Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid (Q41337809)

29 September 2017

Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid (English)

1 reference

29 September 2017

Laws AL

1

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29 September 2017

Matthew AM

series ordinal

2

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29 September 2017

Double JA

series ordinal

3

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29 September 2017

Bibby MC

series ordinal

4

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29 September 2017

language of work or name

English

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publication date

1 June 1995

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29 September 2017

6

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British Journal of Cancer

inferred from page(s)

published in

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29 September 2017

71

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29 September 2017

6

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29 September 2017

1204-1209

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Flavone acetic acid--from laboratory to clinic and back

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid).

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Flavone acetic acid (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Phase II trials of flavone acetic acid in advanced malignant melanoma and colorectal carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Transplantation of adenocarcinomas of the colon in mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488).

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Cultural and Antigenic Properties of Newly Established Cell Strains Derived From Adenocarcinomas of the Human Colon and Rectum

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Antiproliferative properties of flavone acetic acid (NSC 347512) (LM 975), a new anticancer agent

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Induction of natural killer cell activity by the antitumour compound flavone acetic acid (NSC 347 512).

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Anti-tumour activity of flavone acetic acid (NSC 347512) in mice--influence of immune status

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Flavone acetic acid directly induces expression of cytokine genes in mouse splenic leukocytes but not in human peripheral blood leukocytes

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512).

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033820

A simple method for the quantitative extraction of dye extravasated into the skin

19 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Activity of flavone acetic acid (NSC-347512) against solid tumors of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

In vitro chemosensitivity testing of flavone acetic acid (LM975; NSC 347512) and its diethylaminoethyl ester derivative (LM985; NSC 293015)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Immunomodulation of Natural Killer Cell Activity by Flavone Acetic Acid: Occurrence Via Induction of Interferon /beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Synthesis and anti-tumour activity of topologically-related analogues of flavoneacetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Vascular collapse after flavone acetic acid: a possible mechanism of its anti-tumour action

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Role of T cells and tumour necrosis factor in antitumour activity and toxicity of flavone acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Potential antitumor agents. 62. Structure-activity relationships for tricyclic compounds related to the colon tumor active drug 9-oxo-9H-xanthene-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Modulation of superoxide production from murine macrophages by the antitumour agent flavone acetic acid and xanthenone acetic acid analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7779712

12 December 2020

Identifiers

DOI

10.1038/BJC.1995.234

1 reference

Dimensions Publication ID

29 September 2017

0 references

1 reference

29 September 2017

PubMed publication ID

7779712

1 reference