Mutagenesis in the P53 gene (Q41592432)

4 October 2017

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title

Mutagenesis in the P53 gene (English)

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4 October 2017

G P Pfeifer

1

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4 October 2017

G P Holmquist

series ordinal

2

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4 October 2017

publication date

1 August 1997

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Biochimica et Biophysica Acta

4 October 2017

published in

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4 October 2017

volume

1333

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4 October 2017

issue

1

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4 October 2017

page(s)

M1-8

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p53: at the crossroads of molecular carcinogenesis and risk assessment

4 October 2017

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Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

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7 January 2021

Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?

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7 January 2021

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene

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7 January 2021

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

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TP53 tumor suppressor gene: a model for investigating human mutagenesis

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7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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7 January 2021

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

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Potential effects of altered solar ultraviolet radiation on human skin cancer

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7 January 2021

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

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7 January 2021

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7 January 2021

Mutagenic specificity of ultraviolet light

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The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene

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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

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Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

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7 January 2021

In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction

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7 January 2021

Binding of transcription factors creates hot spots for UV photoproducts in vivo

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7 January 2021

Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions

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7 January 2021

Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells

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The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrene Diol Epoxide Is Capable of Inducing G.fwdarw.A and G.fwdarw.C, in Addition to G.fwdarw.T, Mutations

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7 January 2021

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

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7 January 2021

Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts

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7 January 2021

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

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7 January 2021

Nucleotide excision repair

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7 January 2021

DNA repair rates mapped along the human PGK1 gene at nucleotide resolution

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7 January 2021

Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer

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7 January 2021

Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra

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7 January 2021

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7 January 2021

The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype

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7 January 2021

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

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7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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7 January 2021

Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations

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7 January 2021

10.1016/S0304-419X(97)00004-8

Identifiers

DOI

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4 October 2017

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