direct bicarbonate transport by the CFTR anion channel
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
A monomer is the minimum functional unit required for channel and ATPase activity of the cystic fibrosis transmembrane conductance regulator
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
GOA
curator
UniProt
UniProt protein ID
P13569
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13569
determination method or standard
IBA
EC enzyme number
5.6.1.6
1 reference
stated in
ENZYME
retrieved
9 September 2019
Commons category
Cystic fibrosis transmembrane conductance regulator
0 references

Identifiers

Microsoft Academic ID
2778428886
0 references
2777893369
0 references
PDB structure ID
 
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