Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy (Q41357976)

29 September 2017

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title

Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy (English)

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29 September 2017

Obrenovitch TP

1

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29 September 2017

Urenjak J

series ordinal

2

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29 September 2017

language of work or name

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1 January 1997

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29 September 2017

published in

Progress in Neurobiology

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29 September 2017

volume

51

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29 September 2017

issue

1

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29 September 2017

page(s)

39-87

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Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons

29 September 2017

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Sparing of cholinergic neurons following quinolinic acid lesions of the rat striatum

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Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat.

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Photothrombotic infarction triggers multiple episodes of cortical spreading depression in distant brain regions

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Global cerebral ischemia in the rat: online monitoring of oxygen free radical production using chemiluminescence in vivo.

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A fluid percussion model of experimental brain injury in the rat

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Protein synthesis in the hippocampal slice: transient inhibition by glutamate and lasting inhibition by ischemia

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7 January 2021

Glutamate-induced ribosomal disaggregation and ultrastructural changes in rat cortical neuronal culture: protective effect of horse serum

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7 January 2021

Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation

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7 January 2021

Acute glutamate toxicity in cultured cerebellar granule cells: agonist potency, effects of pH, Zn2+ and the potentiation by serum albumin

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7 January 2021

Potentiation of 45Ca uptake and acute toxicity mediated by the N-methyl-D-aspartate receptor: the effect of metal binding agents and transition metal ions

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7 January 2021

Characterization of the glutamate transporter in retinal cones of the tiger salamander

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7 January 2021

Increased mortality in female rats after brain trauma is associated with lower free Mg2+.

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7 January 2021

ATP and brain function

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7 January 2021

The role of glial cells in regulation of neurotransmitter amino acids in the external environment. II. Mechanism of aspartate transport

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7 January 2021

Sodium-dependent glutamate uptake as an activator of oxidative metabolism in primary astrocyte cultures from newborn rat

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7 January 2021

Microdialysis of interstitial amino acids during spreading depression and anoxic depolarization in rat neocortex

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7 January 2021

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

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7 January 2021

Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration

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7 January 2021

Responses to cortical injury: I. Methodology and local effects of contusions in the rat

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7 January 2021

Concussive brain injury is associated with a prolonged accumulation of calcium: a 45Ca autoradiographic study.

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7 January 2021

μ-, δ-, κ-Opioid receptors and their subtypes. A critical review with emphasis on radioligand binding experiments

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7 January 2021

Direct evidence that excitotoxicity in cultured neurons is mediated via N-methyl-D-aspartate (NMDA) as well as non-NMDA receptors

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7 January 2021

Development of excitatory amino acid induced cytotoxicity in cultured neurons

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7 January 2021

Pharmacological modification of glutamate neurotoxicity in vivo

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7 January 2021

The blood-brain barrier disruption to circulating proteins in the early period after fluid percussion brain injury in rats

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7 January 2021

Denervation releases a neuronal survival factor in adult rat hippocampus

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7 January 2021

Cellular uptake disguises action of L-glutamate on N-methyl-D-aspartate receptors. With an appendix: diffusion of transported amino acids into brain slices

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7 January 2021

Glutamate Toxicity: An Experimental and Theoretical Analysis

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7 January 2021

Induction of FOS and JUN proteins after focal ischemia in the rat: differential effect of the N-methyl-D-aspartate receptor antagonist MK-801

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7 January 2021

Glutamate efflux via the reversal of the sodium-dependent glutamate transporter caused by glycolytic inhibition in rat cultured astrocytes

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7 January 2021

The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat.

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7 January 2021

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

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7 January 2021

Pyridine nucleotide redox state and blood flow of the cerebral cortex following middle cerebral artery occlusion in the cat

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7 January 2021

Neurochemical and morphological changes associated with human epilepsy

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7 January 2021

Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat.

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7 January 2021

Substantia nigra lesion protects against ischemic damage in the striatum

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7 January 2021

Development of Epileptic Seizures through Brain Stimulation at Low Intensity

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7 January 2021

Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury

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7 January 2021

Efficacy of competitive vs noncompetitive blockade of the NMDA channel following traumatic brain injury

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7 January 2021

A critical assessment of noise-induced errors in 31P MRS: application to the measurement of free intracellular magnesium in vivo

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7 January 2021

Hypothermia attenuates the normal increase in interleukin 1 beta RNA and nerve growth factor following traumatic brain injury in the rat

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7 January 2021

Anoxic LTP is mediated by the redox modulatory site of the NMDA receptor

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7 January 2021

In CA1 hippocampal neurons, the redox state of NMDA receptors determines LTP expressed by NMDA but not by AMPA receptors

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7 January 2021

Brain damage in fatal non-missile head injury without high intracranial pressure

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7 January 2021

Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate

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7 January 2021

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

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7 January 2021

Comparison of seizures and brain lesions produced by intracerebroventricular kainic acid and bicuculline methiodide

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7 January 2021

Quantification of excitatory amino acid uptake at intact glutamatergic synapses by immunocytochemistry of exogenous D-aspartate

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7 January 2021

Brain hydroxyl radical generation in acute experimental head injury

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7 January 2021

Amino acids in the neuronal microenvironment of focal human epileptic lesions

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7 January 2021

Anoxic LTP sheds light on the multiple facets of NMDA receptors

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7 January 2021

Effect of anoxia on ion distribution in the brain

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7 January 2021

Changes in Extracellular Calcium Activity in Cerebral Ischaemia

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7 January 2021

Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex

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7 January 2021

Neurotoxicity of albumin in vivo

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7 January 2021

Regional brain glutamate transport in rats at normal and raised concentrations of circulating glutamate

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7 January 2021

Pretreatment with phencyclidine, an N-methyl-D-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury

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7 January 2021

Impact acceleration-induced severe diffuse axonal injury in rats: characterization of phosphate metabolism and neurologic outcome

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7 January 2021

Extracellular free calcium and potassium during paroxsmal activity in the cerebral cortex of the cat.

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7 January 2021

Neurotoxicity at the N-methyl-D-aspartate receptor in energy-compromised neurons. An hypothesis for cell death in aging and disease.

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7 January 2021

Effects of a glutamate uptake inhibitor on glutamate release induced by veratridine and ischemia

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7 January 2021

Application of potassium chloride to the brain surface induces the c-fos proto-oncogene: reversal by MK-801.

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7 January 2021

Inhibition of glutamate release by arachidonic acid in rat cerebrocortical synaptosomes

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7 January 2021

Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation

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7 January 2021

A selective N-methyl-D-aspartate antagonist depresses epileptiform activity in rat hippocampal slices

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7 January 2021

Differences in striatal extracellular amino acid concentrations between Wistar and Fischer 344 rats after middle cerebral artery occlusion

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7 January 2021

Modulation of glutamate release by a kappa-opioid receptor agonist in rodent and primate striatum.

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7 January 2021

Increased extracellular levels of ascorbate in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis

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7 January 2021

Effects of quisqualic acid and glutamate on subsequent learning, emotionality, and seizure susceptibility in the immature and mature animal

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7 January 2021

Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury

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7 January 2021

The uptake inhibitor L-trans-PDC enhances responses to glutamate but fails to alter the kinetics of excitatory synaptic currents in the hippocampus

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7 January 2021

Increased NMDA responses and dendritic degeneration in human epileptic hippocampal neurons in slices.

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7 January 2021

Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats

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7 January 2021

Selective excitotoxic pathology in the rat hippocampus

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7 January 2021

Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat

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7 January 2021

Lasting neuron depression induced by high potassium and its prevention by low calcium and NMDA receptor blockade.

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7 January 2021

Role of calcium channels in spreading depression in rat hippocampal slices.

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7 January 2021

Selective dendrite damage in hippocampal CA1 stratum radiatum with unchanged axon ultrastructure and glutamate uptake after transient cerebral ischaemia in the rat

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7 January 2021

Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid

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7 January 2021

Action of the neurotoxin kainic acid on high affinity uptake of L-glutamic acid in rat brain slices

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7 January 2021

Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate

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7 January 2021

Editing status at the Q/R site of glutamate receptor-A, -B, -5 and -6 subunit mRNA in the hippocampal kindling model of epilepsy

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7 January 2021

The elusive transporters with a high affinity for glutamate

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7 January 2021

Binding order of substrates to the (sodium + potassium ion)-coupled L-glutamic acid transporter from rat brain

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7 January 2021

Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis

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7 January 2021

Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury

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7 January 2021

NMDA application potentiates synaptic transmission in the hippocampus

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7 January 2021

Effect of Amygdaloid Kindling on the Content and Release of Amino Acids from the Amygdaloid Complex: In Vivo and In Vitro Studies

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7 January 2021

Protective effect of spreading depression against neuronal damage following cardiac arrest cerebral ischaemia.

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7 January 2021

Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury

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7 January 2021

Lactate accumulation following concussive brain injury: the role of ionic fluxes induced by excitatory amino acids.

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7 January 2021

Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors

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7 January 2021

Control of glial cell volume in anoxia. In vitro studies on ischemic cell swelling.

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7 January 2021

Direct detection of ascorbyl radical in experimental brain injury: microdialysis and an electron spin resonance spectroscopic study

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7 January 2021

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

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7 January 2021

Astrocytic swelling due to hypotonic or high K+ medium causes inhibition of glutamate and aspartate uptake and increases their release

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7 January 2021

Delayed neuronal death in the gerbil hippocampus following ischemia

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7 January 2021

Monosodium glutamate: increased neurotoxicity after removal of neuronal re-uptake sites

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7 January 2021

Suppressed epileptogenesis in BDNF mutant mice

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7 January 2021

Rapid shrinkage of rat striatal extracellular space after local kainate application and ischemia as recorded by impedance

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7 January 2021

Amino acids in rat striatal dialysates: methodological aspects and changes after electroconvulsive shock

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7 January 2021

Threshold of synaptically elicited cortical spreading depression: drug-induced changes in rats

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7 January 2021

Hippocampal pathology in fatal non-missile human head injury

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7 January 2021

A morphological study on glutamate-induced swelling of cultured astrocytes: Involvement of calcium and chloride ion mechanisms

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7 January 2021

Chronic steroid-responsive encephalitis without autoantibodies to glutamate receptor GluR3

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7 January 2021

Changes of local cerebral glucose utilization, DC potential and extracellular potassium concentration in experimental head injury of varying severity

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7 January 2021

Transient glucose hypermetabolism after acute subdural hematoma in the rat

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7 January 2021

Characterization of D-Aspartic Acid Uptake by Rat Hippocampal Slices and Effect of Ischemic Conditions

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7 January 2021

Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus

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7 January 2021

Extracellular Antioxidants and Amino Acids in the Cortex of the Rat: Monitoring by Microdialysis of Early Ischemic Changes

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7 January 2021

Pathophysiology of the migraine aura. The spreading depression theory

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7 January 2021

The Effect of Glutamate Receptor Blockade on Anoxic Depolarization and Cortical Spreading Depression

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7 January 2021

Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum

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7 January 2021

Neurochemical and Behavioral Aspects of Lamotrigine

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Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action

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Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex

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Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neuroglial cultures from rat cortex

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Inhibition of sodium-potassium-ATPase: a potentially ubiquitous mechanism contributing to central nervous system neuropathology

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Contributory mechanisms in the causation of neurodegenerative disorders

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Interactions between excitotoxins and the Na+/K+-ATPase inhibitor ouabain in causing neuronal lesions in the rat hippocampus

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The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones

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7 January 2021

The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study

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Treatment with an AMPA Antagonist 12 Hours following Severe Normothermic Forebrain Ischemia Prevents CA1 Neuronal Injury

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7 January 2021

Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death

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7 January 2021

Excitatory amino acids as a final common pathway for neurologic disorders.

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7 January 2021

Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis

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7 January 2021

In vivo inactivation of quisqualate: studies in the cat spinal cord

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7 January 2021

Kainate neurotoxicity and glutamate inactivation

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7 January 2021

Altered brain sodium channel transcript levels in human epilepsy

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Extracellular free potassium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus

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7 January 2021

The toxic effect of sodium L-glutamate on the inner layers of the retina.

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7 January 2021

Pre-incubation of synaptosomes with arachidonic acid potentiates inhibition of [3H]D-aspartate transport

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7 January 2021

Cyclic GMP modulators and excitotoxic injury in cerebral cortical cultures

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7 January 2021

Behavioral protection by moderate hypothermia initiated after experimental traumatic brain injury

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7 January 2021

Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: pharmacological characterization

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7 January 2021

Effect of the kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat.

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7 January 2021

Distribution of effects of the kappa-opioid agonist CI-977 on cerebral glucose utilization in rat brain

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7 January 2021

The relationship between glutamate release and cerebral blood flow after focal cerebral ischaemia in the cat: effect of pretreatment with enadoline (a kappa receptor agonist).

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7 January 2021

Delayed therapy of experimental ischemia with competitive N-methyl-D-aspartate antagonists in rabbits

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7 January 2021

Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices.

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7 January 2021

The effect of 2-amino-3-phosphonopropionic acid (AP-3) in the gerbil model of cerebral ischaemia

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7 January 2021

The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons

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7 January 2021

Functional implications of kappa opioid receptor-mediated modulation of glutamate transmission in the output regions of the basal ganglia in rodent and primate models of Parkinson's disease.

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7 January 2021

Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus

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7 January 2021

N-Methyl-D-aspartate receptor subunits NR1 and NR2C are overexpressed in the inferior colliculus of audiogenic mice

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7 January 2021

The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report

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7 January 2021

Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study

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Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia

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7 January 2021

Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia

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7 January 2021

Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia

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7 January 2021

Cortical spreading depression protects against subsequent focal cerebral ischemia in rats

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7 January 2021

Amino acid neurotransmission: spotlight on synaptic vesicles

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7 January 2021

N-methyl-D-aspartic acid receptor structure and function

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7 January 2021

Chronic infusion ofl-glutamate causes neurotoxicity in rat striatum

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7 January 2021

Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum

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7 January 2021

Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist

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7 January 2021

Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in developing rat central nervous system

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7 January 2021

Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development

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7 January 2021

Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: a review

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7 January 2021

Magnesium deficiency exacerbates and pretreatment improves outcome following traumatic brain injury in rats: 31P magnetic resonance spectroscopy and behavioral studies

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7 January 2021

Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model

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7 January 2021

Effects of the N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury

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7 January 2021

Effect of noncompetitive blockade of N-methyl-D-aspartate receptors on the neurochemical sequelae of experimental brain injury

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7 January 2021

Magnesium protects against neurological deficit after brain injury

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7 January 2021

Spreading depression of Leão in rodent and human cortex

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7 January 2021

Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models

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Excitatory amino acids in epilepsy and potential novel therapies

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Excitatory amino acid neurotoxicity and neurodegenerative disease

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7 January 2021

Predictive value of serum ionized but not total magnesium levels in head injuries

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7 January 2021

Role of metabotropic glutamate receptor subtypes in the patterning of epileptiform activities in vitro

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7 January 2021

Prevention of periinfarct direct current shifts with glutamate antagonist NBQX following occlusion of the middle cerebral artery in the rat

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7 January 2021

Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures

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7 January 2021

Dual inhibitory action of enadoline (CI977) on release of amino acids in the rat hippocampus

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7 January 2021

Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection

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The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats

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7 January 2021

Ischemic brain damage in a model of acute subdural hematoma

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7 January 2021

Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes

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7 January 2021

In vivo microdialysis of amino acid neurotransmitters in the hippocampus in amygdaloid kindled rat

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7 January 2021

The effect of the NMDA receptor antagonist, MK-801, on the course and outcome of kindling

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7 January 2021

Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study

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7 January 2021

The quaking mouse: an epileptic mutant with alterations affecting the modulatory mechanisms of the NMDA receptor complex

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7 January 2021

Regional differences in the inhibition of L-glutamate and L-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes by L-trans-pyrrolidine-2,4-dicarboxylate, threo-3-hydroxy-D-aspartate and D-aspartate

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7 January 2021

2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties

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7 January 2021

Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices

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7 January 2021

NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release

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7 January 2021

Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies

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7 January 2021

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

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7 January 2021

Preferential stimulation of glutamate release by 4-aminopyridine in rat striatum in vivo.

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Structure and function of the NMDA receptor channel

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7 January 2021

Bidirectional transfer between kindling induced by excitatory amino acids and electrical stimulation

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7 January 2021

Clinical experience with excitatory amino acid antagonist drugs

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7 January 2021

Long-term potentiation, protein kinase C, and glutamate receptors

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7 January 2021

Homologues of a K(+) channel blocker ?-dendrotoxin: characterization of synaptosomal binding sites and their coupling to elevation of cytosolic free calcium concentration

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7 January 2021

Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation

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7 January 2021

Characterization of cortical depolarizations evoked in focal cerebral ischemia

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7 January 2021

NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain

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7 January 2021

Neurotransmission. A retrograde step forward

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7 January 2021

Ion channels and the regulation of neurotransmitter glutamate release

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7 January 2021

Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry

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7 January 2021

Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.

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Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats

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Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels

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7 January 2021

Epileptic seizure activity in the acute phase following cortical impact trauma in rat.

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7 January 2021

Magnesium gates glutamate-activated channels in mouse central neurones

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7 January 2021

Brain tissue concentrations of ATP, phosphocreatine, lactate, and tissue pH in relation to reduced cerebral blood flow following experimental acute middle cerebral artery occlusion

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Combined intracerebral microdialysis and electrophysiological recording: methodology and applications

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7 January 2021

A rapid redistribution of hydrogen ions is associated with depolarization and repolarization subsequent to cerebral ischemia reperfusion

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7 January 2021

Extracellular neuroactive amino acids in the rat striatum during ischaemia: comparison between penumbral conditions and ischaemia with sustained anoxic depolarisation

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7 January 2021

Intracerebral microdialysis combined with recording of extracellular field potential: a novel method for investigation of depolarizing drugs in vivo

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7 January 2021

Evidence disputing the link between seizure activity and high extracellular glutamate

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7 January 2021

High extracellular potassium, and not extracellular glutamate, is required for the propagation of spreading depression

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7 January 2021

Inhibition of cortical spreading depression by L-701,324, a novel antagonist at the glycine site of the N-methyl-D-aspartate receptor complex

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7 January 2021

Intracerebral microdialysis: electrophysiological evidence of a critical pitfall

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7 January 2021

Evidence against high extracellular glutamate promoting the elicitation of spreading depression by potassium

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7 January 2021

The effect of lamotrigine upon development of cortical kindled seizures in the rat

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7 January 2021

Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation

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7 January 2021

The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat

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7 January 2021

Effects of unilateral cortex lesions on gene expression of rat cortical cholecystokinin neurons

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7 January 2021

Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate

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7 January 2021

Excitotoxin-mediated neuron death in youth and old age.

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7 January 2021

Glutamate neurotoxicity and Huntington's chorea

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7 January 2021

L-cysteine, a bicarbonate-sensitive endogenous excitotoxin

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7 January 2021

Metabotropic glutamate receptor subtypes differentially influence neuronal recovery from in vitro hypoxia/hypoglycemia in rat hippocampal slices

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7 January 2021

Arachidonic acid and lysophosphatidylcholine modulate excitatory transmitter amino acid release from the rat cerebral cortex

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7 January 2021

A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex

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7 January 2021

The chemical nature of the main central excitatory transmitter: a critical appraisal based upon release studies and synaptic vesicle localization

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7 January 2021

Study of Regional Cerebral Blood Flow in Experimental Head Injury: Changes Following Cerebral Contusion and During Spreading Depression

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7 January 2021

Therapeutic hypothermia is cytoprotective without attenuating the traumatic brain injury-induced elevations in interstitial concentrations of aspartate and glutamate

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7 January 2021

Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model

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7 January 2021

Increased transmitter amino acid concentration in human ventricular CSF after brain trauma

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7 January 2021

Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury

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7 January 2021

Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia

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7 January 2021

Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

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7 January 2021

Potentiation of cyanide neurotoxicity by blockade of ATP-sensitive potassium channels

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7 January 2021

Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid.

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7 January 2021

Accumulation of glutamic acid in the arcuate nucleus of the hypothalamus of the infant mouse followng subcutaneous administration of monosodium glutamate

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7 January 2021

Physiology and pharmacology of epileptiform activity induced by 4-aminopyridine in rat hippocampal slices

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7 January 2021

Blood-brain barrier abnormalities in the acquired immunodeficiency syndrome: immunohistochemical localization of serum proteins in postmortem brain

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7 January 2021

Brain Adenosine and Transmitter Amino Acid Release from the Ischemic Rat Cerebral Cortex: Effects of the Adenosine Deaminase Inhibitor Deoxycoformycin

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7 January 2021

Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor

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7 January 2021

The metabotropic glutamate receptors: structure and functions

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7 January 2021

Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex

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7 January 2021

Correlation between reactive sprouting and microtubule protein expression in epileptic hippocampus

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7 January 2021

L-aspartate-beta-hydroxamate exhibits mixed agonist/antagonist activity at the glutamate metabotropic receptor in rat neonatal cerebrocortial slices

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7 January 2021

Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia

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7 January 2021

Uptake of Exogenous Glutamate and Aspartate by Circumventricular Organs but Not Other Regions of Brain

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7 January 2021

Temporal profile of neuronal damage in a model of transient forebrain ischemia

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7 January 2021

Activation of postsynaptic metabotropic glutamate receptors by trans-ACPD hyperpolarizes neurons of the basolateral amygdala.

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7 January 2021

Tolerance to ketamine-induced blockade of cortical spreading depression transfers to MK-801 but not to AP5 in rats.

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7 January 2021

Comparative analysis of sodium-dependent L-glutamate transport of synaptosomal and astroglial membrane vesicles from mouse cortex

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7 January 2021

Chloride transport blockers inhibit the chloride-dependent glutamate binding to rat brain membranes

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7 January 2021

Spreading depression and central nervous system pharmacology

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7 January 2021

Modulation of membrane transport by free fatty acids: inhibition of synaptosomal sodium-dependent amino acid uptake

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7 January 2021

Failure of neuronal ion exchange, not potentiated excitation, causes excitotoxicity after inhibition of oxidative phosphorylation

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7 January 2021

Neurotoxic action of methyltetrahydrofolate in rat cerebellum unrelated to direct activation of kainate receptors

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7 January 2021

SjvO2 monitoring in head-injured patients

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7 January 2021

Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures

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7 January 2021

Involvement of GABA and ACh in retinal spreading depression: effects of "low calcium-high magnesium" solutions

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7 January 2021

Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

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7 January 2021

Intracerebral microdialysis of extracellular amino acids in the human epileptic focus

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7 January 2021

Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine

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7 January 2021

Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex

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7 January 2021

Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture

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7 January 2021

MR detection of cortical spreading depression immediately after focal ischemia in the rat.

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7 January 2021

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

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7 January 2021

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

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7 January 2021

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

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7 January 2021

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

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7 January 2021

Decreased GABA release following tonic-clonic seizures is associated with an increase in extracellular glutamate in rat hippocampus in vivo

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7 January 2021

Neuroprotective role of adenosine in cerebral ischaemia

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7 January 2021

Epileptiform activity induced by changes in extracellular potassium in hippocampus

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7 January 2021

Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study

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7 January 2021

Occurrence of a large Ca2+-independent release of glutamate during anoxia in isolated nerve terminals (synaptosomes).

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7 January 2021

Glutamate uptake from the synaptic cleft does not shape the decay of the non-NMDA component of the synaptic current

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7 January 2021

Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds

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7 January 2021

Reversible and Irreversible Neuronal Injury Induced by Intrahippocampal Infusion of the mGluR Agonist 1S,3R-ACPD in the Rat

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7 January 2021

Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo

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7 January 2021

Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues

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7 January 2021

Oxypurinol inhibits free radical release from the cerebral cortex of closed head injured rats

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7 January 2021

Protective effect of MK801 in experimental brain injury

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7 January 2021

The triggering of spreading depression in the chicken retina: a pharmacological study

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7 January 2021

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia

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7 January 2021

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

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7 January 2021

Ischemic flow threshold for extracellular glutamate increase in cat cortex

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7 January 2021

Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury

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7 January 2021

Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis

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7 January 2021

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

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7 January 2021

Uptake and release of N-methyl-D-aspartate by rat brain slices

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7 January 2021

A transient hypertensive opening of the blood-brain barrier can lead to brain damage. Extravasation of serum proteins and cellular changes in rats subjected to aortic compression

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7 January 2021

The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy

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7 January 2021

Magnesium and ketamine attenuate cognitive dysfunction following experimental brain injury

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7 January 2021

Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury.

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7 January 2021

Neurotransmission: harnessing fusion machinery at the synapse

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7 January 2021

Extracellular Potassium in the Mammalian Central Nervous System

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7 January 2021

Ultrastructural immunocytochemical observations on the localization, metabolism and transport of glutamate in normal and ischemic brain tissue.

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7 January 2021

The cortical ischaemic penumbra associated with occlusion of the middle cerebral artery in the cat: 1. Topography of changes in blood flow, potassium ion activity, and EEG

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7 January 2021

The use of in vivo fluorescence image sequences to indicate the occurrence and propagation of transient focal depolarizations in cerebral ischemia

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7 January 2021

Neuroprotective effects of 619C89, a use-dependent sodium channel blocker, in rat traumatic brain injury

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7 January 2021

Spreading depression following experimental head injury in the rat.

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7 January 2021

Effect of local infusion of glutamate analogues into the nucleus accumbens of rats: an electrochemical and behavioural study

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7 January 2021

Protection by NMDA antagonists against selective cell loss following transient ischaemia

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7 January 2021

Acidosis causes failure of astrocyte glutamate uptake during hypoxia

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7 January 2021

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms

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7 January 2021

Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake

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7 January 2021

Prolonged transient ischemia results in impaired CBF recovery and secondary glutamate accumulation in cats

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7 January 2021

Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology

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7 January 2021

Changes in extracellular potassium concentration in cortex and brain stem during the acute phase of experimental closed head injury

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7 January 2021

Glutamate-induced calcium loads: effects on energy metabolism and neuronal viability

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7 January 2021

Extracellular N-acetylaspartate in the rat brain: in vivo determination of basal levels and changes evoked by high K+.

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7 January 2021

Aminopyridines and synaptic transmission

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7 January 2021

Dendrotoxin, 4-aminopyridine, and beta-bungarotoxin act at common loci but by two distinct mechanisms to induce Ca2+-dependent release of glutamate from guinea-pig cerebrocortical synaptosomes

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7 January 2021

Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists

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7 January 2021

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

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7 January 2021

Domoic Acid and Amnesic Shellfish Poisoning - A Review

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7 January 2021

Acute responses to experimental blunt head trauma. Topography of cerebral cortical edema

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7 January 2021

Motor effects of intracaudate injection of excitatory amino acids

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7 January 2021

Prevention by eliprodil (SL 82.0715) of traumatic brain damage in the rat. Existence of a large (18 h) therapeutic window

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7 January 2021

Enhanced NMDA conductance can account for epileptiform activity induced by low Mg2+ in the rat hippocampal slice

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7 January 2021

Synaptic and intrinsic conductances shape picrotoxin-induced synchronized after-discharges in the guinea-pig hippocampal slice

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7 January 2021

The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.

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7 January 2021

Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane

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7 January 2021

NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats

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7 January 2021

Towards an understanding of the role of glutamate in neurodegenerative disorders: energy metabolism and neuropathology

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7 January 2021

Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site

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7 January 2021

Depolarization and hypoxia-induced cell damage in serum-free cultures of the rat cortex, and related extracellular glutamate changes

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7 January 2021

Efflux of glutamate produced by short ischemia of varied severity in rat striatum

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7 January 2021

Changes in extracellular glutamate concentration produced in the rat striatum by repeated ischemia

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7 January 2021

Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex

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7 January 2021

Postischemic synaptic physiology in area CA1 of the gerbil hippocampus studied in vitro

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7 January 2021

Effect of serum on intracellular calcium homeostasis and survival of primary cortical and hippocampal CA1 neurons following brief glutamate treatment

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7 January 2021

Delayed neuronal death after brief histotoxic hypoxia in vitro

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7 January 2021

Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats

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7 January 2021

Glutamate release from the retina during spreading depression

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7 January 2021

Light- and electron-microscopic changes in central nervous tissue after electrophoretic injection of glutamate

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7 January 2021

Picrotoxin-induced tonic-clonic seizures and lethality are decreased by MK-801 in developing rats

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7 January 2021

In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures

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7 January 2021

High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes

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7 January 2021

Glutamate Neurotoxicity and the Inhibition of Protein Synthesis in the Hippocampal Slice

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7 January 2021

Enhancement of NMDA receptor-mediated neurotoxicity in the hippocampal slice by depolarization and ischemia

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7 January 2021

Changes in extracellular amino acids during soman- and kainic acid-induced seizures

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7 January 2021

Selective loss of [3H]kainic acid and [3H]AMPA binding in layer VI of frontal cortex in Huntington's disease

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7 January 2021

Extracellular glutamate during focal cerebral ischaemia in rats: time course and calcium dependency

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7 January 2021

Release of endogenous glutamate from rat cortical slices in presence of the glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylic acid

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7 January 2021

In vivo models of cerebral ischemia: effects of parenterally administered NMDA receptor glycine site antagonists

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7 January 2021

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

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7 January 2021

Glutamate enhances brain damage and albumin content in cerebrospinal fluid after intracarotid protamine infusion

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7 January 2021

Brain microdialysis and its application for the study of animal behaviour

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7 January 2021

Isolated NMDA receptor-mediated synaptic responses express both LTP and LTD

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7 January 2021

Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia.

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7 January 2021

Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain

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7 January 2021

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction

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7 January 2021

Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBQX in maximal electroshock and chemoconvulsant seizure models

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7 January 2021

In vivo evidence of hydroxyl radical formation induced by elevation of extracellular glutamate after cerebral ischemia in the cortex of anesthetized rats

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7 January 2021

Hippocampal CA3 lesion prevents postconcussive metabolic dysfunction in CA1

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7 January 2021

Arachidonic acid inhibits uptake of glutamate and glutamine but not of GABA in cultured cerebellar granule cells

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7 January 2021

Excitatory amino acid analogues: neurotoxicity and seizures

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7 January 2021

The role of excitatory amino acids in severe brain trauma: opportunities for therapy: a review

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7 January 2021

Differential modulation of human glutamate transporter subtypes by arachidonic acid

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7 January 2021

Free fatty acids, neutral glycerides, and phosphoglycerides in transient focal cerebral ischemia

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7 January 2021

Extracellular glutamate: on-line monitoring using microdialysis coupled to enzyme-amperometric analysis

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7 January 2021

Excitatory amino acid-evoked calcium influx and calcium-dependent neurotoxicity in rat cortical cultures

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7 January 2021

10.1016/S0301-0082(96)00049-4

Identifiers

DOI

1 reference

29 September 2017

1 reference