Integrins and cancer (Q41238988)

28 September 2017

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title

Integrins and cancer (English)

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28 September 2017

Varner JA

1

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28 September 2017

Cheresh DA

series ordinal

2

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28 September 2017

publication date

1 October 1996

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Current Opinion in Cell Biology

28 September 2017

published in

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28 September 2017

volume

8

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28 September 2017

issue

5

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28 September 2017

page(s)

724-730

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Integrins: versatility, modulation, and signaling in cell adhesion

28 September 2017

cites work

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7 January 2021

Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin

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Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts

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7 January 2021

Signal transduction from the extracellular matrix

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The extracellular matrix as a cell survival factor

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7 January 2021

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

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Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts

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Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape

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Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor

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Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium

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Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells

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7 January 2021

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

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Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown

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7 January 2021

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

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Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

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Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2

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7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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7 January 2021

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

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7 January 2021

Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase

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7 January 2021

Induction of carcinoma cell migration on vitronectin by NF-kappa B-dependent gene expression.

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Fibroblast surface antigen produced but not retained by virus-transformed human cells

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Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells

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Changes in integrin receptors on oncogenically transformed cells.

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7 January 2021

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases

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7 January 2021

Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp-containing peptide overproduce the fibronectin receptor

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7 January 2021

The osteoblast-like differentiated phenotype of a variant of MG-63 osteosarcoma cell line correlated with altered adhesive properties

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7 January 2021

Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

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7 January 2021

The growth arrest-specific gene, gas1, is involved in growth suppression

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7 January 2021

Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene

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Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

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Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C

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7 January 2021

The novel structural motif Gln795-Gln802 in the integrin beta 1C cytoplasmic domain regulates cell proliferation

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7 January 2021

Alpha v-integrins in human melanoma: gain of alpha v beta 3 and loss of alpha v beta 5 are related to tumor progression in situ but not to metastatic capacity of cell lines in nude mice

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7 January 2021

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

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7 January 2021

Role of V Integrins and Vitronectin in Human Melanoma Cell Growth

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7 January 2021

Transformation and tumor progression are frequently associated with expression of the alpha 3/beta 1 heterodimer in solid tumors

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7 January 2021

The monoclonal antibody BQ16 identifies the alpha 6 beta 4 integrin on bladder cancer

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7 January 2021

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

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7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

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7 January 2021

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

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7 January 2021

Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain

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7 January 2021

In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells

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7 January 2021

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor

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7 January 2021

Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

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7 January 2021

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

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7 January 2021

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.

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7 January 2021

Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin

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7 January 2021

Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin

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7 January 2021

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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7 January 2021

Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression

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7 January 2021

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin

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7 January 2021

Requirement of vascular integrin alpha v beta 3 for angiogenesis

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7 January 2021

Basic fibroblast growth factor increases expression of the alpha v beta 3 integrin complex on human microvascular endothelial cells

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7 January 2021

Basic FGF and TGF-beta differentially modulate integrin expression of human microvascular endothelial cells

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7 January 2021

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

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7 January 2021

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

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7 January 2021

10.1016/S0955-0674(96)80115-3

Identifiers

DOI

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28 September 2017

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