Protein tyrosine kinases and cancer (Q41679383)

7 October 2017

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title

Protein tyrosine kinases and cancer (English)

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7 October 2017

2

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7 October 2017

K S Kolibaba

1

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7 October 2017

publication date

1 December 1997

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Biochimica et Biophysica Acta

7 October 2017

published in

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7 October 2017

volume

1333

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7 October 2017

issue

3

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7 October 2017

page(s)

F217-48

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A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS

7 October 2017

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Protein-tyrosine kinases

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7 January 2021

Viruses, genes, and cancer. I. The discovery of cellular oncogenes and their role in neoplasia

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7 January 2021

Signal transduction by receptors with tyrosine kinase activity

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7 January 2021

Growth factor signaling by receptor tyrosine kinases

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7 January 2021

Signalling by receptor tyrosine kinases

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7 January 2021

Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer

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7 January 2021

Membrane bound receptor tyrosine kinases and chemical carcinogenesis

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7 January 2021

Prolactin-mediated gene activation in mammary epithelial cells

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7 January 2021

Mechanism of signaling by growth hormone receptor

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7 January 2021

Molecular mechanism of growth hormone action

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7 January 2021

Signal transduction by T- and B-cell antigen receptors: converging structures and concepts

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7 January 2021

Multichain immune recognition receptors: similarities in structure and signaling pathways

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

Cytokine signal transduction

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7 January 2021

Cytokine receptors and signal transduction

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7 January 2021

Cytokine receptor signalling

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7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

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7 January 2021

Hematopoietic receptor complexes

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7 January 2021

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

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7 January 2021

From form to function: signaling by protein tyrosine phosphatases.

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7 January 2021

Roles of protein-tyrosine phosphatases in growth factor signalling

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7 January 2021

Dimerization of cell surface receptors in signal transduction

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7 January 2021

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

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7 January 2021

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

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7 January 2021

Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

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7 January 2021

Membrane-associated tyrosine kinases as molecular switches

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7 January 2021

Jaks and Stats in signaling by the cytokine receptor superfamily

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7 January 2021

Tyr527 is phosphorylated in pp60c-src: implications for regulation

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7 January 2021

The cell cycle and c-Src

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7 January 2021

The when and how of Src regulation

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7 January 2021

Oncogenic activation of tyrosine kinases

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7 January 2021

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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7 January 2021

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family

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7 January 2021

Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential

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7 January 2021

Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion

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7 January 2021

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

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7 January 2021

Chronic myelomonocytic leukemia: Tel-a-kinase what Ets all about

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7 January 2021

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

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7 January 2021

Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts

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7 January 2021

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor).

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7 January 2021

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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7 January 2021

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

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7 January 2021

Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors

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7 January 2021

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

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7 January 2021

Structural organization of the bcr gene and its role in the Ph' translocation

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7 January 2021

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

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7 January 2021

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

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7 January 2021

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

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7 January 2021

Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

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7 January 2021

Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties

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7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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7 January 2021

The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts

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7 January 2021

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome

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7 January 2021

Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures

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7 January 2021

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

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7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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7 January 2021

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

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7 January 2021

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice

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7 January 2021

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

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7 January 2021

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

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7 January 2021

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

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7 January 2021

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

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7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

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7 January 2021

Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis

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7 January 2021

Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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7 January 2021

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

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7 January 2021

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

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7 January 2021

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

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7 January 2021

The Ets family of transcription factors

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7 January 2021

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

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7 January 2021

Abnormalities of chromosome 12p13 and malignant proliferation of eosinophils: a nonrandom association.

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7 January 2021

KRAS2 oncogene overexpression in myelodysplastic syndrome with translocation 5;12

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7 January 2021

Atypical chronic myelomonocytic leukemia with eosinophilia and translocation (5;12). A new association

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7 January 2021

Myelodysplastic syndrome associated with increased bone marrow fibrosis and translocation (5;12)(q33;p12.3)

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7 January 2021

t(5;12)(q31;p12). A clinical entity with features of both myeloid leukemia and chronic myelomonocytic leukemia

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7 January 2021

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

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7 January 2021

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class

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7 January 2021

The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

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7 January 2021

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

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7 January 2021

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Major nucleolar proteins shuttle between nucleus and cytoplasm

1 reference

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7 January 2021

Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth

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https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Interaction of nucleolar phosphoprotein B23 with nucleic acids

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7 January 2021

In vivo and in vitro phosphorylation studies of numatrin, a cell cycle regulated nuclear protein, in insulin-stimulated NIH 3T3 HIR cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Identification and characterization of a hexameric form of nucleolar phosphoprotein B23

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Oncogenic activation of the ret protooncogene in thyroid cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

A cluster of CpG islands at D10S94, near the locus responsible for multiple endocrine neoplasia type 2A (MEN2A)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Localisation of the gene for multiple endocrine neoplasia type 2A to a 480 kb region in chromosome band 10q11.2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

1 reference

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7 January 2021

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest origin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900022-X

7 January 2021

RET gene and its implications for cancer

1 reference

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7 January 2021

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis

1 reference

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7 January 2021

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

1 reference

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7 January 2021

Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

1 reference

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7 January 2021

Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours

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7 January 2021

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

1 reference

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7 January 2021

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

1 reference

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7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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7 January 2021

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

1 reference

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7 January 2021

Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

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7 January 2021

A t(10;17) translocation creates the RET/PTC2 chimeric transforming sequence in papillary thyroid carcinoma

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7 January 2021

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7 January 2021

Cell transformation by the viral src oncogene

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7 January 2021

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

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7 January 2021

EGF receptor amplification and expression in human brain tumours

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7 January 2021

Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors

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7 January 2021

A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors

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7 January 2021

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

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7 January 2021

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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7 January 2021

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

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7 January 2021

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

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7 January 2021

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

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7 January 2021

Mechanism of activation of the human trk oncogene

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7 January 2021

Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex

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7 January 2021

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

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7 January 2021

Low frequency of rearrangements of the ret and trk proto-oncogenes in Japanese thyroid papillary carcinomas

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7 January 2021

Mechanism of met oncogene activation

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7 January 2021

The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions

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7 January 2021

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

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7 January 2021

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

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7 January 2021

Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface

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7 January 2021

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

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7 January 2021

c-erbB-2 amplification and overexpression in breast cancer: evaluation and comparison of Southern blot, slot blot, ELISA and immunohistochemistry

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7 January 2021

Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells

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7 January 2021

Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene

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7 January 2021

Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor

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7 January 2021

The epidermal growth factor receptor and the prognosis of bladder cancer.

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7 January 2021

Epidermal growth factor receptor (EGFr); results of a 6 year follow-up study in operable breast cancer with emphasis on the node negative subgroup

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7 January 2021

Epidermal growth factor receptor and prognosis in human breast cancer: a prospective study

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7 January 2021

Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs).

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7 January 2021

Epidermal growth factor receptors in lung tumours

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7 January 2021

Epidermal growth factor receptors in non-small cell lung cancer

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7 January 2021

Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival

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7 January 2021

The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long term survival

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7 January 2021

Prognostic significance of transforming growth factor-alpha in human esophageal carcinoma. Implication for the autocrine proliferation

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7 January 2021

Growth factor receptors and oncogene expression in prostate cells.

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7 January 2021

Epidermal Growth Factor Receptor mRNA Levels in Human Prostatic Tumors and Cell Lines

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7 January 2021

Investigation of the expression of epidermal growth factor receptor and blood group A antigen in 110 human gliomas

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7 January 2021

Expression of growth factor receptors in human brain tumours

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7 January 2021

Epidermal growth factor receptor in human brain tumors

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7 January 2021

Expression of the epidermal growth factor receptor in astrocytic tumours is specifically associated with glioblastoma multiforme

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7 January 2021

Epidermal growth factor receptor activity and clinical outcome in glioblastoma and meningioma

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7 January 2021

Amplification of Epidermal Growth Factor Receptor Gene in Gliomas: Histopathology and Prognosis

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7 January 2021

Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis.

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7 January 2021

Evaluation of epidermal growth factor receptors in bladder tumours

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7 January 2021

Epidermal growth factor receptor in human bladder cancer: a comparison of immunohistochemistry and ligand binding

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7 January 2021

Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder

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7 January 2021

Expression of epidermal growth factor receptor in invasive transitional cell carcinoma of the urinary bladder. A multivariate survival analysis

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7 January 2021

Alterations in phenotypic biochemical markers in bladder epithelium during tumorigenesis

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7 January 2021

Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance

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7 January 2021

Platelet-derived growth factor (PDGF) receptor activation in cell transformation and human malignancy

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7 January 2021

Genetic aberrations in human brain tumors

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7 January 2021

Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro

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7 January 2021

Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells

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7 January 2021

Growth factor and peptide receptors in small cell lung cancer

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7 January 2021

Selective growth in serum-free hormone-supplemented medium of tumor cells obtained by biopsy from patients with small cell carcinoma of the lung

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7 January 2021

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts

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7 January 2021

Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro

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7 January 2021

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

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7 January 2021

The role of the insulin-like growth factor system in human cancer

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7 January 2021

Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors

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7 January 2021

Insulin-like growth factors in human breast cancer

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7 January 2021

Type 1 IGF receptor in human breast diseases

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7 January 2021

Insulin-like growth factor-I (IGF-I) receptors in breast cancer.

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7 January 2021

Characterization of insulin-like growth factor II receptors in human small cell lung cancer cell lines

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7 January 2021

The IGF axis in the prostate

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7 January 2021

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

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7 January 2021

Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product

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7 January 2021

Physiological role of the insulin-like growth factor binding proteins

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7 January 2021

Insulin‐like growth factors

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7 January 2021

Role of Insulin‐like Growth Factor Binding Proteins in Modifying IGF Actionsa

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7 January 2021

Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy

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7 January 2021

Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells*

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7 January 2021

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

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7 January 2021

The neu oncogene encodes an epidermal growth factor receptor-related protein

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7 January 2021

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

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7 January 2021

HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma

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7 January 2021

What's new in breast cancer? Molecular perspectives of cancer development and the role of the oncogene c-erbB-2 in prognosis and disease

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7 January 2021

Overexpression of the c-erbB-2 oncoprotein: why does this occur more frequently in ductal carcinoma in situ than in invasive mammary carcinoma and is this of prognostic significance?

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7 January 2021

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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7 January 2021

c-erbB-2 oncoprotein expression in primary and advanced breast cancer

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7 January 2021

The long term prognostic significance of c-erbB-2 in primary breast cancer

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7 January 2021

Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer

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7 January 2021

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer

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7 January 2021

Prognostic significance of her-2/neu expression in breast cancer and its relationship to other prognostic factors

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7 January 2021

Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group.

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7 January 2021

Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance

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7 January 2021

The relationship between c-erbB-2 expression, S-phase fraction and prognosis in breast cancer

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7 January 2021

HER-2/neu oncogene protein and prognosis in breast cancer

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7 January 2021

Prognostic significance of HER-2 oncoprotein expression in breast cancer: a 30-year follow-up

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7 January 2021

c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodes

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7 January 2021

Overexpression of p53 and HER-2/neu proteins as prognostic markers in early stage breast cancer

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7 January 2021

Immunohistochemical detection of HER2/neu in patients with axillary lymph node negative breast carcinoma. A study of epidemiologic risk factors, histologic features, and prognosis.

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7 January 2021

Epidermal growth factor receptor (EGFr) as a marker for poor prognosis in node-negative breast cancer patients: Neu and tamoxifen failure

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7 January 2021

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

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7 January 2021

ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer

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7 January 2021

c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer

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7 January 2021

Protein kinases in human breast cancer

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7 January 2021

Predictive value of EGF receptor in breast cancer

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7 January 2021

Prognostic value of epidermal growth factor receptor in node-positive breast cancer

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7 January 2021

Expression of epidermal growth factor receptor in breast carcinoma

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7 January 2021

Human breast cancer: prognostic significance of the c-erbB-2 oncoprotein compared with epidermal growth factor receptor, DNA ploidy, and conventional pathologic features

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7 January 2021

Prospective study of the prognostic significance of epidermal growth factor receptor in primary breast cancer

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7 January 2021

Epidermal growth factor receptors and prognosis in primary breast cancer

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7 January 2021

Growth factor expression in Breast tissue

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7 January 2021

The prognostic significance of transforming growth factors in human breast cancer

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7 January 2021

Expression of epidermal growth factor receptors associated with lack of response to endocrine therapy in recurrent breast cancer

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7 January 2021

Relationship between epidermal growth factor receptor status and various prognostic factors in human breast cancer

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7 January 2021

Epidermal growth factor receptor in human breast cancer: correlation with cytosolic and nuclear ER receptors and with biological and histological tumor characteristics

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Epidermal growth factor receptor in human breast cancer: correlation with steroid hormone receptors and axillary lymph node involvement

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Epidermal growth factor receptor in human breast cancers: Correlation with estrogen and progesterone receptors

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Immunocytochemical and biochemical analysis of epidermal growth factor receptor expression in human breast cancer tissues: relationship to estrogen receptor and lymphatic invasion

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Epidermal growth factor receptor in human breast cancer comparison with steroid receptors and other prognostic factors

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Epidermal growth factor receptor (EGFr) status associated with failure of primary endocrine therapy in elderly postmenopausal patients with breast cancer

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Prognostic significance of co-expression of c-erbB-2 oncoprotein and epidermal growth factor receptor in breast cancer patients

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Epidermal growth factor receptors in human breast cancer: a plea for standardisation of assay methodology

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Standards for the assessment of estrogen receptors in human breast cancer. Report of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam

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Oestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms.

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Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

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Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

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Interaction of the neu/p185 and EGF receptor tyrosine kinases: implications for cellular transformation and tumor therapy

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Transcripts for transforming growth factors in human breast cancer: clinical correlates

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Immunohistochemical studies on oncogene products (EGF-R, c-erbB-2) and growth factors (EGF, TGF-alpha) in human breast cancer: their relationship to oestrogen receptor status, histological grade, mitotic index and nodal status

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Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance

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TGF alpha and TGF beta expression in mammary carcinoma

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Identification of heregulin, a specific activator of p185erbB2

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Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships

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Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

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Clonal analysis of human colorectal tumors

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A genetic model for colorectal tumorigenesis

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Genetics, molecular biology and colorectal cancer

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Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

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Growth factors and oncogenes in human gastrointestinal carcinomas

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pp60c-src activation in human colon carcinoma

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Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

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Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

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Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis

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Endothelial receptor tyrosine kinases involved in angiogenesis.

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Angiogenesis in cancer, vascular, rheumatoid and other disease

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High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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Detection and quantification of vascular endothelial growth factor/vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis?

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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Putative tyrosine kinases expressed in K-562 human leukemia cells

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Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

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Endothelial Tie growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis

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Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor

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Tyrosine protein kinase inhibition and cancer.

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Tyrosine kinase inhibition: an approach to drug development

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A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic

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Signal transduction by the neu/erbB-2 receptor: a potential target for anti-tumor therapy

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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

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A recombinant form of Pseudomonas exotoxin A containing transforming growth factor alpha near its carboxyl terminus for the treatment of bladder cancer

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Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

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Specific targeting of a mutant, activated egf receptor found in glioblastoma using a monoclonal antibody

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Monoclonal antibody against the fusion junction of a deletion-mutant epidermal growth factor receptor

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A phase I study of an anti-epidermal growth factor receptor monoclonal antibody for the treatment of malignant gliomas

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Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu

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p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

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erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Significance of Vascular Endothelial Growth Factor/Vascular Permeability Factor for Solid Tumor Growth, and Its Inhibition by the Antibody

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Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

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Platelet-derived growth factor in human glioma

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7 January 2021

10.1016/S0304-419X(97)00022-X

Identifiers

DOI

1 reference

7 October 2017

1 reference